anti-G Protein-Coupled Receptor 4 (GPR4) 抗体

Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.. 再加上,我们可以发GPR4 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GPR4 2828 P46093
GPR4 319197 Q8BUD0
GPR4 308408 Q4KLH9
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Showing 10 out of 43 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IHC, IHC (p) Anti-GPR4 antibody  ABIN1048817 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPR4 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11至14个工作日
$484.00
详细
非结合性 ICC, IHC, IHC (p) Anti-GPR4 antibody  ABIN1048818 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPR4 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11至14个工作日
$484.00
详细
Bat 非结合性 IHC, IHC (p) Anti-GPR4 antibody  ABIN1048816 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GPR4 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 11至14个工作日
$484.00
详细
非结合性 WB Western Blot: GPR4 Antibody [NBP1-33619] - Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 8至11个工作日
$514.63
详细
非结合性 WB GPR4 Antibody (Center) (ABIN1881386) western blot analysis in WiDr cell line and rat liver tissue lysates (35 µg/lane). This demonstrates the GPR4 antibody detected the GPR4 protein (arrow). 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 ICC, IHC (p) Immunohistochemistry-Paraffin: GPR4 Antibody [NLS145] - Analysis of anti-GPR4 antibody with human lung, adenocarcinoma. Immunocytochemistry/Immunofluorescence: GPR4 Antibody [NLS145] - Analysis of anti-GPR4 antibody with untransfected HEK293 human embryonic kidney cells. 0.05 mL Log in to see 10至13个工作日
$514.63
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 IHC (p) Immunohistochemistry-Paraffin: GPR4 Antibody [NLS144] - Analysis of anti-GPR4 antibody with human kidney, renal tubules at 15 ug/ml. Immunohistochemistry-Paraffin: GPR4 Antibody [NLS144] - Analysis of anti-GPR4 antibody with human kidney, renal tubules. 0.05 mL Log in to see 10至13个工作日
$514.63
详细
非结合性 WB   100 μL Log in to see 7至9个工作日
$507.83
详细

通过反应活性、应用领域、克隆类型和共轭标记 GPR4 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , ,


, ,
Mouse (Murine) ,


Rat (Rattus) ,


引用最多的anti-GPR4 抗体

  1. Human Polyclonal GPR4 Primary Antibody for WB - ABIN1881386 : Heiber, Docherty, Shah, Nguyen, Cheng, Heng, Marchese, Tsui, Shi, George: Isolation of three novel human genes encoding G protein-coupled receptors. in DNA and cell biology 1995 (PubMed)
    Show all 4 Pubmed References

更多抗GPR4的相互作用对抗体

Human G Protein-Coupled Receptor 4 (GPR4) interaction partners

  1. Proton-sensing GPR4 signaling mediated the proton-induced inhibitory effects on the osteogenesis of BMSCs. YAP (显示 YAP1 抗体) was the downstream effector of GPR4 signaling. Extracellular pH modulates the osteogenic responses of BMSCs by regulating the proton-sensing GPR4-YAP (显示 YAP1 抗体) pathway.

  2. These results suggest that zOGR1, but not GPR4, is also a metal-sensing G-protein-coupled receptor (显示 ADRA1A 抗体) in addition to a proton-sensing G-protein-coupled receptor (显示 ADRA1A 抗体), although not all metals that activate hOGR1 activated zOGR1.

  3. GPR4 blockade attenuated renal injury after IR and reduced the cell apoptosis through the suppression of CHOP (显示 DDIT3 抗体) expression.

  4. acidosis/GPR4-induced endoplasmic reticulum stress pathways in endothelial cells may regulate vascular growth and inflammatory response in the acidic microenvironment.

  5. it was demonstrated that GPR4 affects ECs by regulating Notch1 (显示 NOTCH1 抗体), a function that may be important for physiological and pathological angiogenesis.

  6. GPR4 induces angiogenesis via GPR4-induced p38 (显示 CRK 抗体)-mediated IL6 (显示 IL6 抗体), IL8 (显示 IL8 抗体) and VEGFA (显示 VEGFA 抗体) secretion at acidic extracellular pH in squamous cell carcinoma of the head and neck

  7. The results suggested that GPR4 may play an important role in the development of epithelial ovarian carcinoma (EOC), and its overexpression might be required for the angiogenesis, tumor growth, and metastasis of EOC

  8. acidosis/GPR4 signaling regulates endothelial cell adhesion mainly through the G(s)/cAMP/Epac (显示 RAPGEF3 抗体) pathway

  9. The mutation of histidine residue at 79, 165, or 269 from the N-terminal of GPR4 to phenylalanine shifted the half-maximal effective concentration (EC(50)) of proton-induced signaling activities to the right, including cAMP accumulation.

  10. Endogenous GPR4 in endothelial cells may be a potential G protein-coupled receptor (显示 ADRA1A 抗体) by which LPC (显示 PCSK7 抗体) signals proinflammatory activities.

Mouse (Murine) G Protein-Coupled Receptor 4 (GPR4) interaction partners

  1. GPR4 blockade attenuated renal injury after IR and reduced the cell apoptosis through the suppression of CHOP (显示 DDIT3 抗体) expression.

  2. Collectively, these results posit the acid sensor GPR4 as a novel component of central blood pressure control through interactions with the renin (显示 REN 抗体)-angiotensin system.

  3. knockdown of a proton-sensing G protein-coupled receptor (显示 GPR34 抗体) GPR4 markedly reduced CHOP (显示 DDIT3 抗体) expression and endothelial cell apoptosis after hypoxia exposure.

  4. The results indicate that through the G12 (显示 TCF3 抗体)/13/Rho signaling pathway GPR4 modulates focal adhesion dynamics and reduces cell spreading and membrane ruffling.

  5. The data identify GPR4 and TASK-2 (显示 KCNK5 抗体) as distinct, parallel, and essential central mediators of respiratory chemosensitivity.

  6. These results suggested that, at least in part, RANKL (显示 TNFSF11 抗体) expression by osteoblasts in an acidic environment was mediated by cAMP/PKA signaling resulting from GPR4 activation.

  7. GPR4 modulates glucose homeostasis by increasing insulin (显示 INS 抗体) sensitivity.

  8. Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor.

  9. findings suggest that GPR4 activation by an acidic pH inhibits tumor cell migration and invasion, and the Rho GTPase (显示 RACGAP1 抗体) is at least partly responsible for this phenotype

  10. These results suggest that GPR4 deficiency leads to partially penetrant vascular abnormalities during development and that this receptor functions in blood vessel pH sensing.

GPR4 抗原简介

蛋白简介

Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.

Gene names and symbols associated with GPR4

  • G protein-coupled receptor 4 (GPR4) 抗体
  • G protein-coupled receptor 4 (Gpr4) 抗体

Protein level used designations for GPR4

G-protein coupled receptor 19 , G-protein coupled receptor 4

GENE ID SPECIES
2828 Homo sapiens
319197 Mus musculus
308408 Rattus norvegicus
512876 Bos taurus
100144489 Sus scrofa
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