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Possible transcriptional factor (By similarity)..
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Mouse (Murine) Polyclonal FOXI3 Primary Antibody for ELISA, WB - ABIN4312346
Drögemüller, Karlsson, Hytönen, Perloski, Dolf, Sainio, Lohi, Lindblad-Toh, Leeb: A mutation in hairless dogs implicates FOXI3 in ectodermal development. in Science (New York, N.Y.) 2008
Foxi3 regulates specification of hair follicle stem cell in embryogenesis, and is essential for hair follicle activation during hair regeneration.
Foxi3 is necessary to prime pre-placodal ectoderm for the correct interpretation of inductive signals for the otic and epibranchial placodes.
Foxi3 maintains dental epithelial cells in an undifferentiated state and thereby regulates multiple stages of tooth morphogenesis.
Data indicate that Foxi3 mutants succumb to apoptosis from embryonic day 9.75 onwards, and this cell death correlates with a delay in expression of Fgf8 in branchial arch ectoderm.
Eda (显示 EDA 抗体) and activin A (显示 INHBA 抗体) are upstream regulators of Foxi3 in skin appendage placodes
Foxi3 expressed in a broad region of the pan (显示 SUPT6H 抗体)-placodal ectoderm adjacent to the neural plate from E6.75 to first somite stage; expression restricted to ectoderm & endoderm of branchial pouches at E10.5
Possible transcriptional factor (By similarity).
forkhead box protein I3
, forkhead box I3