蛋白简介

Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

Gene names and symbols associated with anti-Cathepsin F (CTSF) 抗体

• cathepsin F (CTSF) 抗体
• cathepsin F (ctsf) 抗体
• cathepsin F (Ctsf) 抗体
• cathepsin W (ctsw) 抗体
• cathepsin F (Tsp_02382) 抗体

• ACYPI000376 抗体
• AI481912 抗体
• catf 抗体
• CATSF 抗体
• cb420 抗体
• 显示所有的同义词和别名
• CLN13 抗体
• Ctsf 抗体
• LOC100101596 抗体
• MGC140519 抗体
• sb:cb420 抗体
• zgc:153093 抗体

Protein level used designations for anti-Cathepsin F (CTSF) 抗体

cathepsin F , hypothetical protein LOC100158959 , Cathepsin F , cathepsin F-like