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The protein encoded by FOXK2 contains a fork head DNA binding domain. 再加上，我们可以发Forkhead Box K2 蛋白 (3)和数多这个蛋白质的别的产品。
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Human Polyclonal FOXK2 Primary Antibody for ELISA, WB - ABIN249974
Fujii, Nakamura: FOXK2 transcription factor is a novel G/T-mismatch DNA binding protein. in Journal of biochemistry 2010
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Cow (Bovine) Polyclonal FOXK2 Primary Antibody for IHC, WB - ABIN2776014
Liu, Chen, Li, Hsieh, Chen, Chen, Jeng, Chuang: Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a). in Proteins 2002
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FOXK2, regulted by miR (显示 MLXIP 抗体)-1271-5p, promotes cell growth and indicates unfavorable prognosis in hepatocellular carcinoma
SOX9 (显示 SOX9 抗体) transcriptionally activated FOXK2 was involved in the pathogenesis of colorectal cancer.FOXK2 is highly expressed in colorectal cancer tissues.
Results show that Foxk2 expression was downregulated in lung adenocarcinoma tissues and non-small cell lung cancer cell (NSCLC) lines. Its overexpression suppresses epithelial-mesenchymal transition in NSCLC cells and inhibits cell migration and invasion. Also, the expression of Foxk2 seems to be regulated by miR (显示 MLXIP 抗体)-1271.
FOXO3 (显示 FOXO3 抗体)-dependent gene regulation is generally mediated not through uniquely bound regions but through regions occupied by both FOXK2 and FOXO3 (显示 FOXO3 抗体) where both factors play a regulatory role.
FOXK2 might act as a negative regulator of ERalpha (显示 ESR1 抗体), and its association with both ERalpha (显示 ESR1 抗体) and BRCA1/BARD1 (显示 BARD1 抗体) could lead to the down-regulation of ERalpha (显示 ESR1 抗体) transcriptional activity, effectively regulating the function of ERalpha (显示 ESR1 抗体).
FOXK1 and FOXK2 positively regulate Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling by translocating dishevelled (显示 DVL2 抗体) proteins into the nucleus.
BAP1 (显示 RNF2 抗体) deficiency causes increased expression of FoxK2 target genes in a Ring1B (显示 RNF2 抗体)-Bmi1 (显示 BMI1 抗体)-dependent manner
FOXK2 can promote transcriptional activation and is required for the efficient recruitment of AP-1 (显示 FOSB 抗体) components to chromatin.
Data show that FOXK2 is subject to control by cell cycle-regulated hyperphosphorylation occurring in CDK (显示 CDK4 抗体)).cyclin (显示 PCNA 抗体)-dependent manner with CDK1 (显示 CDK1 抗体).cyclin B as the major kinase complex.
FOXK2 is a G/T-mismatch DNA-binding protein (显示 UBE2V1 抗体) and a deaminated DNA-binding protein (显示 UBE2V1 抗体)
FoxK2 is required for proliferation and survival.
Foxk1 (显示 Foxk1 抗体) and Foxk2 are identified as transcriptional repressors of autophagy in muscle cells and fibroblasts.
The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements.
, cellular transcription factor ILF-1
, forkhead box protein K2
, interleukin enhancer binding factor 1
, interleukin enhancer-binding factor 1
, forkhead box K2