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Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. 再加上，我们可以发GSTT1 抗体 (109) 和 GSTT1 试剂盒 (31)和数多这个蛋白质的别的产品。
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The meta-analysis showed that glutathione S-transferases GSTT1 and GSTM1 (显示 GSTM1 蛋白) null polymorphisms are risk factors for breast cancer [Meta-analysis].
individuals who have GSTT1 null variant are at higher risk for developing seizure than those of GSTT1 wild genotype.
The interaction of the MTHFR (显示 MTHFR 蛋白), GSTT1 and hypertension may constitute a predictive model of risk for early onset ischemic heart disease in the population of Yucatan, Mexico
The effects of GSTM1 (显示 GSTM1 蛋白)/GSTT1 genes on diabetes mellitus type 2 risk are gender dependent and may be triggered by tobacco smoking.
GSTT1 gene polymorphism is associated with liver diseases.
Authors conclude that maternal GSTM1 (显示 GSTM1 蛋白)/GSTT1 gene polymorphisms present an impact on birth weight, being involved in the neonatal nutritional status.
Indel variants of GSTT1 were typed in breast cancer patients and normal controls. No significant association was found.
The current analyses suggests significant association was found between GSTM1 (显示 GSTM1 蛋白) variants and the risk of childhood acute lymphoblastic leukemia (ALL), while no association were found between GSTT1 and GSTP1 (显示 GSTP1 蛋白) Ile105Val polymorphism and childhood ALL risk
In conclusion, the present study indicated that GSTT1 deletion was associated with increased recurrence risk of breast cancer, while GSTM1 (显示 GSTM1 蛋白) correlated with worst prognosis parameters at diagnosis, but was negatively associated with recurrence risk in luminal subtype samples.
Homozygous deletion of GSTT1 is associated with slower HIV disease progression.
minor structural changes in the C-terminal helix of mouse GST T1-1 induce major changes in the substrate-activity profile of the enzyme to favor novel chemical reactions and to suppress other reactions catalyzed by the parental enzyme
The carcinogenic effects of DCM in the mouse are caused by the interaction with DNA of a glutathione (GSH) conjugate that is produced by the class theta glutathione S-transferase T1-1 (GST T1-1).
Gstt1-null mice would be useful as an animal model of humans with the GSTT1-null genotype.
Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.
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