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DAXX 抗体

(Death-Domain Associated Protein (DAXX))
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008].
DAXX 抗体  (AA 561-660) DAXX 抗体  (AA 561-660) DAXX 抗体 (AA 561-660) (ABIN514879)

DAXX 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4C2 unconjugated

DAXX 抗体  (AA 558-740) DAXX 抗体  (AA 558-740) DAXX 抗体 (AA 558-740) (ABIN94302)

DAXX 适用: 人 WB, ICC 宿主: 小鼠 Monoclonal DAXX-01 unconjugated

DAXX 抗体 DAXX 抗体 DAXX 抗体 (ABIN969493)

DAXX 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7A11 unconjugated

DAXX 抗体 by 适用

Find DAXX 抗体 for a variety of species such as anti-Human DAXX, anti-Rat DAXX, anti-Mouse DAXX. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find DAXX 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find DAXX 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

DAXX 抗体 by 克隆形成能力

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DAXX 抗体 by 克隆

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Find DAXX 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular DAXX 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, PLA
Validations
  • (5)
Cat. No. ABIN514879
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN94302
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, ICC
Validations
  • (4)
Cat. No. ABIN969493
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN3043822
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6261227
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN5576429
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, EIA
Validations
  • (4)
Cat. No. ABIN1106953
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN757627
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN757672
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN514878
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5649900
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IP
Validations
  • (1)
  • (1)
Cat. No. ABIN302079
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, IHC, IF, IP, IC
Validations
  • (3)
Cat. No. ABIN7295480
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
  • (1)
Cat. No. ABIN1713620
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Validations
  • (1)
Cat. No. ABIN757687
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our DAXX 抗体

Yang, Hu, Chen, Zhu, Li, Lu, Li, Dong: "Necrostatin-1 protects hippocampal neurons against ischemia/reperfusion injury via the RIP3/DAXX signaling pathway in rats." in: Neuroscience letters, Vol. 651, pp. 207-215, (2017) (PubMed).

Pipinikas, Dibra, Karpathakis, Feber, Novelli, Oukrif, Fusai, Valente, Caplin, Meyer, Teschendorff, Bell, Morris, Salomoni, Luong, Davidson, Beck, Thirlwell: "Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours." in: Endocrine-related cancer, Vol. 22, Issue 3, pp. L13-8, (2015) (PubMed).

Fishbein, Khare, Wubbenhorst, DeSloover, DAndrea, Merrill, Cho, Greenberg, Else, Montone, LiVolsi, Fraker, Daber, Cohen, Nathanson: "Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas." in: Nature communications, Vol. 6, pp. 6140, (2015) (PubMed).

Napier, Huschtscha, Harvey, Bower, Noble, Hendrickson, Reddel: "ATRX represses alternative lengthening of telomeres." in: Oncotarget, Vol. 6, Issue 18, pp. 16543-58, (2015) (PubMed).

Yoshida, Ogawa, Yoshida, Maeshima, Kanai, Kinoshita, Hiraoka, Sekine: "TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast." in: British journal of cancer, Vol. 113, Issue 8, pp. 1244-8, (2015) (PubMed).

Weisbrod, Zhang, Jain, Barak, Quezado, Kebebew: "Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors." in: Hormones & cancer, Vol. 4, Issue 3, pp. 165-75, (2013) (PubMed).

Stepp, Meyers, McBride: "Sp100 provides intrinsic immunity against human papillomavirus infection." in: mBio, Vol. 4, Issue 6, pp. e00845-13, (2013) (PubMed).

Schwartzentruber, Korshunov, Liu, Jones, Pfaff, Jacob, Sturm, Fontebasso, Quang, Tönjes, Hovestadt, Albrecht, Kool, Nantel, Konermann, Lindroth, Jäger, Rausch, Ryzhova, Korbel, Hielscher, Hauser et al.: "Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. ..." in: Nature, Vol. 482, Issue 7384, pp. 226-31, (2012) (PubMed).

de Wilde, Heaphy, Maitra, Meeker, Edil, Wolfgang, Ellison, Schulick, Molenaar, Valk, Vriens, Borel Rinkes, Offerhaus, Hruban, Matsukuma: "Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 25, Issue 7, pp. 1033-9, (2012) (PubMed).

Heaphy, de Wilde, Jiao, Klein, Edil, Shi, Bettegowda, Rodriguez, Eberhart, Hebbar, Offerhaus, McLendon, Rasheed, He, Yan, Bigner, Oba-Shinjo, Marie, Riggins, Kinzler, Vogelstein, Hruban, Maitra et al.: "Altered telomeres in tumors with ATRX and DAXX mutations. ..." in: Science (New York, N.Y.), Vol. 333, Issue 6041, pp. 425, (2011) (PubMed).

Aliases for DAXX 抗体

death domain associated protein (DAXX) 抗体
Fas death domain-associated protein (Daxx) 抗体
28S ribosomal protein S29, mitochondrial (LOC100226911) 抗体
death-domain associated protein (Daxx) 抗体
death domain associated protein (Daxx) 抗体
death-associated protein 6 L homeolog (daxx.L) 抗体
death-domain associated protein (daxx) 抗体
BING2 抗体
DAP6 抗体
daxx 抗体
EAP1 抗体
LOC100226911 抗体
si:dz179b20.7 抗体
wu:fd15c03 抗体
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