anti-BRE (BRE) 抗体产品概述

Full name:
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) 抗体 (BRE)
在www.antibodies-online.cn可供62 Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) 抗体的19不同的供货商。 再加上,我们可以发BRE 蛋白 (11)和数多这个蛋白质的别的产品。 总共78 BRE产品已列进来了。
别名:
6030405P19Rik, AI429776, B830038C02Rik, BRCC4, BRCC45, BRE, im:7141046, LOC100231620, zgc:110368

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引用最多的anti-BRE 抗体

  1. Human Polyclonal BRE Primary Antibody for WB - ABIN2801968 : Li, Yoo, Becker, Ali-Osman, Chan: Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid. in Biochemical and biophysical research communications 1995 (PubMed)
    Show all 4 references for 2801968

  2. Human Polyclonal BRE Primary Antibody for IHC, ELISA - ABIN1001939 : Dong, Hakimi, Chen, Kumaraswamy, Cooch, Godwin, Shiekhattar: Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. in Molecular cell 2003 (PubMed)
    Show all 3 references for 1001939

更多抗BRE的相互作用对抗体

Human Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) interaction partners

  1. High BRE and high EVI1 (显示 MECOM 抗体) expression are mutually exclusive in MLL (显示 MLL 抗体)-AF9 (显示 MLLT3 抗体)-positive acute myeloid leukemia (显示 BCL11A 抗体) patients.

  2. High BRE expression defines a novel subtype of adult acute myeloid leukemia (显示 BCL11A 抗体) characterized by a favorable prognosis.

  3. NBA1/MERIT40 (显示 BABAM1 抗体) and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36 (显示 BRCC3 抗体)-containing complexes

  4. overexpression of the BRE gene is predominantly found in MLL (显示 MLL 抗体)-rearranged AML (显示 RUNX1 抗体) with t(9;11)(p22 (显示 DYNC1H1 抗体);q23).

  5. A novel stress-responsive gene called BRE which interacts with TNF (显示 TNF 抗体)-receptor-1 and blocks the apoptotic effect of TNF-alpha (显示 TNF 抗体), was identified.

  6. These results show that BRE over-expression can indeed promote growth, though not initiation, of liver tumors.

  7. BRE mediates antiapoptosis by inhibiting the mitochondrial apoptotic machinery

  8. the enhanced tumor growth is more likely due to the antiapoptotic activity of BRE than any direct effect of the protein on cell proliferation

  9. Antiapoptotic in vivo; Bre levels are regulated post-transcriptionally in the liver, which is not observed in human hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) and non-HCC (显示 FAM126A 抗体) cell lines.

  10. results implied that BRE plays a significant role in mediating antiapoptotic and proliferative responses in esophageal carcinoma cells

Mouse (Murine) Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) interaction partners

  1. results demonstrate a role for BRE in both replicative senescence and DNA damage-induced premature senescence. This can be attributed to BRE being required for BRCA1-A complex-driven HR DNA repair

  2. Depletion of BRE also increased tumor cell apoptosis, and decreased both local and metastatic tumor growth.

  3. BRE has a role in the regulation of key proteins of the cellular stress-response machinery, including prohibitin (显示 PHB 抗体) and p53 (显示 TP53 抗体)

BRE 抗原简介

Antigen Summary

Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin (By similarity).

Alternative names and synonyms associated with BRE

  • brain and reproductive organ-expressed (TNFRSF1A modulator) (bre) 抗体
  • brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE) 抗体
  • brain and reproductive organ-expressed (TNFRSF1A modulator) (LOC100231620) 抗体
  • brain and reproductive organ-expressed (TNFRSF1A modulator) (LOC100347469) 抗体
  • brain and reproductive organ-expressed (TNFRSF1A modulator) (Bre) 抗体
  • brain and reproductive organ-expressed protein (Bre) 抗体
  • brain and reproductive organ-expressed protein (bre) 抗体
  • 6030405P19Rik 抗体
  • AI429776 抗体
  • B830038C02Rik 抗体
  • BRCC4 抗体
  • BRCC45 抗体
  • BRE 抗体
  • im:7141046 抗体
  • LOC100231620 抗体
  • zgc:110368 抗体

Protein level used designations for BRE

BRCA1-A complex subunit BRE , BRCA1/BRCA2-containing complex subunit 45 , Brain and reproductive organ-expressed protein , brain and reproductive organ-expressed (TNFRSF1A modulator) , BRCA1-A complex subunit BRE-like , BRCA1/BRCA2-containing complex, subunit 4 , brain and reproductive organ-expressed protein

GENE ID SPECIES
448242 Xenopus (Silurana) tropicalis
459112 Pan troglodytes
475711 Canis lupus familiaris
702365 Macaca mulatta
100231620 Taeniopygia guttata
100347469 Oryctolagus cuniculus
100396239 Callithrix jacchus
100583596 Nomascus leucogenys
9577 Homo sapiens
362704 Rattus norvegicus
614152 Bos taurus
421417 Gallus gallus
100171610 Pongo abelii
444077 Xenopus laevis
107976 Mus musculus
550474 Danio rerio
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