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The Fos gene family consists of 4 members FOSL1, and FOSL2. 再加上，我们可以发FBJ Murine Osteosarcoma Viral Oncogene Homolog B 蛋白 (7) 和 FBJ Murine Osteosarcoma Viral Oncogene Homolog B 试剂盒 (5)和数多这个蛋白质的别的产品。
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Human Polyclonal FOSB Primary Antibody for FACS, WB - ABIN1882084
Li, Fu, Wang, Tie, Xing, Zhu, Sun, Wei, Zheng: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma. in Hepatology (Baltimore, Md.) 2009
FOSB overexpression results in TNBC cell death, whereas inhibition of calcium signaling eliminates FOSB induction and blocks TP4-induced TNBC cell death
results shows the involvement of Spry2 (显示 SPRY2 抗体) in regulation of FosB and Runx2 (显示 RUNX2 抗体) genes, MAPK (显示 MAPK1 抗体) signaling and proliferation of mesenchymal stem cells.
the mechanism underlying redox-regulation of AP-1 Fos/Jun transcription factors and provide structural insight for therapeutic interventions targeting AP-1 proteins.
The NFATc3 (显示 NFATC3 抗体) first induced the expression of its interaction partner FosB before forming the heterodimeric NFATc3 (显示 NFATC3 抗体)-FosB transcription factor complex, which bound the proximal AP-1 site in the TF gene promoter and activated TF expression.
FosB expression in the prefrontal cortex and hippocampus of the cocaine addicted and depression patients
FOSB is a highly sensitive and diagnostically useful marker for pseudomyogenic hemangioendothelioma.
our findings show that DeltaFosB increases the expression of MMP-9 (显示 MMP9 抗体) and exhibits a significantly high survival and proliferation in MCF-7 cells.
Diffuse and strong FOSB expression was specific for pseudomyogenic hemangioendothelioma in the current series and FOSB immunohistochemistry is an effective tool for differentiating between PHE and its histological mimics.
Our results using a number of approaches, such as promoter reporter assay, FosB knock down and Chip assay, suggest that the expression of miR (显示 MLXIP 抗体)-22 is regulated transcriptionally by FosB.
These results suggest that SETDB1 (显示 SETDB1 抗体)- mediated FosB expression is a common molecular phenomenon, and might be a novel pathway responsible for the increase in cell proliferation that frequently occurs during anticancer drug therapy.
These findings suggest that GosB may regulate mammary epithelial cells milk fat synthesis and apoptosis via PPARgamma (显示 PPARG 抗体) in mouse mammary glands.
propose that chronic suppression of calbindin (显示 CALB1 抗体) by DeltaFosB is one mechanism through which intermittent seizures drive persistent cognitive deficits in conditions accompanied by recurrent seizures
Both CREB (显示 CREB1 抗体) and deltaFosB play a role in the induction of this behavioural sensitization.
Study investigated effects of chronic variable mild stress (CVMS) in non-injected, vehicle and imipramine-treated KO mice vs. wildtype (WT) counterparts and mapped the CVMS-related FosB response in 18 brain areas; found that PACAP (显示 ADCYAP1 抗体) deficiency affects neuronal reactivity in a brain area-specific manner in stress centers
abnormal regulation of MSK1 (显示 RPS6KA5 抗体) contributes to the development of L-DOPA-induced dyskinesia and to the concomitant increase in striatal FosB, which may occur via increased histone H3 (显示 HIST3H3 抗体) phosphorylation at the fosB promoter
The most highly stereotypic mice showed the most elevated FosB/DeltaFosB activity in the nucleus accumbens
FosB/DeltaFosB immunoreactivity was transiently increased in hippocampus and parahippocampal cortices by 6-Hz corneal stimulation. FosB induction was primarily localized in pyramidal neurons.
Histone methylation or acetylation at the Fosb locus in nucleus accumbens, was sufficient to control drug- and stress-evoked behavioral responses.
Findings demonstrate that, under excitotoxicity, Fosb products contribute to a neuroinflammatory response in the hippocampus through regulation of microglial C5ar1 (显示 C5AR1 抗体) and C5ar2 expression
These results indicate that social stress-induced behavioral deficits are mediated partly by molecular adaptations in mPFC involving DeltaFosB and CCK (显示 CCK 抗体) through cortical projections to distinct subcortical targets.
The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
FBJ murine osteosarcoma viral oncogene homolog B
, protein fosB
, G0/G1 switch regulatory protein 3
, activator protein 1
, FBJ osteosarcoma viral oncogene isoform deltaFosb-2