anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) 抗体

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. 再加上,我们可以发DDX41 试剂盒 (10)DDX41 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
DDX41 51428 Q9UJV9
DDX41 72935 Q91VN6
DDX41 314336  
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antibodies-online.cn销售最多的anti-DDX41 抗体

Showing 10 out of 72 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB <b>WB Suggested Anti-DDX41 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
小鼠 非结合性 IF, WB Immunofluorescence of monoclonal antibody to DDX41 on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of DDX41 expression in transfected 293T cell line by DDX41 monoclonal antibody (M01), clone 2F4. Lane 1: DDX41 transfected lysate(70 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
非结合性 WB DDX41 Antibody (N-term) (ABIN1881255) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the DDX41 antibody detected the DDX41 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细
Bat 非结合性 WB 100 μg Log in to see 7至9个工作日
$493.17
详细
非结合性 IP, WB Western Blot and Immunoprecipitation: DDX4 Antibody [ABIN252826] - Detection of Human DDX41 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibody: Affinity purified rabbit anti-DDX41 antibody ABIN252826 used for WB at 1 mcg/ml (A and B) and used for IP at 3 mcg/mg lysate.  Detection: Chemiluminescence with exposure times of 30 seconds (A) and 3 minutes (B). Western Blot: DDX41 Antibody  - Detection of Human and Mouse DDX41 by Western Blot. Samples: Whole cell lysate from HeLa (50, 15 ug) and mouse NIH3T3 (50 ug) cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-DDX41 antibody  used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 7至9个工作日
$486.94
详细
Bat 非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 WB WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1至2个工作日
$358.60
详细
Cow 山羊 非结合性 ELISA, WB ABIN4902607 (0.5µg/ml) staining of Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μL Log in to see 16 Days
$430.08
详细
非结合性 ELISA, WB 100 μg Log in to see 2至3个工作日
$343.75
详细

通过反应活性、应用领域、克隆类型和共轭标记 DDX41 抗体

特性 应用范围 宿主 克隆类型 标记
Human ,
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Mouse (Murine)
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Rat (Rattus)
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引用最多的anti-DDX41 抗体

  1. Human Polyclonal DDX41 Primary Antibody for WB - ABIN1881255 : Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. in Proteomics 2007 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal DDX41 Primary Antibody for IF, ELISA - ABIN565608 : Omura, Oikawa, Nakane, Kato, Ishii, Ishitani, Tokunaga, Nureki: Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. in Scientific reports 2016 (PubMed)

  3. Cow (Bovine) Polyclonal DDX41 Primary Antibody for WB - ABIN2775230 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

更多抗DDX41的相互作用对抗体

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) interaction partners

  1. DDX41 mutations lead to development of high-risk myelodysplastic syndrome.(review)

  2. An increasing number of both inherited and acquired mutations in DDX41 gene are identified from myelodysplastic syndrome and/or acute myeloid leukemia (显示 BCL11A 抗体) (MDS (显示 PAFAH1B1 抗体)/AML (显示 RUNX1 抗体)) patients.

  3. data demonstrate that DDX41 suppresses p21 (显示 CDKN1A 抗体) translation without disturbing the function of p53 (显示 TP53 抗体) to directly induce p21 (显示 CDKN1A 抗体) mRNA expression, this process indirectly requires p53 (显示 TP53 抗体), perhaps in the form of another p53 (显示 TP53 抗体) target gene or as a still undefined posttranscriptional function of p53 (显示 TP53 抗体).

  4. This study uncovered a pathogenic role of p.R525H DDX41 in the slow growth rate of tumor cells. Age-dependent epigenetic alterations or other somatic changes might collaborate with the mutation to cause AML (显示 RUNX1 抗体).

  5. This study expands both the mutation and phenotypic spectra observed in families with germ line DDX41 mutations.

  6. corresponding deletions on 5q35.3 present in 6% of cases led to haploinsufficient DDX41 expression. DDX41 lesions caused altered pre-mRNA splicing and RNA processing

  7. results suggest a mechanism whereby c-di-GMP (显示 NT5C2 抗体) and c-di-AMP (显示 APRT 抗体) are detected by DDX41, which forms a complex with STING to signal to TBK1 (显示 TBK1 抗体)-IRF3 (显示 IRF3 抗体) and activate the interferon (显示 IFNA 抗体) response

  8. DDX41 is an additional DNA sensor that depends on STING to sense pathogenic DNA.

  9. The N-terminal domain of Abs interacts with the phox homology (PX) domain of SNX2 (显示 SNX2 抗体) suggesting that PX domains may also participate in protein-protein interaction.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) interaction partners

  1. Tyr364 and Tyr414 of DDX41 are critical for its recognition of AT-rich DNA and binding to STING, and tandem mass spectrometry identifies Tyr414 as the BTK (显示 BTK 抗体) phosphorylation site.

  2. TRIM21 (显示 TRIM21 抗体) is an interferon (显示 IFNA 抗体)-inducible E3 ligase that induces the Lys48-linked ubiquitination and degradation of DDX41 and negatively regulates the innate immune response to intracellular double-stranded DNA.

  3. DDX41 is an additional DNA sensor that depends on STING to sense pathogenic DNA.

DDX41 抗原简介

蛋白简介

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.

Gene names and symbols associated with DDX41

  • DEAD-box helicase 41 (DDX41) 抗体
  • probable ATP-dependent RNA helicase DDX41 (LOC100215941) 抗体
  • DEAD-box helicase 41 (ddx41) 抗体
  • probable ATP-dependent RNA helicase DDX41 (LOC100638079) 抗体
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (Ddx41) 抗体
  • DEAD-box helicase 41 (Ddx41) 抗体
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (ddx41) 抗体
  • 2900024F02Rik 抗体
  • AA958953 抗体
  • ABS 抗体
  • AI324246 抗体
  • DDX41 抗体
  • wu:fb92e02 抗体
  • zgc:55896 抗体

Protein level used designations for DDX41

DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 , DEAD-box protein abstrakt , probable ATP-dependent RNA helicase DDX41-like , 2900024F02Rik , DEAD box protein 41 , DEAD box protein abstrakt homolog , probable ATP-dependent RNA helicase DDX41 , putative RNA helicase

GENE ID SPECIES
427630 Gallus gallus
462310 Pan troglodytes
700742 Macaca mulatta
100031917 Monodelphis domestica
100058316 Equus caballus
100215941 Hydra magnipapillata
100401323 Callithrix jacchus
100437507 Pongo abelii
100474236 Ailuropoda melanoleuca
100491281 Xenopus (Silurana) tropicalis
100550300 Meleagris gallopavo
100554935 Anolis carolinensis
100638079 Amphimedon queenslandica
51428 Homo sapiens
479274 Canis lupus familiaris
505276 Bos taurus
72935 Mus musculus
314336 Rattus norvegicus
394020 Danio rerio
101102307 Ovis aries
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