anti-Dedicator of Cytokinesis 2 (DOCK2) 抗体

The protein encoded by DOCK2 belongs to the CDM protein family. 再加上,我们可以发和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
DOCK2 94176 Q8C3J5
DOCK2 1794 Q92608
DOCK2 360509  
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antibodies-online.cn销售最多的anti-DOCK2 抗体

Showing 10 out of 54 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-DOCK2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: THP-1 cell lysate 100 μL Log in to see 2至3个工作日
$319.00
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 ELISA, ICC, IF, WB Western blot analysis of DOCK2 using HepG2 whole cell lysates ABIN6278392 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Log in to see 11至12个工作日
$390.77
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: DOCK2 Antibody [NBP2-38303] - Immunofluorescent staining of human cell line U-251 MG shows positivity in nucleus but excluded from the nucleoli. Immunohistochemistry: DOCK2 Antibody [NBP2-38303] - Staining of human lymph node shows strong cytoplasmic positivity in germinal and non-germinal center cells. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded mouse intestine labeled with Anti-DOCK2 Polyclonal Antibody, Unconjugated (ABIN1714521) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14至21个工作日
$306.90
详细
非结合性 WB All lanes : Anti-DOCK2 Antibody (C-term) at 1:1000 dilution Lane 1: Jurkat whole cell lysates Lane 2: Raji whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 212 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:1000 80 μL Log in to see 10至11个工作日
$120.00
详细
小鼠 非结合性 IHC, IHC (p)   100 μL Log in to see 7至9个工作日
$507.83
详细
小鼠 非结合性 IHC, IHC (p), WB   100 μL Log in to see 7至9个工作日
$507.83
详细
非结合性 ELISA, IHC   100 μL Log in to see 16 Days
$181.73
详细
非结合性 WB   100 μg Log in to see 11至14个工作日
$969.83
详细

更多抗DOCK2的相互作用对抗体

Mouse (Murine) Dedicator of Cytokinesis 2 (DOCK2) interaction partners

  1. DOCK2 deficiency protects mice from HFD-induced obesity

  2. findings showed that DOCK2-driven T cell motility was required to detach from pMHC(low) dendritic cells (DCs)and to find rare presenting peptide-MHCs (pMHCs)(high) DCs.

  3. DOCK2 is a potential therapeutic target for novel AML (显示 RUNX1 抗体) treatments, as this protein regulates the survival of leukemia cells with elevated FLT3 (显示 FLT3 抗体) activity and sensitizes FLT3 (显示 FLT3 抗体)/ITD leukemic cells to conventional antileukemic agents.

  4. Identify DOCK2 as a novel regulator for smooth muscle cell phenotypic modulation and vascular lesion formation after vascular injury.

  5. DOCK2 is critical for graft facilitating cells to maintain its immunomodulatory function.

  6. together with DOCK5 (显示 Dock5 抗体) contributes to chemotaxis, reactive oxygen species production, and extracellular trap formation

  7. the IRF5 (显示 IRF5 抗体) (-/-) mice with the DOCK2 mutation have higher serum levels of IgG1 and lower levels of IgG2b, IgG2a/c and IgG3 than IRF5 (显示 IRF5 抗体) (-/-) mice without the DOCK2 mutation, suggesting that the DOCK2 mutation confers additional Th2-type effects.

  8. findings reveal a previously unknown, nonredundant role for Elmo1 (显示 ELMO1 抗体) in controlling Dock2 levels and Dock2-dependent T cell migration in primary lymphocytes.

  9. DOCK2, an atypical guanine nucleotide exchange factor (显示 ARHGEF12 抗体) for Rac (显示 AKT1 抗体), plays a key role in NK cell-mediated cytotoxicity.

  10. in vivo results presented here suggest DOCK2 contributes to amyloid beta plaque burden via regulation of microglial innate immune function and may represent a novel therapeutic target for Alzheimer's disease

Human Dedicator of Cytokinesis 2 (DOCK2) interaction partners

  1. demonstrated that CPP-conjugation approach is applicable to the development of novel anti-inflammatory drugs based on DOCK2 inhibition by investigating both cellular uptake and bioactivity

  2. DOCK2 is a potential therapeutic target for novel AML (显示 RUNX1 抗体) treatments, as this protein regulates the survival of leukemia cells with elevated FLT3 (显示 FLT3 抗体) activity and sensitizes FLT3 (显示 FLT3 抗体)/ITD leukemic cells to conventional antileukemic agents.

  3. Brazilian Amerindian ancestry compared to Asian, European, and African Genomes.SNPs within or proximal to CIITA (显示 CIITA 抗体) (rs6498115), SMC6 (显示 SMC6 抗体) (rs1834619), and KLHL29 (rs2288697) were most differentiated in the Amerindian-specific branch. SNPs in ADAMTS9 (显示 ADAMTS9 抗体) (rs7631391), DOCK2 (rs77594147), SLC28A1 (显示 SLC28A1 抗体) (rs28649017), ARHGAP5 (显示 ARHGAP5 抗体) (rs7151991), and CIITA (显示 CIITA 抗体) (rs45601437) in the Asian comparison.

  4. Autosomal recessive DOCK2 deficiency is a new mendelian disorder with pleiotropic defects of hematopoietic and nonhematopoietic immunity.

  5. findings reveal a previously unknown, nonredundant role for Elmo1 (显示 ELMO1 抗体) in controlling Dock2 levels and Dock2-dependent T cell migration in primary lymphocytes.

  6. DOCK2 is required for the normal T and B cell migration and signal transduction. (Review)

  7. DOCK2 mutations are associated with esophageal adenocarcinoma.

  8. The C-terminal Pro-rich tail of ELMO1 (显示 ELMO1 抗体) winds around the Src (显示 SRC 抗体)-homology 3 domain of DOCK2 to form an intermolecular 5-helix bundle. The entire regions of both DOCK2 a& ELMO1 (显示 ELMO1 抗体) assemble to create a rigid structure required for the DOCK2 & ELMO1 (显示 ELMO1 抗体) binding.

  9. Our results show CXCL13 (显示 CXCL13 抗体)-mediated PCa (显示 FLVCR1 抗体) cell invasion requires Akt (显示 AKT1 抗体) and ERK12 activation and suggests a new role for DOCK2 in proliferation of hormone-refractory CXCR5 (显示 CXCR5 抗体)-positive PCa (显示 FLVCR1 抗体) cells.

  10. prostate cancer cell lines differentially express phosphoinositide-3 kinase (PI3K (显示 PIK3CA 抗体)) catalytic subunit isoforms and dedicator of cytokinesis 2

DOCK2 抗原简介

蛋白简介

The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection.

Gene names and symbols associated with DOCK2

  • dedicator of cytokinesis 2 (DOCK2) 抗体
  • dedicator of cytokinesis 2 (dock2) 抗体
  • dedicator of cyto-kinesis 2 (Dock2) 抗体
  • dedicator of cytokinesis 2 (Dock2) 抗体
  • AI662014 抗体
  • AW122239 抗体
  • CED-5 抗体
  • Hch 抗体
  • MBC 抗体

Protein level used designations for DOCK2

dedicator of cytokinesis 2 , dedicator of cytokinesis protein 2-like , dedicator of cytokinesis protein 2 , dedicator of cyto-kinesis 2

GENE ID SPECIES
427612 Gallus gallus
471731 Pan troglodytes
100070446 Equus caballus
100231624 Taeniopygia guttata
100512021 Sus scrofa
100558131 Anolis carolinensis
94176 Mus musculus
1794 Homo sapiens
360509 Rattus norvegicus
489128 Canis lupus familiaris
510083 Bos taurus
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