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anti-DTL 抗体

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis.

44 results:

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) (C-Term) Primary Antibody

DTL 适用: 人, 小鼠 FACS, IF, IP, WB 宿主: 兔 Polyclonal
产品编号 ABIN2451940
$500.00
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
9至11个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) (AA 229-256) Primary Antibody

DTL 适用: 人, 小鼠 EIA, FACS, WB 宿主: 兔 Polyclonal
Pubmed 1
产品编号 ABIN951451
$539.00
加上运输费 $45.00
0.4 mL
local_shipping 发货至: 美国
6至8个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) (AA 1-730) Primary Antibody

DTL 适用: 人 IF, WB 宿主: 兔 Polyclonal
产品编号 ABIN949333
$425.71
加上运输费 $45.00
100 μg
local_shipping 发货至: 美国
11至12个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) (AA 229-256) Primary Antibody

DTL 适用: 人, 小鼠 FACS, WB 宿主: 兔 Polyclonal
产品编号 ABIN5538456
$570.63
加上运输费 $45.00
400 μL
local_shipping 发货至: 美国
2至3个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) Primary Antibody

DTL 适用: 人, 小鼠 FACS, WB 宿主: 兔 Polyclonal
产品编号 ABIN2995947
$660.00
加上运输费 $45.00
400 μL (More quantities available)
local_shipping 发货至: 美国
11至16个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) Primary Antibody

DTL 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal
产品编号 ABIN630978
$647.32
加上运输费 $45.00
50 μg
local_shipping 发货至: 美国
9至11个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) (N-Term) Primary Antibody

DTL 适用: Cow, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal
产品编号 ABIN2782560
$229.00
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
2至3个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) (AA 182-231) Primary Antibody

DTL 适用: Bat, Cow, 犬, 豚鼠, 马, 人, 猴, 小鼠, Pig, 兔, 大鼠 WB 宿主: 兔 Polyclonal
产品编号 ABIN6738232
$551.83
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
11至14个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) Primary Antibody

DTL 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal
产品编号 ABIN6390479
$352.27
加上运输费 $45.00
100 μL (More quantities available)
local_shipping 发货至: 美国
11至13个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) Primary Antibody

DTL 适用: 人 WB 宿主: 兔 Polyclonal
产品编号 ABIN6139847
$589.88
加上运输费 $45.00
100 μL (More quantities available)
local_shipping 发货至: 美国
13至14个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) (N-Term) Primary Antibody

DTL 适用: 人 WB 宿主: 兔 Polyclonal
产品编号 ABIN2442043
$318.55
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
2至3个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) Primary Antibody

DTL 适用: 人, 小鼠, 大鼠 IF (p), IHC (p), WB 宿主: 兔 Polyclonal
产品编号 ABIN873173
$339.90
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
4至6个工作日

anti-DTL 抗体 (Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila)) Primary Antibody

DTL 适用: 人, 小鼠, 大鼠 ELISA, IP, WB 宿主: 兔 Polyclonal
产品编号 ABIN5705388
$380.00
加上运输费 $45.00
100 μg
local_shipping 发货至: 美国
13至16个工作日
产品编号 ABIN6825660
$438.90
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
6至8个工作日
产品编号 ABIN6841723
$438.90
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
6至8个工作日
  • 类型 Primary
    • Primary
  • 抗原 Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila) (DTL)
    • Denticleless E3 Ubiquitin Protein Ligase Homolog (Drosophila) (DTL)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4 Molecule (CD4)
    • tau Protein
    • Tumor Necrosis Factor alpha (TNF)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Estrogen Receptor 1 (ESR1)
    • Albumin (ALB)
    • Interferon gamma (IFNG)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Nuclear Factor-KB P65 (NFkBP65)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • CD44
    • CD19 Molecule (CD19)
    • Amyloid beta (A4) Precursor Protein (APP)
    • Tuberous Sclerosis 2 (TSC2)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • CD8a Molecule (CD8A)
    • Integrin alpha M (ITGAM)
    • Myc Proto-Oncogene protein (MYC)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Hemagglutinin (HA)
    • CD8
    • Histone H4
    • Interleukin 6 (IL6)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Jun Proto-Oncogene (JUN)
    • Vimentin (VIM)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • CD5 Molecule (CD5)
    • CD3
    • Mucin 1, Cell Surface Associated (MUC1)
    • Glial Fibrillary Acidic Protein (GFAP)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Synuclein, alpha (SNCA)
    • CD34
    • Interleukin 2 (IL2)
    • CD14
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • Cyclin-Dependent Kinase 1 (CDK1)
    • Androgen Receptor (AR)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • Activating Transcription Factor 2 (ATF2)
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Flow Cytometry (FACS)
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Enzyme Immunoassay (EIA)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 适用
    • 小鼠
    • 大鼠
    • Cow
    • 豚鼠
    • Bat
    • Pig
  • 论文引用
  • 图像
  • 抗体来源
    • 小鸡
  • 克隆形成能力
    • Polyclonal
  • 抗原表位
    • AA 229-256
    • Center
    • Internal Region
    • AA 393-550
    • AA 1-730
    • C-Term
    • N-Term
    • AA 1-196
    • AA 182-231
    • AA 375-425
    • AA 680-730
    • Middle Region
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
    • APC
    • Alkaline Phosphatase (AP)
    • PE
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
  • 抗体亚型
    • IgG
    • Ig Fraction
  • Format
    • Liquid
    • Lyophilized

DTL 抗原简介

蛋白简介

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. Most substrates require their interaction with PCNA for PIP-box, and those containing the 'K+4' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the 'Lys-164' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis (By similarity).

Gene names and symbols associated with DTL

  • denticleless E3 ubiquitin protein ligase homolog (DTL) 抗体
  • denticleless E3 ubiquitin protein ligase (Dtl) 抗体
  • denticleless E3 ubiquitin protein ligase homolog (Dtl) 抗体
  • denticleless E3 ubiquitin protein ligase homolog S homeolog (dtl.S) 抗体
  • denticleless E3 ubiquitin protein ligase homolog (Drosophila) (dtl) 抗体
  • 2810047L02Rik 抗体
  • 5730564G15Rik 抗体
  • cb151 抗体
  • cdt2 抗体
  • cdt2-a 抗体
  • chunp6871 抗体
  • dcaf2 抗体
  • l2dtl 抗体
  • ramp 抗体
  • RGD1310439 抗体
  • wu:fb54b02 抗体

Protein level used designations for DTL

DDB1 and CUL4 associated factor 2 , DDB1- and CUL4-associated factor 2 , RA regulated nuclear matrix associated protein , RA-regulated nuclear matrix-associated protein , denticleless homolog , denticleless protein homolog , lethal(2) denticleless protein homolog , retinoic acid-regulated nuclear matrix-associated protein , Meth A ramp , meth A retinoic acid-regulated nuclear matrix-associated protein , retinoic-acid regulated nuclear matrix-associated protein , denticleless protein homolog A

GENE ID SPECIES
51514 Homo sapiens
76843 Mus musculus
305073 Rattus norvegicus
490279 Canis lupus familiaris
421373 Gallus gallus
735103 Xenopus laevis
539953 Bos taurus
100723475 Cavia porcellus
192314 Danio rerio

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