anti-Early Growth Response 2 (EGR2) 抗体

The protein encoded by EGR2 is a transcription factor with three tandem C2H2-type zinc fingers. 再加上,我们可以发EGR2 试剂盒 (31)EGR2 蛋白 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
EGR2 1959 P11161
EGR2 13654 P08152
EGR2 114090 P51774
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antibodies-online.cn销售最多的anti-EGR2 抗体

Showing 10 out of 119 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-EGR2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Lung Human Intestine 100 μL 2至3个工作日
$319.00
详细
山羊 非结合性 ELISA, WB ABIN334389 (0.03µg/ml) staining of HepG2 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6至7个工作日
$429.84
详细
Cow 非结合性 IHC, IHC (p), WB Human Adrenal (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN462263 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN462263 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 100 μL 11至14个工作日
$727.83
详细
Cow 山羊 非结合性 ELISA, IHC, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN461949 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN461949 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg 11至14个工作日
$484.00
详细
非结合性 IHC (fro), WB WB Image Western Blot analysis of EGR2 expression in transfected 293T cell line by EGR2 polyclonal antibody. A: Non-transfected lysate. B: EGR2 transfected lysate. 12% SDS PAGE antibody diluted at 1:500 IHC-Fr Image Immunohistochemical analysis of mouse brain tissue (paraformaldehyde-fixed frozen sections), using EGR2, antibody at 1:500 dilution. 100 μL 3至4个工作日
$466.18
详细
小鼠 非结合性 IF, WB 100 μL 11至14个工作日
$522.50
详细
山羊 非结合性 EIA, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with EGR2at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg 6至8个工作日
$495.00
详细
小鼠 非结合性 IF, IHC, IHC (p), WB 100 μL 11至14个工作日
$522.50
详细
非结合性 ELISA, IF, IHC, WB 100 μL Available
$363.46
详细
非结合性 ELISA, WB Western blot analysis on HeLa cell lysate using EGR2 Antibody,The lane on the left is treated with the antigen-specific peptide. Western blot analysis on mouse muscle lysate using EGR2 Antibody 100 μL 11至12个工作日
$390.77
详细

引用最多的anti-EGR2 抗体

  1. Cow (Bovine) Polyclonal EGR2 Primary Antibody for IHC, WB - ABIN2792631 : Yoo, Lee: Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 Pubmed References

  2. Polyclonal EGR2 Primary Antibody for WB - ABIN540733 : Harris, Ayyub, Shaw: A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. in Journal of neuroscience research 1992 (PubMed)
    Show all 2 Pubmed References

  3. Dog (Canine) Polyclonal EGR2 Primary Antibody for ELISA, WB - ABIN547955 : LeBlanc, Ward, Svaren: Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10. in Molecular and cellular biology 2007 (PubMed)

  4. Human Polyclonal EGR2 Primary Antibody for ICC, IF - ABIN258617 : Hinze, Mayer, Harst, von Kügelgen: Adenosine A(3) receptor-induced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes. in Journal of molecular and cellular cardiology 2012 (PubMed)

更多抗EGR2的相互作用对抗体

Human Early Growth Response 2 (EGR2) interaction partners

  1. In Greek Charcot-Marie-Tooth type 1 patients, 3 pathogenic mutations were found (3.5%); two recently reported micromutations in PMP22 3, and one known point mutation in EGR2

  2. LAG3(+) Tregs suppress humoral immune responses via transforming growth factor beta3 production in an Egr2- and Egr3-dependent manner.

  3. Low EGR2 expression is associated with hepatocellular carcinoma.

  4. The study suggests that acetylation of EGR2 is regulated independently of nucleosome remodeling and deacetylase.

  5. Egr2-driven cell surface proteins LAG-3 and 4-1BB can identify dysfunctional tumor antigen-specific CD8(+) TIL.

  6. Egr2 and Egr3 have emerged as regulatory molecules that suppress excessive immune responses. Mice deficient for Egr2 and Egr3 develop a lupus-like disease with dysregulated activation of effector T cells. Egr2 and Egr3 confer suppressive activity to CD4(+) T cells and regulate the production of inhibitory cytokines such as IL-10 and TGF-beta1.

  7. Analysis of consensus EGR-binding elements (EBEs) showed that the immediate early response 3 gene (IER3) is a novel transcriptional target gene of EGR2 as confirmed by the luciferase assay, electrophoretic mobility-shift assay (EMSA), chromatin immunoprecipitation (ChIP), and western blot analysis.

  8. In the PPI network, genes may be involved in Down syndrome (DS) by interacting with others, including nuclear receptor subfamily 4 group A member 2 (NR4A2)early growth response (EGR)2 and NR4A2EGR3. Therefore, RUNX1, NR4A2, EGR2, EGR3 and ID4 may be key genes associated with the pathogenesis of DS.

  9. EGR2 mutation presents as an axonal Charcot-Marie-Tooth phenotype with variable severity.

  10. MicroRNA20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing EGR2 expression.

  11. These results suggested that EGR2 overexpression has a pivotal role in the downregulation of cytokines implicated in the pathophysiology of Guillain-Barre syndrome

  12. A recurrent mutation was identified in EGR2 which appears to be associated with the pathogenesis of schizophrenia.

  13. Knock-down of EGR2 with siRNA was demonstrated to have a similar effect as the over-expression of miR-330-3p in NSCLC cell lines

  14. Dysregulated Egr-2 is observed in some human autoimmune disorders.

  15. EGR2 knockdown inhibited proliferation, clonogenicity and spheroidal growth in vitro and induced regression of Ewing sarcoma xenografts.

  16. our data suggest that robust CD26 costimulatory signaling induces preferential expression of EGR2 and IL-10 as a potential mechanism for regulating CD26-mediated activation.

  17. transcription factor early growth response gene-2 is a novel molecular switch regulating known immunomodulatory molecules in human mesenchymal stem cells.

  18. Overexpression of EGR2 significantly attenuated the oncogenic effect of miR-20a.

  19. Lack of association of EGR2 variants with bipolar disorder in Japanese population.

  20. EGR2 and EGR3 are regulated by NFkappaB and MAPK signalling pathways downstream of TNFalpha stimulation in breast adipose fibroblasts, and this in turn is upstream of CYP19A1 transcription via PI.4

Mouse (Murine) Early Growth Response 2 (EGR2) interaction partners

  1. Egr2 was critical for the expression of transcription factors CEBPbeta and PPARgamma in M2 macrophages, and CEBPbeta was highly expressed in M1-polarized macrophages.

  2. miR-138 is an Egr2-dependent microRNA but is dispensable for Schwann cell myelination

  3. data reveal a regulatory circuit involving Egr2-Id3-E2A, which normally restricts the population size of gammadelta NKT cells by adjusting Egr2 dosage and c-Myc expression.

  4. Study findings demonstrated that despite impaired proliferation and IL2 production, tolerant T cells can display inflammatory responses in response to antigen stimulation and this is controlled at least partly by Egr2 and Egr3.

  5. Egr2 may play an important role during embryo implantation and decidualization in the mouse.

  6. Study shows the conversion of mouse skin fibroblasts into induced Schwann cells by driving the expression of two transcription factors, Sox10 and Egr2.

  7. Egr2 and Egr3 expressed in T cells cooperatively prevent humoral immune responses by supporting TGF-beta3 secretion.

  8. study revealed GCN5-mediated EGR2 acetylation as a molecular mechanism that regulates iNKT development.

  9. findings demonstrate a crucial role for Krox20 in arterial valve development and reveal that an excess of neural crest cells may be associated with bicuspid aortic valve.

  10. these results suggested that the basal promoter activity of the mIRF-3 gene is regulated by transcription factors Egr2 and YY1 in NIH3T3 cells

  11. Prss56 expression was regulated by Egr2 during mouse decidualization.

  12. Egr2 and 3 are upstream regulators of effector CD4 and CD8 T cells that are essential for optimal responses with limited immunopathology.

  13. Egr2 and 3 are antagonists of T-bet function in effector T cells and are important for the control of inflammatory responses of T cells.

  14. We discovered that Tead1 and co-activators Yap and Taz are required for Pmp22 expression, as well as for the expression of Egr2 Tead1 directly binds Pmp22 and Egr2 enhancers early in development and Tead1 binding is induced during myelination, correlating with Pmp22 expression. The data identify Tead1 as a novel regulator of Pmp22 expression during development in concert with Sox10 and Egr2

  15. endogenous KLF4 and Krox20 are dispensable for adipogenesis in culture and for brown adipose tissue development in mice. In contrast, the master adipogenic transcription factor peroxisome proliferator-activated receptor gamma (PPARgamma) is essential.

  16. Decreased expression of Krox20 in mice causes degeneration of the aortic leaflets and disorganization of the extracellular matrix, causing valvular dysfunction.

  17. Mir106b regulates pro-allergic properties of dendritic cells and Th2 polarisation by targeting Egr-2 in vitro

  18. let-7 miRNAs promote expression of the myelination-driving master transcription factor Krox20

  19. The data suggest that Pak2 controls thymic Natural Killer T-cell development by providing a signal that links Egr2 to induce PLZF, in part by regulating signaling lymphocyte activation molecule 6 expression.

  20. demonstrate a novel function of EGR2/3 that is important for Tfh cell development and Tfh cell-mediated B cell immune responses

Zebrafish Early Growth Response 2 (EGR2) interaction partners

  1. We performed a global analysis of the cis-acting elements involved in the control of the zebrafish developmental gene krox20. krox20 encodes a transcription factor required for hindbrain segmentation and patterning, a morphogenetic process highly conserved during vertebrate evolution.

  2. A direct, positive autoregulatory loop amplifies and maintains the expression of Krox20, a transcription factor governing vertebrate hindbrain segmentation.

  3. Hindbrain patterning requires fine-tuning of early krox20 transcription by Sprouty 4.

  4. Data show that Irx7 and Irx1b are required for the proper formation and specification of rhombomeres 1 to 4, and that Irx7 functionally interacts with Meis1.1 to activate the expression of anterior hindbrain markers, such as krox20.

EGR2 抗原简介

蛋白简介

The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with EGR2

  • early growth response 2 (EGR2) 抗体
  • early growth response 2 (Egr2) 抗体
  • early growth response 2b (egr2b) 抗体
  • AT591 抗体
  • cb427 抗体
  • CMT1D 抗体
  • CMT4E 抗体
  • Egr-2 抗体
  • egr2 抗体
  • id:ibd5073 抗体
  • Krox-20 抗体
  • krox20 抗体
  • KRX-20 抗体
  • krx20 抗体
  • NGF1-B 抗体
  • wu:fb71h10 抗体
  • Zfp-6 抗体
  • Zfp-25 抗体
  • zgc:92210 抗体

Protein level used designations for EGR2

E3 SUMO-protein ligase EGR2 , KROX-20, Drosophila, homolog (early growth response-2) , early growth response protein 2 , zinc finger protein Krox-20 , early growth response 2 (Krox-20 homolog, Drosophila) , EGR-2 , EGR-2b , early growth response protein 2b , krox-20 , protein krx-20

GENE ID SPECIES
1959 Homo sapiens
479219 Canis lupus familiaris
100038004 Sus scrofa
13654 Mus musculus
114090 Rattus norvegicus
100721167 Cavia porcellus
100297981 Bos taurus
101122407 Ovis aries
30190 Danio rerio
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