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ENGASE encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. 再加上，我们可以发ENGASE 试剂盒 (6) 和 ENGASE 蛋白 (3)和数多这个蛋白质的别的产品。
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In patients with autosomal dominant polycystic kidney disease, urinary NAGase was correlated with urinary ET-1 (显示 EDN1 抗体) which was inversely associated with eGFR (显示 EGFR 抗体) and positively correlated with total kidney volume.
Serological N-acetyl-glucosaminidase (显示 NAGLU 抗体), telomere length, and the UCP2 (显示 UCP2 抗体)-886G>A variant are independent risk factors for type 2 diabetes.
As the generation of the bulk of fOS is unaffected by co-down regulation of Ngly1p and Engase1p, alternative quantitatively important mechanisms must underlie the liberation of these fOS from either LLO or glycoproteins during protein N-glycosylation.
O-GlcNAcase (显示 MGEA5 抗体) expression is increased in erythrocytes from both individuals with pre-diabetes and individuals with less well-controlled diabetes.
involved in processing of free oligosaccharides in the cytosol; identification of the gene encoding human cytosolic ENGase
endo-beta-n-acetylglucosaminidase present in the synovial fluid of rheumatoid arthritis patients, may contribute to the depletion of glycosaminoglycans from cartilage allowing the invasion of synovial cells
identification of O-GlcNAcase (显示 MGEA5 抗体) as a caspase-3 (显示 CASP3 抗体) substrate with a novel caspase-3 (显示 CASP3 抗体) cleavage site and provide insight about O-GlcNAcase (显示 MGEA5 抗体) regulation during apoptosis.
These observations strongly suggest that the Ngly1 (显示 NGLY1 抗体)- or Ngly1 (显示 NGLY1 抗体)/Engase-deficient mice could serve as a valuable animal model for studies related to the pathogenesis of the NGLY1 (显示 NGLY1 抗体)-deficiency, and that cytoplasmic ENGase represents one of the potential therapeutic targets for this genetic disorder.
ENGase efficiently hydrolyzes phosphorylated oligosaccharides that are larger than Man4GlcNAc2-P, generating GlcNAc-1-P and neutral Gn1 (显示 GYG1 抗体)-type free oligosaccharides.
This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides.
, Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase
, Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
, Cytosolic endo-beta-N-acetylglucosaminidase