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In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies.
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Rare missense variants within a single gene, abca13, form yin yang haplotypes.
CIAPIN1 (显示 CIAPIN1 抗体) and ABCA13 may be novel markers of poor outcome in pre-chemotherapy serous carcinoma effusions.
The results of this study demonstrated that common genetic variants at ABCA13 are unlikely to be related to the pathogenesis of schizophrenia in the Han Chinese population.
No copy number variation including ABCA13 was identified in schizophrenia, bipolar disorder, or major depressive disorder samples, nor in the controls.
An alternative human ABCA13 transcript and protein.
ABCA13 is a candidate gene in schizophrenia, bipolar disorder, and depression
T4031A replacement affects the function of ABCA13 in the brain
In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.
ATP binding cassette transporter A13
, ATP-binding cassette sub-family A member 13
, ATP-binding cassette transporter
, ATP-binding cassette, sub-family A (ABC1), member 13
, ATP binding cassette, sub-family A (ABC1), member 13
, ATP-binding cassette sub-family A member 13-like