anti-C-Type Lectin Domain Family 4, Member E (CLEC4E) 抗体

CLEC4E encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. 再加上,我们可以发CLEC4E 试剂盒 (23)CLEC4E 蛋白 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CLEC4E 26253 Q9ULY5
CLEC4E 56619 Q9R0Q8
CLEC4E 450223 Q67EQ1
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antibodies-online.cn销售最多的anti-CLEC4E 抗体

Showing 10 out of 68 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 ELISA, ICC, IF, IHC, IHC (p), WB Western Blot: CLEC4E Antibody (16E3) [NBP1-49311] - Cell lysates of HeLa (35ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CLEC4E (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Immunohistochemistry-Paraffin: CLEC4E Antibody (16E3) [NBP1-49311] - Paraffin embedded sections of colorectal cancer tissue were incubated with anti-human MINCLE antibody (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB). 0.1 mL Log in to see 12至15个工作日
$415.44
详细
小鼠 非结合性 FACS, IHC, IHC (p), WB 100 μL Log in to see 7至9个工作日
$522.50
详细
小鼠 非结合性 EIA, IF, IHC (p), WB 0.1 mL Log in to see 6至8个工作日
$412.50
详细
小鼠 Alexa Fluor 488 ELISA, ICC, IF, IHC, IHC (p), WB Flow Cytometry: CLEC4E Antibody (16E3)   - An intracellular stain was performed on U-937 cells with CLEC4E Antibody (16E3) NBP1-49311AF488 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 488. Flow Cytometry: CLEC4E Antibody (16E3)   - An intracellular stain was performed on U87MG cells with CLEC4E Antibody (16E3)  (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 488. 0.1 mL Log in to see 14至17个工作日
$514.63
详细
小鼠 Alexa Fluor 647 ELISA, ICC, IF, IHC, IHC (p), WB Flow Cytometry: CLEC4E Antibody (16E3)   - An intracellular stain was performed on U87MG cells with CLEC4E Antibody (16E3)  (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 647 0.1 mL Log in to see 14至17个工作日
$514.63
详细
小鼠 非结合性 WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (49.83 KDa) . Dilution: 1:500~1000 CLEC4E monoclonal antibody (M08), clone 2D12. Western Blot analysis of CLEC4E expression in K-562. Dilution: 1:500~1000 100 μg Log in to see 8至11个工作日
$461.00
详细
小鼠 非结合性 ELISA, WB CLEC4E monoclonal antibody (M08), clone 2D12. Western Blot analysis of CLEC4E expression in K-562. Western Blot detection against Immunogen (49.83 KDa) . 100 μg Log in to see 11至12个工作日
$440.00
详细
非结合性 WB Western blot testing of human samples with CLEC4E antibody at 2ug/ml. 100 μg Log in to see 2至3个工作日
$302.50
详细
小鼠 非结合性 ELISA, IF, IHC (p), WB Immunofluorescence of human HeLa cells stained with monoclonal CLEC4E monoclonal antibody, clone AT16E3  (1 : 500) with Texas Red (Red). Nucleus was stained by Hoechst 33342 (Blue). Cell lysates of HeLa (35 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with CLEC4E monoclonal antibody, clone AT16E3  (1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 100 μL Log in to see 11至12个工作日
$355.73
详细
小鼠 非结合性 IF, ELISA, WB   50 μL Log in to see 7至9个工作日
$639.83
详细

引用最多的anti-CLEC4E 抗体

  1. Human Monoclonal CLEC4E Primary Antibody for ELISA, WB - ABIN565251 : Bugarcic, Hitchens, Beckhouse, Wells, Ashman, Blanchard: Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans. in Glycobiology 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CLEC4E Primary Antibody for IF (p), IHC (p) - ABIN1385725 : He, Xu, Li, Guo, Hu, Guo, Tang, Chen, Zhang, Tang, Zhang: Macrophage-Inducible C-Type Lectin/Spleen Tyrosine Kinase Signaling Pathway Contributes to Neuroinflammation After Subarachnoid Hemorrhage in Rats. in Stroke 2015 (PubMed)

  3. Human Monoclonal CLEC4E Primary Antibody for ELISA, ICC - ABIN4299166 : de Rivero Vaccari, Brand, Berti, Alonso, Bullock, de Rivero Vaccari: Mincle signaling in the innate immune response after traumatic brain injury. in Journal of neurotrauma 2015 (PubMed)

更多抗CLEC4E的相互作用对抗体

Human C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. Mincle has the ability to survey mycolate-derived glycolipids from actinomycetes, distinguishing non-pathogenic (e.g. Rhodococcus spp.) and pathogenic (e.g. Mycobacterium tuberculosis) species on the basis of alpha-chain (显示 FCGRT 抗体) length.

  2. combination adjuvant systems demonstrate markedly different immune activation with age, with combined DC activation via Macrophage-inducible C-type lectin and TLR7 (显示 TLR7 抗体)/8 representing a novel approach to enhance the efficacy of early-life vaccines.

  3. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar lavage fluids of mice and patients with pneumococcal pneumonia

  4. a nonredundant role for Clec4e in coordinating major biological pathways involved in atherosclerosis

  5. CLEC4E expression is significantly upregulated in human masticatory mucosa during wound healing

  6. The expression of Mincle increases significantly during the early period of Aspergillus fumigatus infection, while expression of eight corresponding cytokines changes. Mincle, as a pattern recognition receptor, may play a role in the early innate immune response of the corneal resistance against fungus.

  7. Induction of Mincle by Helicobacter pylori and consequent anti-inflammatory signaling denote a bacterial survival strategy.

  8. our findings identify mincle as a contributor to the inflammatory response after traumatic brain injury

  9. Data indicate that MINCLE receptor is able to mediate the response to trehalose-6,6-dimycolate (TDM) dependent on SYK (显示 SYK 抗体) kinase and CARD9 (显示 CARD9 抗体) protein.

  10. mincle is a fungal receptor that can suppress antifungal immunity and, as such, is a potential therapeutic target.

Mouse (Murine) C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. Mincle activation by cholesterol sulfate causes the secretion of a range of proinflammatory mediators in response to skin damage.

  2. this study shows that mincle inhibits neutrophils and macrophages apoptosis in Aspergillus fumigatus keratitis

  3. Mincle is induced specifically on M1 macrophages, where Mincle-Syk (显示 SYK 抗体) signaling promotes and maintains inflammatory phenotypes of M1 macrophages in acute renal inflammation.

  4. work implicates a novel innate immune driver of Con (显示 KITLG 抗体) A hepatitis and, more broadly, suggests a potential role for Mincle in diseases governed by sterile inflammation.

  5. Mincle deletion results in TLR4 (显示 TLR4 抗体)-mediated inflammation.

  6. Priming by Mincle-deficient dendritic cells (DCs).

  7. Thus, macrophage activation by the corynebacterial cell wall relies on TLR2-driven robust Mincle expression and the cooperative action of both receptors.

  8. this study shows that immune activation in vitro and in vivo by trehalose esters of simple fatty acids requires two acyl chains of length and involves Mincle

  9. Attenuated neutrophil extracellular trap formation in Mincle-/- neutrophils correlates with impaired autophagy activation in vitro and in vivo, whereas reactive oxygen species formation in these neutrophils remained intact.

  10. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar lavage fluids of mice and patients with pneumococcal pneumonia

Cow (Bovine) C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. The structure of an extended portion of the extracellular domain of mincle, beyond the minimal C-type carbohydrate recognition domain, also constrains the way the binding domains may interact on the surface of macrophages.

  2. The data demonstrate how mincle bridges between the surfaces of the macrophage and the mycobacterium.

Guinea Pig C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. the function of the guinea pig homologue of Mincle (gpMincle) and MCL (显示 CLEC4D 抗体) (gpMCL). gpMincle directly bound to trehalose-6,6'-dimycolate

CLEC4E 抗原简介

蛋白简介

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Gene names and symbols associated with CLEC4E

  • C-type lectin domain family 4 member E (CLEC4E) 抗体
  • C-type lectin domain family 4, member e (Clec4e) 抗体
  • C-type lectin domain family 4, member E (Clec4e) 抗体
  • C-type lectin domain family 4 member E (LOC611538) 抗体
  • C-type lectin domain family 4 member E (Clec4e) 抗体
  • C86253 抗体
  • CLEC4E 抗体
  • Clecsf9 抗体
  • Mincle 抗体

Protein level used designations for CLEC4E

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9 , C-type lectin domain family 4 member E , C-type lectin superfamily member 9 , macrophage-inducible C-type lectin , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 9 , C-type lectin, superfamily member 9 , immunoreceptor , C-type lectin domain family 4, member E

GENE ID SPECIES
26253 Homo sapiens
56619 Mus musculus
450223 Rattus norvegicus
514797 Bos taurus
611538 Canis lupus familiaris
722250 Macaca mulatta
735637 Pan troglodytes
100135686 Ovis aries
100350649 Oryctolagus cuniculus
100726838 Cavia porcellus
102121864 Macaca fascicularis
110260748 Sus scrofa
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