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DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. 再加上，我们可以发DNAJC6 蛋白 (4)和数多这个蛋白质的别的产品。
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Cow (Bovine) Polyclonal DNAJC6 Primary Antibody for ELISA, ICC - ABIN4305630
Seki, Ohira, Nagase, Ishikawa, Miyajima, Nakajima, Nomura, Ohara: Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. in DNA research : an international journal for rapid publication of reports on genes and genomes 1998
DNAJC6 mutations are not common causes of early onset Parkinson's disease in Chinese population
DNAJC6 mutations are associated with early-onset Parkinson's disease.
DNAJC6 is up-regulated in hepatocellular carcinoma tissues and up-regulation of DNAJC6 expression predicts poor outcome in patients with HCC (显示 FAM126A 抗体)
Missense mutations in DNAJC6 does not play a major role in PD in the Chinese population.
we did not detect any heterozygous or homozygous c.801-2A>G mutation in DNAJC6 in a cohort of Parkinson disease patients from southern Spain.
This review presented that DNAJC6 in recessive forms of juvenile parkinsonism.
Our findings further establish DNAJC6 as a juvenile parkinsonism gene, and expand the spectrums of the parkinsonism phenotype and DNAJC6 mutation
study reports a homozygous mutation in DNAJC6 in two patients with autosomal-recessive juvenile Parkinsonism; the mutation was associated with abnormal transcripts and marked reduced DNAJC6 mRNA level
The DNAJC6 gene encodes auxilin-1, a protein required for clathrin-dependent recycling of synaptic vesicles in neurons that is possibly at the origin of the mental retardation and epilepsy phenotype
there are two auxilins with overlapping functions; they not only facilitate the uncoating of clathrin-coated vesicles but also prevent the formation of nonproductive clathrin cages in the cytosol
Data suggest that anionic lipids (such as phosphatidylinositol phosphates) play crucial role in localization of peripheral membrane proteins (such as auxilin-1, PTEN [phosphatase and tensin homolog], and talin-1 (显示 TLN1 抗体)). [review-like article]
Structure of clathrin coat with bound Hsc70 (显示 HSPA8 抗体) and auxilin.
Auxilin binding produces a local change in heavy-chain contacts, creating a detectable global distortion of the clathrin coat [auxilin]
timing of auxilin recruitment determines the onset of uncoating
Results describe the recruitment dynamics of GAK and auxilin to clathrin-coated pits during endocytosis.
Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin-dependent, Hsc70 (显示 HSPA8 抗体)-catalyzed uncoating.
DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000
DnaJ (Hsp40) homolog, subfamily B, member 6
, dnaJ homolog subfamily C member 6
, putative tyrosine-protein phosphatase auxilin