CLEC4E 抗体 (AA 51-150) (AbBy Fluor® 647)
Quick Overview for CLEC4E 抗体 (AA 51-150) (AbBy Fluor® 647) (ABIN1399620)
抗原
See all CLEC4E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Cow,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CLECSF9/CLEC4E
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亚型
- IgG
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
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别名
- CLEC 4E
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背景
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Synonyms: C type lectin domain family 4 member E, C type lectin superfamily member 9, C-type calcium dependent carbohydrate recognition domain lectin superfamily member 9, C-type lectin domain family 4 member E, C-type lectin superfamily member 9, CLC4E_HUMAN, CLEC 4E, CLEC4E Clec4e, CLECSF9, Macrophage inducible C type lectin, Macrophage-inducible C-type lectin, MINCLE.
Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
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基因ID
- 26253
抗原
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