anti-ANGPTL4 (ANGPTL4) 抗体产品概述

Full name:
anti-Angiopoietin-Like 4 抗体 (ANGPTL4)
在www.antibodies-online.cn可供154 Angiopoietin-Like 4 (ANGPTL4) 抗体的25不同的供货商。 再加上,我们可以发ANGPTL4 试剂盒 (60)ANGPTL4 蛋白 (42)和数多这个蛋白质的别的产品。 总共270 ANGPTL4产品已列进来了。
别名:
ANGPTL2, ANGPTL4, ARP4, Bk89, fiaf, HFARP, im:7144703, Ng27, NL2, PGAR, Pgarg, pp1158, si:rp71-39b20.7

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  1. Human Monoclonal ANGPTL4 Primary Antibody for ELISA - ABIN395110 : Ma, Jham, Hu, Friedman, Basile, Molinolo, Sodhi, Montaner: Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 5 references for 395110

  2. Human Polyclonal ANGPTL4 Primary Antibody for EIA, IHC (p) - ABIN950414 : Maxwell, Bendall, Staples, Jarvis, Crandall: Phylogenetics applied to genotype/phenotype association and selection analyses with sequence data from angptl4 in humans. in International journal of molecular sciences 2010 (PubMed)
    Show all 3 references for 950414

  3. Human Polyclonal ANGPTL4 Primary Antibody for ELISA, WB - ABIN1169313 : Broxmeyer, Srour, Cooper, Wallace, Hangoc, Youn: Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors. in Blood cells, molecules & diseases 2012 (PubMed)

  4. Human Polyclonal ANGPTL4 Primary Antibody for WB - ABIN526478 : Makoveichuk, Sukonina, Kroupa, Thulin, Ehrenborg, Olivecrona, Olivecrona: Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed. in Biochemical and biophysical research communications 2012 (PubMed)

  5. Human Polyclonal ANGPTL4 Primary Antibody for ELISA, WB - ABIN565533 : Yokouchi, Eto, Nishimura, Takeda, Kaburagi, Yamamoto, Yasuda: Angiopoietin-like protein 4 (ANGPTL4) is induced by high glucose in retinal pigment epithelial cells and exhibits potent angiogenic activity on retinal endothelial cells. in Acta ophthalmologica 2013 (PubMed)

  6. Human Polyclonal ANGPTL4 Primary Antibody for FACS, IHC (p) - ABIN653155 : Wan, Wen, Dong, Tang, Liu, Liu, Tao, Gao, Sun, Cao, Fan, Wu: Establishment of monoclonal HCC cell lines with organ site-specific tropisms. in BMC cancer 2015 (PubMed)

更多抗ANGPTL4的相互作用对抗体

Cow (Bovine) Angiopoietin-Like 4 (ANGPTL4) interaction partners

  1. increase in angiopoietin-like protein 4 messenger RNA across multiple models of altered energy balance identifies it as an adipokine that is uniquely responsive to changes in energy balance in the lactating dairy cow

  2. These findings indicate that liver and adipose tissue are key sources of ANGPTL4 in cattle; the protein was also highly abundant in ruminal epithelium, making it possible that commensal microbes may influence ANGPTL4 synthesis and secretion.

Mouse (Murine) Angiopoietin-Like 4 (ANGPTL4) interaction partners

  1. physiological changes in adipose tissue ANGPTL4 expression during fasting and cold resulted in inverse changes in the amount of mature-glycosylated LPL (显示 LPL 抗体) in wild-type mice, but not Angptl4(-/-) mice. We conclude that ANGPTL4 promotes loss of intracellular LPL (显示 LPL 抗体) by stimulating LPL (显示 LPL 抗体) degradation after LPL (显示 LPL 抗体) processing in the endoplasmic reticulum (ER).

  2. This study shows that TNF-alpha (显示 TNF 抗体), by a Foxo1 (显示 FOXO1 抗体) dependent pathway, increases the transcription of ANGPTL4 which is secreted by the cells and causes inactivation of LPL (显示 LPL 抗体).

  3. Angptl4-deficient mice show impaired insulin (显示 INS 抗体) secretion and dysmorphic pancreatic islets.

  4. Angptl4 induces obesity-associated metabolic disorders. The present study suggested that Angptl4 promotes liver steatosis and lipolysis, in addition to impairing liver function; while Angptl4 improves glucose tolerance and insulin (显示 INS 抗体) resistance, in addition to causing the downregulation of various insulin (显示 INS 抗体) signaling pathway-associated genes.

  5. ANGPTL4 is part of a shuttling mechanism that directs fatty acids derived from circulating triglyceride-rich lipoproteins to brown adipose tissue during cold.

  6. This model suggests a general mechanism by which TAG trafficking is coordinated by lipasin, Angptl3 (显示 ANGPTL3 抗体) and Angptl4 at different nutritional statuses.

  7. These results reveal that FTO (显示 FTO 抗体) regulates fatty acid mobilization in adipocytes and thus body weight in part through posttranscriptional regulation of Angptl4.

  8. these results suggest that IL-1beta (显示 IL1B 抗体) increases Angptl4 expression through a mechanism dependent on the JNK (显示 MAPK8 抗体)-MAPK (显示 MAPK1 抗体) signaling pathway in MC3T3-E1 cells.

  9. glucagon receptor (显示 GCGR 抗体) antagonist improves glycemia in diet-induced obese angptl4 knockout mice without increasing glucagon (显示 GCG 抗体) levels or alpha-cell proliferation, underscoring the importance of this protein.

  10. Angptl4 may play a role in osteoblastic differentiation, and possibly angiogenesis via regulation of VEGF

Human Angiopoietin-Like 4 (ANGPTL4) interaction partners

  1. enhanced expression of angiopoietin-like 4 in rheumatoid arthritis may explain the occurrence of insulin (显示 INS 抗体) resistance, cardiovascular risk, and joint destruction [review]

  2. Neither serum nor urine Angptl4 appear to be good biomarkers in minimal change disease. Elevated urinary Angptl4 in glomerular disease appears to reflect the degree of proteinuria rather than any specific disease.

  3. results reveal that liganded GR spatiotemporally controls ANGPTL4 transcription in a chromosomal context.

  4. analyzed samples from our previously published studies on ANGPL4 levels in patients on hemodialysis and patients with diabetes type 2. These samples did not show false positive reactions. The levels of ANGPTL4 were comparable to those detected previously

  5. Oleic acid enhances head and neck squamous cell carcinoma metastasis through the ANGPTL4/fibronectin (显示 FN1 抗体)/Rac1/Cdc42 (显示 CDC42 抗体) and ANGPTL4/fibronectin (显示 FN1 抗体)/MMP-9 (显示 MMP9 抗体) signaling axes.

  6. Cyclic stretching of tendon fibroblasts stimulated the expression and release of ANGPTL4 protein.

  7. ANGPTL4 is secreted by human forearm muscle in postprandial conditions after a high-saturated fatty acid meal. Plasma ANGPTL4 concentrations were not associated with in vivo skeletal muscle LPL (显示 LCP1 抗体) activity after a high-saturated fatty acid meal. Dietary fat quality affects plasma ANGPTL4, but it remains to be elucidated whether this influences short-term skeletal muscle lipid handling.

  8. angiopoietin-like 4 plays an important role in the regulation of epidermal growth factor (显示 EGF 抗体) induced cancer metastasis

  9. our data shows that ANGPTL3 (显示 ANGPTL3 抗体), 4 and 8 are increased in obesity and type 2 diabetes (T2D). ANGPTL8 associates with ANGPTL3 (显示 ANGPTL3 抗体) in the non-diabetic subjects while it associated more with ANGPTL4 in the obese and T2D subjects.

  10. Beyond rare-variant genetic association study determined rare hypertriglyceridemia causal ANGPTL4 variants based on high throughput sequencing.

Pig (Porcine) Angiopoietin-Like 4 (ANGPTL4) interaction partners

  1. The ANGPTL4 G/A polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) showed a significant effect on intramuscular fat

Zebrafish Angiopoietin-Like 4 (ANGPTL4) interaction partners

  1. These results suggest that the microbiota might regulate host intestinal Angptl4 protein expression and peripheral fat storage by suppressing the activity of an intestine-specific transcriptional enhancer.

ANGPTL4 抗原简介

Antigen Summary

This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.

Alternative names and synonyms associated with ANGPTL4

  • angiopoietin-like 4 (ANGPTL4) 抗体
  • Angiopoietin-related protein 4 (angl4) 抗体
  • angiopoietin 4 (ANGPT4) 抗体
  • angiopoietin-like 4 (Angptl4) 抗体
  • angiopoietin-like 4 (angptl4) 抗体
  • ANGPTL2 抗体
  • ANGPTL4 抗体
  • ARP4 抗体
  • Bk89 抗体
  • fiaf 抗体
  • HFARP 抗体
  • im:7144703 抗体
  • Ng27 抗体
  • NL2 抗体
  • PGAR 抗体
  • Pgarg 抗体
  • pp1158 抗体
  • si:rp71-39b20.7 抗体

Protein level used designations for ANGPTL4

angiopoietin-like 4 , Angiopoietin-related protein 4 , angiopoietin-related protein 4-like , ANG-4 , angiopoietin-4 , angiopoietin-like protein 4 , 425O18-1 , angiopoietin-related protein 4 , fasting-induced adipose factor , fibrinogen/angiopoietin-related protein , hepatic fibrinogen/angiopoietin-related protein , major histocompatibility complex region NG27 , secreted protein Bk89 , PPARG angiopoietin related protein , hepatic angiopoietin-related protein , peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein , HFARP , PPARG angiopoietin-related protein , angiopoietin-like secreted glycoprotein 4 , angiopoietin-like 4 protein

GENE ID SPECIES
476724 Canis lupus familiaris
743667 Pan troglodytes
769087 Gallus gallus
100194912 Salmo salar
100415086 Callithrix jacchus
100438448 Pongo abelii
617915 Bos taurus
57875 Mus musculus
51129 Homo sapiens
362850 Rattus norvegicus
397628 Sus scrofa
509963 Bos taurus
100860916 Capra hircus
492647 Danio rerio
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