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Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). 再加上，我们可以发CNPY2 抗体 (53) 和 CNPY2 蛋白 (9)和数多这个蛋白质的别的产品。
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Human CNPY2 ELISA Kit for Sandwich ELISA - ABIN1169616
Yan, Gong, Zhai, Feng, Wu, He, Guo, Wang, Guo, Xie, Li: Decreasing CNPY2 Expression Diminishes Colorectal Tumor Growth and Development through Activation of p53 Pathway. in The American journal of pathology 2016
Free CNPY2 then engages protein kinase (显示 CDK7 ELISA试剂盒) R-like endoplasmic reticulum kinase (PERK (显示 EIF2AK3 ELISA试剂盒)) to induce expression of the transcription factor C/EBP homologous protein (CHOP (显示 DDIT3 ELISA试剂盒)), thereby initiating the unfolded protein response.
CNPY2 may play a critical role in colorectal cancer development by enhancing cell proliferation, migration, and angiogenesis and by inhibiting apoptosis through negative regulation of the p53 (显示 TP53 ELISA试剂盒) pathway
The data demonstrate CNPY2 is widely distributed in tissues and suggest the protein has biological functions that have yet to be identified.
CNPY2 is a HIF-1alpha (显示 HIF1A ELISA试剂盒)-regulated, secreted angiogenic growth factor that promotes smooth muscle cell migration, proliferation, and tissue revascularization.
Overexpression of CNPY2 can activate the AKT (显示 AKT1 ELISA试剂盒)/GSK3beta pathway, which leads to the inactivation of GSK-3beta. The inactivation of GSK-3beta increases the level of Snail (显示 SNAI1 ELISA试剂盒), and then decreases the expression of E-cadherin (显示 CDH1 ELISA试剂盒) to promote EMT (显示 ITK ELISA试剂盒).
CNPY2 can serve as a therapeutic target to promote the effect of chemotherapy in non-small cell lung cancer.
CNPY2 isoform2 represents as a novel and valuable prognostic indicator for colorectal cancer patients.
These findings suggested that CNPY2 promoted cancer cell growth in renal cell carcinoma (显示 MOK ELISA试剂盒) cells through regulating TP53 (显示 TP53 ELISA试剂盒) gene expression.
Our results are consistent with an important role of FGF21 (显示 FGF21 ELISA试剂盒) and Cnpy2/Msap in the regulation of LDLRs in cultured cells.
MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain in fetal and adult brain.
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (By similarity).
MIR-interacting saposin-like protein
, protein canopy homolog 2
, putative secreted protein ZSIG9
, transmembrane protein 4
, canopy 2 homolog
, putative secreted protein Zsig9