Cyclin Y 蛋白 (CCNY)

Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2\; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009].. 再加上,我们可以发Cyclin Y 抗体 (58)Cyclin Y 试剂盒 (18)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
CCNY 219771 Q8ND76
CCNY 67974 Q8BGU5
大鼠 CCNY CCNY 361261  
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
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大肠杆菌(E. Coli) 非结合性   100 μg Log in to see 11至18个工作日
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Baculovirus infected Insect Cells GST tag   50 μg Log in to see 10至12个工作日
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CCNY 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , ,
, ,
Mouse (Murine)

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Fruit Fly (Drosophila melanogaster) Cyclin Y (CCNY) interaction partners

  1. CycY/Eip63E form a cyclin (显示 PCNA 蛋白)/Cdk (显示 CDK4 蛋白) complex that is essential for several developmental processes.

Human Cyclin Y (CCNY) interaction partners

  1. increased expression of CCNY was significantly associated with cell proliferation and migration.

  2. Amplification of gene CCNY is associated with metastatic lung adenocarcinoma.

  3. findings revealed an unrecognized role of Caprin-2 (显示 CAPRIN2 蛋白) in facilitating LRP5 (显示 LRP5 蛋白)/6 constitutive phosphorylation at G2/M through forming a quaternary complex with CDK14 (显示 CDK14 蛋白), Cyclin Y, and LRP5 (显示 LRP5 蛋白)/6.

  4. we believe that CCNY has biological effect in breast cancer (BC) development, and its inhibition via an RNA interference lentiviral system may provide a therapeutic option for BC

  5. CCNY was significantly upregulated in ovarian cancer cell lines and tissues. Significant association was observed between CCNY expression and clinicopathological stage and lymph node metastasis. It significantly exacerbated proliferation, migration, and invasion of A2780 cells, in vitro and in nude mice. It significantly increased c-Myc (显示 MYC 蛋白), cyclin D1 (显示 CCND1 蛋白), PFTK1 (显示 CDK14 蛋白), ki67 (显示 MKI67 蛋白), and OGT (显示 OGT 蛋白) protein expressions in xenograft tumor tissues.

  6. Activation of PCTAIRE-1 (显示 CDK16 蛋白) is mediated through interaction with the phosphorylated form of cyclin Y in complex with 14-3-3 (显示 YWHAQ 蛋白).

  7. Our findings highlight a PFTK1 (显示 CDK14 蛋白)-CCNY complex in activating noncanonical Wnt (显示 WNT2 蛋白) signaling in HCC (显示 FAM126A 蛋白) cells.

  8. Human cyclin Y (CCNY) is a phosphoprotein in vivo and phosphorylation of CCNY by CDK14 (显示 CDK14 蛋白) triggers its ubiquitination and degradation.

  9. Cyclin Y regulates the expression and membrane trafficing of PCTAIRE (显示 CDK16 蛋白) kinases (PCTK). (Review)

  10. CCNY (显示 CDK16 蛋白)binding to CDK16 required a region upstream of the kinase domain and was found to be inhibited by phosphorylation of serine 153, a potential PKA phosphorylation site.

Mouse (Murine) Cyclin Y (CCNY) interaction partners

  1. Here we show that Cyclin Y-like 1 (Ccnyl1) and Cyclin Y (Ccny) have overlapping function and are crucial for mouse embryonic development and mammary stem/progenitor cell functions. Double knockout of Ccnys results in embryonic lethality at E16.5

  2. these results provide a new link between CCNY and lipid metabolism in mice.

  3. CDK16 (显示 CDK16 蛋白) isolated from testis was unphosphorylated, interacted with CCNY, and exhibited kinase activity.

蛋白简介Cyclin Y (CCNY)

蛋白简介

Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2\; MIM 116940) (Li et al., 2009

Gene names and symbols associated with Cyclin Y 蛋白 (CCNY)

  • cyclin Y (CCNY)
  • Cyclin Y (CycY)
  • cyclin Y (Ccny)
  • cyclin Y like 1 (CCNYL1)
  • 1700025H17Rik 蛋白
  • 3110050L10Rik 蛋白
  • 4631402G10Rik 蛋白
  • 5730405I09Rik 蛋白
  • anon-WO0118547.165 蛋白
  • C10orf9 蛋白
  • CBCP1 蛋白
  • CCNX 蛋白
  • CFP1 蛋白
  • CG14939 蛋白
  • Dcyclin Y 蛋白
  • Dmel\\CG14939 蛋白
  • i182 蛋白
  • RGD1565969 蛋白

Protein level used designations for Cyclin Y 蛋白 (CCNY)

cyclin Y , cyclin-Y-like , CG14939-PA , CG14939-PB , CycY-PA , CycY-PB , drosophila cyclin Y , cyc-Y , cyclin box protein 1 , cyclin fold protein 1 , cyclin-X , cyclin-Y , cyclin-box carrying protein 1

GENE ID SPECIES
428412 Gallus gallus
450402 Pan troglodytes
698889 Macaca mulatta
100397648 Callithrix jacchus
34593 Drosophila melanogaster
219771 Homo sapiens
613711 Bos taurus
67974 Mus musculus
361261 Rattus norvegicus
100861154 Capra hircus
101122455 Ovis aries
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