Chemokine-Like Receptor 1 (CMKLR1) ELISA试剂盒

may be a member of the chemokine receptor family [RGD, Feb 2006].. 再加上,我们可以发CMKLR1 抗体 (157)CMKLR1 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
CMKLR1 1240 Q99788
CMKLR1 14747 P97468
CMKLR1 60669  
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Human Chemokine-Like Receptor 1 (CMKLR1) interaction partners

  1. levels in cord blood, peripheral blood, adipose tissue and placenta tissue significantly higher in gestational diabetes

  2. CMKLR1 and GPR1 were widely expressed in vascular smooth muscle.

  3. Both ALX and ChemR23 were present in human synovium and medial tibial plateau bone obtained following total knee replacement surgery for osteoarthritis.

  4. Results show that ChemR23 is highly expressed in squamous oesophageal cancer tumors and cell lines.

  5. CMKLR1 exacerbated the proliferation and migration of VSMCs by activating ERK1/2.

  6. We demonstrated that chemerin is linked to metabolic syndrome components. Moreover, serum chemerin levels were associated significantly with obesity, especially visceral adipose tissue, in subjects with T2DM [type 2 diabetes mellitus].

  7. Study shows that hepatic CMKLR1 mRNA is weakly associated with features of NASH in male patients only.

  8. Our results show that higher levels of circulating chemerin, CRP, fibrinogen, and ESR are associated with an increased risk of developing colorectal cancer

  9. Data show inverse Relationship of the CMKLR1 Relative Expression and Chemerin Serum Levels in Obesity with Dysmetabolic Phenotype and Insulin Resistance

  10. Results indicate that Abeta42 activates CMKLR1, leading to glia cell migration and clearance of Abeta42; and is involved in Abeta processing and clearance

  11. Gestational obesity and gestational diabetes mellitus may contribute to elevated serum chemerin. Serum chemerin in pregnancy was associated with insulin resistance and triglycerides. Chemerin gene may play a role both in obese and gestational diabetes mellitus patients

  12. Increased chemerin expression in dermal blood vessels may be associated with the development of digital ulcers in systemic sclerosis.

  13. The study for the first time confirmed a marked expression of chemerin and CMKLR1 in the liver of chronic hepatitis patients.

  14. ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.

  15. The effects of diclofenac on the incidence of pancreatitis following endoscopic retrograde cholangiopancreatography via lipoxin A4 and resolvin D1 and E1 levels is reported.

  16. Results lend some support to a presumable role of locally produced chemerin in the progression of atherosclerotic lesions, possibly acting through its CMKLR1 receptor.

  17. This study identified the up-regulation of ChemR23 in post-traumatic injury of calcaneal articular fracture

  18. ChemR23 is expressed in neutrophil granules and rapidly upregulated upon neutrophil activation.

  19. Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain.

  20. Chemerin receptor showed increased expression in the lymph nodes and the spleen.

Mouse (Murine) Chemokine-Like Receptor 1 (CMKLR1) interaction partners

  1. PI3K inhibition attenuates hepatic steatosis and KC-mediated inflammation via down-regulation of CMKLR1 and NLRP3 in HFD mice

  2. These findings support a fundamental biological function for chemerin/CMKLR1 to balance osteoblastogenic and adipogenic signaling and thereby contribute to the maintenance of pluripotency in mesenchymal stem cells.

  3. Chemerin-CMKLR1 activates Akt/mTOR and ERK pathways and facilitates preadipocyte proliferation, adipogenesis, and angiogenesis. Gax weakens the effect of chemerin on preadipocyte biofunctions.

  4. CMKLR1 exacerbated the proliferation and migration of VSMCs by activating ERK1/2.

  5. CMKLR1 gene deletion attenuates the effects of chronic DHT treatment on ovarian function in experimental PCOS, likely via BMP4 signaling.

  6. Loss of CMKLR1 exacerbates glucose intolerance and insulin resistance in mice fed high fat diets.

  7. The chemerin15 (C15) precursor, chemerin, and its receptor, ChemR23, are both upregulated after skin damage and the receptor is expressed by macrophages, neutrophils, and keratinocytes. C15 delivery dampens immediate inflammatory events.

  8. Results indicate that Abeta42 activates CMKLR1, leading to glia cell migration and clearance of Abeta42; and is involved in Abeta processing and clearance

  9. Increased chemerin expression in dermal blood vessels may be associated with the development of digital ulcers in systemic sclerosis.

  10. In brown adipose tissue, cold acclimation strongly diminished chemerin gene expression, whereas obesogenic diets augmented expression.

  11. Hematopoietic Deletion of Cmklr1 Does not Affect the Development of Insulin Resistance or nonalcoholic fatty liver disease.

  12. ChemR23 is expressed in neutrophil granules and rapidly upregulated upon neutrophil activation.

  13. Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain.

  14. Data suggest that chemerin/ChemR23 signaling is not essential for adipocyte differentiation, but it appears to play a role in control of body weight and energy metabolism as overweight/obesity progresses.

  15. ChemR23 forms homomers, and provide data suggesting that ChemR23 also forms heteromers witChemR23 forms homomers, and provide data suggesting that ChemR23 also forms heteromers with the chemokine receptors CCR7 and CXCR4.

  16. Downstream targets of Chemerin/ChemR23 signaling are phosphorylated in vitro and are expressed in mouse tooth development, suggesting roles for Chemerin/ChemR23-mediated epithelial-mesenchymal cell signaling during tooth morphogenesis.

  17. These results rule out the direct anti-inflammatory effect of chemerin on macrophages ex vivo, described previously in the literature, despite the expression of a functional ChemR23 receptor in these cells.

  18. ChemR23-dependent recruitment of plasmacytoid dendritic cells contributes to adaptive immune responses and viral clearance, and also enhances the inflammatory response;the chemerin/ChemR23 system plays important roles in the physiopathology of viral pneumonia

  19. the results of this study reveal a novel involvement for CMKLR1 in myogenic differentiation in vitro and suggest an important role for CMKLR1 in proper muscle development in vivo.

  20. Collectively these data provide compelling evidence that CMKLR1 influences adipose tissue development, inflammation, and glucose homeostasis and may contribute to the metabolic derangement characteristic of obesity and obesity-related diseases.

CMKLR1 抗原简介

Antigen Summary

may be a member of the chemokine receptor family

Gene names and symbols associated with CMKLR1

  • chemerin chemokine-like receptor 1 (CMKLR1) 抗体
  • chemokine-like receptor 1 (Cmklr1) 抗体
  • chemerin chemokine-like receptor 1 (Cmklr1) 抗体
  • chemokine-like receptor 1 (cmklr1) 抗体
  • chemerin chemokine-like receptor 1 (cmklr1) 抗体
  • CHEMERINR 抗体
  • ChemR23 抗体
  • Cmklr-1 抗体
  • CMLKR1 抗体
  • DEZ 抗体
  • GPCR 抗体
  • Gpcr27 抗体
  • mcmklr1 抗体
  • RVER1 抗体
  • si:ch211-240b21.3 抗体

Protein level used designations for CMKLR1

G-protein coupled receptor ChemR23 , G-protein coupled receptor DEZ , chemerin receptor , chemokine receptor-like 1 , orphan G-protein coupled receptor, Dez , resolvin E1 receptor , G-protein coupled receptor 27 , G-protein coupled chemoattractant-like receptor , chemokine-like receptor 1 , seven transmembrane helix receptor

GENE ID SPECIES
1240 Homo sapiens
14747 Mus musculus
60669 Rattus norvegicus
486321 Canis lupus familiaris
557341 Danio rerio
615411 Bos taurus
100216025 Xenopus (Silurana) tropicalis
780421 Sus scrofa
100583846 Nomascus leucogenys
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