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Human Polyclonal RIMS3 Primary Antibody for IHC, ELISA - ABIN1003092
Wang, Sugita, Sudhof: The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins. in The Journal of biological chemistry 2000
Show all 2 Pubmed References
mouse RIM3 proteins carrying amino acid substitutions that correspond to mutations associated with autism (E176A and M259V) modify RIM3 interaction with VDCC beta-subunits
The Gsdma3 may play a role in the proliferation and differentiation of epidermal cells and hair follicles through negatively regulating beta-catenin (显示 CTNNB1 抗体) expression.
in mouse skin keratinocytes, Gsdma3 expression could be regulated by TNF-alpha (显示 TNF 抗体).
Gsdma3 gene mutation interfered with catagen formation during mouse hair follicle cycle and, by upregulation of Caspase-3 (显示 CASP3 抗体) expression and promotion of apoptosis, Gsdma3 gene could play an essential role in normal catagen induction.
These results suggest that Gsdma3 is necessary in hair shaft differentiation, and involved in Msx2 regulatory pathway.
Gsdm3 reflects a mutation hotspot and that Gsdm3 mutations cause alopecia in Rco2, Re(den), and Bsk (显示 EPHA5 抗体) mice.
We identified four novel CNVs in three different genes (one duplication in USH2A (显示 USH2A 抗体) gene, two duplications in CEP290 (显示 CEP290 抗体) gene, and one duplication in RIMS2 (显示 RIMS2 抗体) gene) in total four families, at a detection rate of 8% (4/50).
Western blot analysis shows increased piccolo (显示 PCLO 抗体) protein expression in the amygdala in schizophrenia.
Plays a role in the transition from catagen to telogen at the end of hair follicle morphogenesis.
regulating synaptic membrane exocytosis 3
, bare skin
, gasdermin 3
, recombination induced mutation 3
, regulating synaptic membrane exocytosis protein 3
, RIM 3
, RIM3 gamma
, Rab-3 interacting molecule 3
, rab-3-interacting molecule 3