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C4orf7 encodes a small secreted protein that is expressed in follicular dendritic cells. 再加上，我们可以发Chromosome 4 Open Reading Frame 7 蛋白 (3) 和 和数多这个蛋白质的别的产品。
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Human Polyclonal C4orf7 Primary Antibody for IHC (p) - ABIN5578032
Nakayama, Kobayashi, Matsui, Matsumura, Iwai, Noda, Yamazaki, Kurita-Ochiai, Yoshimura, Shinomura, Ganss, Ogata: Localization and expression pattern of amelotin, odontogenic ameloblast-associated protein and follicular dendritic cell-secreted protein in the junctional epithelium of inflamed gingiva. in Odontology 2016
Human Polyclonal C4orf7 Primary Antibody for IHC, IHC (p) - ABIN4311299
Dabija-Wolter, Bakken, Cimpan, Johannessen, Costea: In vitro reconstruction of human junctional and sulcular epithelium. in Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2013
Our results demonstrate a novel biological activity of FDC-SP in controlling B-cell IgA production and identify FDC-SP-deficient mice as a novel mouse model of IgAN.
These studies show that TNF-alpha stimulates human FDC-SP gene transcription by targeting YY1, GATA, C/EBP2 and C/EBP3 in the FDC-SP gene promoter.
LPS-induced upregulation of FDC-SP expression in human periodontal ligament cells may enhance osteoclastogenesis in periodontal disease.
FDC-SP may be involved in IgA production in the tonsils of Immunoglobulin A nephropathy patients.
FDC-SP overexpression inhibits osteogenic differentiation of hPDLCs. study contributes to a better understanding of biological functions governing FDC-SP-induced hPDLC differentiation.
Our findings demonstrate that transfection with FDC-SP has negligible adverse effect on proliferation of hPDLCs and imply the biological function of FDC-SP as a fibroblastic phenotype stabilizer
The role of C4orf7 in ovarian cancer cell morphology, motility and invasion was demonstrated.
FDC-SP has a very restricted tissue distribution, expressed by activated FDCs from tonsils and TNF-alpha-activated FDC-like cell lines, but not by B cell lines, primary germinal center B cells, or anti-CD40 plus IL-4-activated B cells.
Since only normal tissue was examined, these findings suggest that FDC-SP plays an important but previously unsuspected role within oral connective tissue.
These results provide the first evidence for immunomodulatory activities of FDC-SP and implicate this molecule as a regulator of B cell responses.
This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion.
follicular dendritic cell secreted peptide
, chromosome 4 open reading frame 7
, FDC secreted protein