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CA9 Protein (AA 38-414) (His tag)

CA9 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
产品编号 ABIN2180677
发货至: 中国
  • 抗原 See all CA9 蛋白
    CA9 (Carbonic Anhydrase IX (CA9))
    蛋白类型
    Recombinant
    产品特性
    AA 38-414
    宿主
    • 20
    • 7
    • 2
    • 2
    资源
    • 19
    • 6
    • 4
    • 1
    • 1
    HEK-293 Cells
    标记
    This CA9 protein is labelled with His tag.
    序列
    AA 38-414
    产品特性
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.2 kDa. The protein migrates as 53-54 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    纯度
    >90 % as determined by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CA9 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    20 mM MES, 100 mM NaCl, pH 6.5
    注意事项
    Please avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • 抗原
    CA9 (Carbonic Anhydrase IX (CA9))
    别名
    Carbonic Anhydrase IX (CA9 产品)
    别名
    CA9 Protein, CAIX Protein, Ca9 Protein, MN/CA9 Protein, MN Protein, carbonic anhydrase 9 Protein, CA9 Protein, CAH9 Protein, Car9 Protein
    背景
    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (α, β, γ, δ and ε). Carbonic anhydrase 9 (CA9 / CAIX) is also known as Membrane antigen MN (MN), Renal cell carcinoma-associated antigen G250, which belongs to the alpha-carbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CA-IX appears to be a novel specific biomarker for a cervical neoplasia.
    分子量
    41.7 kDa
    NCBI登录号
    NP_001207
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