RIMS3 抗体 (N-Term)
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Quick Overview for RIMS3 抗体 (N-Term) (ABIN500610)
抗原
See all RIMS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Rim3 at N-term. It is predicted to have no cross-reactivity to other Rim proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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纯化方法
- Peptide affinity chromatography
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免疫原
- Rim3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human Rim3.
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亚型
- IgG
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anti-Regulating Synaptic Membrane Exocytosis 3 (RIMS3) (C-Term) antibody
RIMS3 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 3 (RIMS3) (C-Term) antibodyRIMS3 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 3 (RIMS3) antibodyRIMS3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))
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别名
- RIMS3
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背景
- Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.Synonyms: KIAA0237, Nim3, RIM 3, RIM3 gamma, Rab-3-interacting molecule 3, Regulating synaptic membrane exocytosis protein 3
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基因ID
- 9783
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NCBI登录号
- NP_055562
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UniProt
- Q9UJD0
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途径
- Stem Cell Maintenance, Synaptic Vesicle Exocytosis
抗原
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