anti-Deleted in Azoospermia 1 (DAZ1) 抗体

DAZ1 is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). 再加上,我们可以发DAZ1 蛋白 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
DAZ1 1617 Q9NQZ3
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antibodies-online.cn销售最多的anti-DAZ1 抗体

Showing 10 out of 63 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-DAZ1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Jurkat cell lysate 100 μL 2至3个工作日
Cow 非结合性 WB 100 μL 11至14个工作日
小鼠 非结合性 IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to DAZ1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1 ug/ml] DAZ1 monoclonal antibody (M06), clone 3E3. Western Blot analysis of DAZ1 expression in Daoy. 100 μg 11至12个工作日
小鼠 非结合性 IF, IHC (p), ELISA, WB DAZ1 monoclonal antibody (M01), clone 3G10. Western Blot analysis of DAZ1 expression in human pancreas. Immunoperoxidase of monoclonal antibody to DAZ1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1 ug/ml] 100 μg 11至12个工作日
小鼠 非结合性 EIA, IF, IHC (p), WB 50 μg 6至8个工作日
小鼠 非结合性 ELISA, IHC, IHC (p), WB 100 μg 11至14个工作日
小鼠 非结合性 ELISA, IF, IHC, IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11至14个工作日
非结合性 WB DAZ1 antibody used at 1 ug/ml to detect target protein. 50 μg 9至11个工作日
小鼠 非结合性 ELISA, WB DAZ1 monoclonal antibody (M04), clone 4F3. Western Blot analysis of DAZ1 expression in human placenta. Detection limit for recombinant GST tagged DAZ1 is approximately 1ng/ml as a capture antibody. 100 μg 11至12个工作日
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11至12个工作日

引用最多的anti-DAZ1 抗体

  1. Cow (Bovine) Polyclonal DAZ1 Primary Antibody for WB - ABIN2787798 : Stouffs, Tournaye, Van der Elst, Haentjens, Liebaers, Lissens: Do we need to search for gr/gr deletions in infertile men in a clinical setting? in Human reproduction (Oxford, England) 2008 (PubMed)


Human Deleted in Azoospermia 1 (DAZ1) interaction partners

  1. There was an increased frequency of DAZ microdeletion in blood samples from oligozoospermic and near azoospermic patients. A high frequency of DAZ microdeletion was observed in the sperm of patients with no DAZ microdeletion in their leukocytes compared to control. The results might be indicative of DAZ microdeletion induction during spermatogenesis.

  2. We investigated partial deletion of AZFc region and DAZ copy number in a population of Iranian infertile men and normozoospermic controls.

  3. Susceptibility of gr/gr rearrangements to azoospermia or oligozoospermia is dependent on DAZ and CDY1 gene copy deletions.

  4. Overexpression of DAZ1 is associated with breast tumors.

  5. Studies indicate that partial RNA-binding proteins DAZ1/2 deletion was associated wih male infertility, but partial RNA-binding proteins DAZ3/4 deletion was not associated with male infertility.

  6. We did not found any statistically significant genetic association between DAZ alleles and idiopathic male infertility

  7. genetic association study in Chinese population: Data suggest that combined patterns of copy number abnormality in DAZ1 (deleted in azoospermia 1) and/or BPY2 (basic charge Y-linked protein 2) are associated with spermatogenic impairment/azoospermia.

  8. There appears to be an asociation of DAZ1/DAZ2 deletion with spermatogenic impairment and male infertility in the South Chinese population.

  9. Report the prevalence of variations in the AZFc region of the human Y chromosome in infertile men.

  10. genetic association studies in Han population in China: Data suggest that AZF1/DAZ1 duplications underlie genetic predisposition of Y-chromosome haplogroup K* to spermatogenic impairment (azoospermia/oligospermia) in the population studied.

  11. The methylation patterns of CpG island (CGI) in the DAZ gene promoter region were different between somatic cells and spermatic cells

  12. role in male infertility - review

  13. altered transcription in azoospermia

  14. DAZ gene copy number in severely idiopathic infertile men. Gene deletion of two copies of DAZ (DAZI and 2) was the cause of spermatogenic damage.

  15. Sertoli cell function is not damaged in patients with AZFc-DAZ deletions and that the strong reduction of germ cells does not affect the FSH-inhibin B feedback loop.

  16. DAZ/DAZL protein can form a stable complex with human PUM2.

  17. Loss of only some copies of DAZ is sufficient to lead to severe male infertility, but it is not a frequent finding in cryptorchid men.

  18. Role in spermatogenesis. Decreased DAZ proteins in spermatogenic failure may be due to germ cell loss. Transcription of BOULE, DAZL, and DAZ not altered in degrees of spermatogenic failure. No increase of DAZL or BOULE found in DAZ deletion.

  19. The deleted in azoospermia (DAZ) are believed to have important function in sperm production, since DAZ is frequently deleted in azoospermic and severy oligozoospermic men.

  20. The frequency of partial copy deletion of DAZ gene in Chinese idiopathic azoospermia or severe oligozoospermia patients is much higher, suggesting that the deletion of DAZ1/DAZ2 may be one of the important factors of spermatogenesis damage.

DAZ1 抗原简介


This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications\; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat\; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified\; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described\; thus the RefSeq for this gene contains only two RRM domains.

Gene names and symbols associated with DAZ1

  • deleted in azoospermia protein 1 (LOC749905) 抗体
  • deleted in azoospermia 1 (DAZ1) 抗体
  • DAZ 抗体
  • DAZ1 抗体
  • DAZ4 抗体
  • SPGY 抗体

Protein level used designations for DAZ1

deleted in azoospermia 1 , DAZ protein , deleted in azoospermia 4 , deleted in azoospermia protein 1

749905 Pan troglodytes
1617 Homo sapiens
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