Bromodomain Containing 1 蛋白 (BRD1)

BRD1 encodes a protein of unknown function.

列出全部蛋白 基因 基因ID UniProt
 BRD1 BRD1 23774 O95696
小鼠 BRD1 BRD1 223770  
大鼠 BRD1 BRD1 315210  
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
大肠杆菌(E. Coli) His tag 100 μg Log in to see 2至3个工作日
大肠杆菌(E. Coli) His tag   100 μg Log in to see 2至3个工作日
大肠杆菌(E. Coli) His tag,DYKDDDDK Tag Recombinant BRD1 (556-688) activity using AlphaScreen. BRD1 (556-688) titration was assessed using an AlphaScreen® assay. Titration curves were generated to show signal response in the presence of modified peptide substrate at increasing protein concentrations. This data was generated and kindly provided courtesy of ChemPartner. Recombinant BRD1 (556-688) protein gel. BRD1 (556-688) protein was run on an SDS-PAGE gel and stained with Coomassie blue. 100 μg Log in to see 1至2个工作日
大肠杆菌(E. Coli) GST tag,His tag 100 μg Log in to see 15至18个工作日

更多Bromodomain Containing 1 (BRD1)互动伙伴

Human Bromodomain Containing 1 (BRD1) interaction partners

  1. TIMP-4 (显示 TIMP4 蛋白), NT-proANP, NT-proBNP were strongest associated with PAF (显示 PAF 蛋白) and AHRE (显示 AHR 蛋白). The discriminatory performance of CHADS2-VASc for PAF (显示 PAF 蛋白) was increased by addition of selected biomarkers.

  2. Structural and mechanistic insights into regulation of HBO1 (显示 MYST2 蛋白) histone acetyltransferase activity by BRPF2 have been presented.

  3. Reduced BRD1 expression is associated with Schizophrenia.

  4. Findings show that BRD1 primarily binds in close proximity to transcription start sites and regulates expression of numerous genes, many of which are involved with brain development and susceptibility to mental disorders.

  5. The PHD (显示 PDC 蛋白) finger of BRPF2 can potentially bind DNA non-specifically with an evolutionarily conserved and positively charged surface.

  6. Recognition of unmodified histone H3 (显示 HIST3H3 蛋白) by the first PHD (显示 PDC 蛋白) finger of bromodomain-PHD finger protein 2 (显示 PHF2 蛋白) provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF (显示 KAT6B 蛋白)).

  7. BRD1 may have a role in schizophrenia and bipolar affective disorder

  8. The association of BRD1 with schizophrenia in a Japanese population, was analysed.

  9. These results suggest a general role of BRD1 in the cell and stress that the two BRD1 variants may play different roles in the etiology of psychiatric disease.

Mouse (Murine) Bromodomain Containing 1 (BRD1) interaction partners

  1. Brd1(+/-) mice exhibit relational encoding deficits, compromised working and long term memory, as well as impaired executive cognitive functioning with cognitive behaviors relying on medial prefrontal cortex being particularly affected. Akin to patients with schizophrenia, the cognitive deficits displayed by Brd1(+/)(-) mice are not global, but selective.

  2. results demonstrate widespread gene expression alterations in the brains of Brd1 +/- mice.

  3. BRPF2-MOZ complexes play an important role in the differentiation of embryonic stem cells via H3K14 acetylation.

  4. Brd1-mediated Hbo1 (显示 MYST2 蛋白) activity is crucial for efficient activation of CD8 (显示 CD8A 蛋白) expression via acetylation at H3K14, which serves as an epigenetic mark that promotes the recruitment of transcription machinery to the CD8 (显示 CD8A 蛋白) enhancers.

  5. The Hbo1 (显示 MYST2 蛋白)-Brd1 complex is the major H3K14 HAT required for transcriptional activation of erythroid developmental regulator (显示 GIPC1 蛋白) genes.

蛋白简介Bromodomain Containing 1 (BRD1)


This gene encodes a protein of unknown function. The protein contains a bromodomain, a sequence motif often found in transcriptional coactivators, and localizes to the nucleus in testis and several other cell types.

Gene names and symbols associated with Bromodomain Containing 1 蛋白 (BRD1)

  • bromodomain containing 1 (BRD1)
  • bromodomain containing 1 L homeolog (brd1.L)
  • bromodomain containing 1a (brd1a)
  • bromodomain containing 1 (brd1)
  • bromodomain containing 1 (Brd1)
  • 1110059H06Rik 蛋白
  • AI316859 蛋白
  • BDNF 蛋白
  • brd1 蛋白
  • BRL 蛋白
  • BRPF1 蛋白
  • BRPF2 蛋白
  • im:7138929 蛋白
  • LOC733743 蛋白
  • MGC80898 蛋白
  • MGC146307 蛋白
  • mKIAA4191 蛋白
  • si:dkey-164m14.6 蛋白

Protein level used designations for Bromodomain Containing 1 蛋白 (BRD1)

bromodomain-containing protein 1 , bromodomain containing 1 , bromodomain containing protein 1 , bromodomain-containing protein 1-like , BR140-like protein , bromodomain and PHD finger-containing protein 2

100050039 Equus caballus
444273 Xenopus laevis
470245 Pan troglodytes
569574 Danio rerio
733743 Xenopus (Silurana) tropicalis
100477457 Ailuropoda melanoleuca
100586701 Nomascus leucogenys
23774 Homo sapiens
417731 Gallus gallus
481198 Canis lupus familiaris
100336626 Bos taurus
223770 Mus musculus
315210 Rattus norvegicus