G-Elongation Factor, Mitochondrial 1 蛋白 (GFM1)

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. 再加上，我们可以发GFM1 抗体 (75) 和 GFM1 试剂盒 (11)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
GFM1 85476 Q96RP9
GFM1 28030 Q8K0D5
大鼠 GFM1 GFM1 114017 Q07803
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Showing 6 out of 9 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 人 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
详细
Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
详细
小麦胚 人 GST tag 2 μg Log in to see 11至12个工作日
$338.33
详细
HEK-293 Cells 人 Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$547.80
详细
大肠杆菌（E. Coli） 人 非结合性 SDS-PAGE analysis of Human GFM1 Protein. 100 μg Log in to see 11至18个工作日
$668.03
详细
大肠杆菌（E. Coli） 小鼠 非结合性 SDS-PAGE analysis of Mouse GFM1 Protein. 100 μg Log in to see 11至18个工作日
$710.67
详细

GFM1 蛋白 by Origin and Source

Origin 在表达 标记
Human , , ,
, , ,
Mouse (Murine) ,
,

更多G-Elongation Factor, Mitochondrial 1 (GFM1)互动伙伴

Human G-Elongation Factor, Mitochondrial 1 (GFM1) interaction partners

  1. Functional studies demonstrated decreased GFM1 protein levels, suggested disrupted assembly of mitochondrial complexes III and V and decreased activities of mitochondrial complexes I and IV, all indicating combined OXPHOS deficiency.

  2. In the present study, a nanoparticle modified with EGFP-EGF1 (ENP) was constructed as a multitargeting drug delivery system. The protein binding experiment showed EGFP-EGF1 could bind well to A549 tumor cells and other stromal cells including neo-vascular cells, tumor-associated fibroblasts, and tumor-associated macrophages

  3. The R671C mutation disrupts an inter-subunit interface and could locally destabilize the mutant protein. The second mutation (L398P) disrupted the H-bond network in a rich-beta-sheet domain, and may have a dramatic effect on local structure.

  4. analysis of molecular model for EF-G1 isoform

  5. Sequencing of EFG1 revealed a mutation affecting a conserved residue of the guanosine triphosphate (GTP)-binding domain. These results define a new class of gene defects underlying disorders of oxidative phosphorylation.

  6. mutations in the mitochondrial translation factor EFG1 may have a role in oxidative phosphorylation deficiencies [case report]

  7. Genetic investigation of patients with defective mitochondrial translation led to the discovery of novel mutations in the mitochondrial elongation factor G1 (EFG1) in one affected baby and in the mitochondrial elongation factor Tu (EFTu) in another one

蛋白简介GFM1

蛋白简介

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.

Gene names and symbols associated with GFM1

  • G elongation factor mitochondrial 1 (GFM1)
  • G elongation factor, mitochondrial 1 (Gfm1)
  • AW545374 蛋白
  • COXPD1 蛋白
  • D3Wsu133e 蛋白
  • EF-G 蛋白
  • Efg 蛋白
  • EFG1 蛋白
  • EFGM 蛋白
  • EGF1 蛋白
  • Gfm 蛋白
  • hEFG1 蛋白

Protein level used designations for GFM1

EF-Gmt , G translation elongation factor, mitochondrial , elongation factor G 1, mitochondrial , elongation factor G, mitochondrial , elongation factor G1 , mEF-G 1 , mitochondrial elongation factor G , mitochondrial elongation factor G1 , G elongation factor 1 , mitochondrial

GENE ID SPECIES
85476 Homo sapiens
28030 Mus musculus
114017 Rattus norvegicus
477128 Canis lupus familiaris
513309 Bos taurus
GFM1 蛋白 (GFM1) 精选生产商
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