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DAZ1 抗体 (N-Term)

DAZ1 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 山羊, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787798
发货至: 中国
  • 抗原 See all DAZ1 抗体
    DAZ1 (Deleted in Azoospermia 1 (DAZ1))
    抗原表位
    • 15
    • 7
    • 3
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, 马, 犬, 山羊, Pig, 兔
    宿主
    • 24
    • 4
    克隆类型
    • 25
    • 3
    多克隆
    标记
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DAZ1 antibody is un-conjugated
    应用范围
    • 21
    • 14
    • 13
    • 13
    • 9
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    MSAANPETPN STISREASTQ SSSAAASQGW VLPEGKIVPN TVFVGGIDAR
    预测反应
    Cow: 100%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 85%, Rat: 79%
    产品特性
    This is a rabbit polyclonal antibody against DAZ1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human DAZ1
    Top Product
    Discover our top product DAZ1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 579 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Stouffs, Tournaye, Van der Elst, Haentjens, Liebaers, Lissens: "Do we need to search for gr/gr deletions in infertile men in a clinical setting?" in: Human reproduction (Oxford, England), Vol. 23, Issue 5, pp. 1193-9, (2008) (PubMed).

  • 抗原
    DAZ1 (Deleted in Azoospermia 1 (DAZ1))
    别名
    DAZ1 (DAZ1 产品)
    别名
    DAZ1 antibody, DAZ4 antibody, DAZ antibody, SPGY antibody, deleted in azoospermia protein 1 antibody, deleted in azoospermia 1 antibody, LOC749905 antibody, DAZ1 antibody
    背景
    DAZ1 is a RNA-binding protein that plays an essential role in spermatogenesis. DAZ1 may act by binding to the 3'-UTR of mRNAs and regulating their translation.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described, thus the RefSeq for this gene contains only two RRM domains. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DAZ, SPGY
    Protein Interaction Partner: DZIP1L, BOLL, PUM2, DZIP1, QKI, DAZL, UBC, DAZ1, DZIP3, DAZAP2, DAZAP1, DYNLL1,
    Protein Size: 579
    分子量
    64 kDa
    基因ID
    1617
    NCBI登录号
    NM_004081, NP_004072
    UniProt
    Q9NQZ3
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