anti-犬 MAP3K3 抗体 for Western Blotting

Recommended MAP3K3 Antibody (supplied by: Log in to see )

抗原
Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) 抗体
  • MAPKKK3
  • MEKK3
  • AW548911
  • Mekk3
  • mKIAA4031
  • mitogen activated protein kinase kinase kinase 3
  • mitogen-activated protein kinase kinase kinase 3
  • Map3k3
  • MAP3K3
  • map3k3
抗原表位
AA 27-135
14
11
10
9
7
4
3
3
3
2
1
1
1
1
1
适用
犬, 人, 小鼠, 大鼠
41
36
9
1
1
1
1
1
1
1
1
宿主
小鼠
52
8
克隆类型
单克隆
标记
This MAP3K3 antibody is un-conjugated
2
2
2
2
2
2
应用范围
Immunofluorescence (IF), Western Blotting (WB)
58
22
11
9
6
2
1
1
1
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产品编号 ABIN968366
产品在该地区无法提供。
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1873004 ABIN968365 IF WB Mouse IgG1 AA 27-135 Log in to see 40-MEKK3 2

引用最多的anti-MAP3K3 抗体 for Western Blotting

Similar anti-MAP3K3 抗体

应用范围 / 适用 小鼠 大鼠
Immunofluorescence (fixed cells) (IF/ICC) 1 抗体 1 抗体 1 抗体
Western Blotting (WB) 35 抗体 41 抗体 10 抗体 2 抗体
Proximity Ligation Assay (PLA) 1 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 抗体 8 抗体 5 抗体
Immunohistochemistry (IHC) 7 抗体 7 抗体 3 抗体
Immunofluorescence (IF) 7 抗体 6 抗体 4 抗体 2 抗体

General

抗原 Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) 抗体
抗原表位 AA 27-135
(14), (11), (10), (9), (7), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
适用 犬, 人, 小鼠, 大鼠
(41), (36), (9), (1), (1), (1), (1), (1), (1), (1), (1)
宿主 小鼠
(52), (8)
克隆类型 (克隆位点)
单克隆   ( )
标记 This MAP3K3 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
应用范围 Immunofluorescence (IF), Western Blotting (WB)
(58), (22), (11), (9), (6), (2), (1), (1), (1)
Pubmed 2个引用可参考
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MAP3K3抗体详情

MAP3K3目标详情 使用细节 贮存及处理 ProductDetails: References for anti-MAP3K3 antibody (ABIN968366) 图像
交叉反应 小鼠, 大鼠, 犬
产品特性 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols.
纯化方法 The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
免疫原 Human MEKK3 aa. 27-135
克隆位点 40-MEKK3
亚型 IgG1

MAP3K3目标详情

MAP3K3抗体详情 使用细节 贮存及处理 ProductDetails: References for anti-MAP3K3 antibody (ABIN968366) 图像 回页首
抗原
别名 MEKK3 (MAP3K3 Antibody 摘要)
背景 The Ras signaling pathway links signals from growth factor receptors to activation of the MEK/ERK kinases. This cascade of phosphorylation leads to cell growth and differentiation. External stimuli such as endotoxins, UV irradiation, heat, and hyperosmolarity, induce an array of cellular responses that culminate with gene expression. These processes are controlled by the MKK3/p38MAP kinase cascade. A third pathway responsive to environmental stress, cell death, or apoptosis is regulated by SEK/SAPKs. When overexpresssed, MEKK3 is a kinase that is capable of activating both the ERK and SAPK cascades. MEKK3 is 626 amino acids long and is ubiquitously expressed. It is positioned upstream of SEK and MEK in the signaling pathways and directly phosphorylates these enzymes. Overexpression of MEKK3 results in the activation of NFkappaB. Thus, MEKK3 represents an emerging family of kinases that is capable of inducing more than one signaling pathway. This indicates that specificity in the signaling cascades is probably achieved by effector kinases such as the ERKs and SAPKs.
分子量 71 kDa
研究领域 Immunology, Innate Immunity, Kinases/Phosphatases
途径 MAPK Pathway

使用细节

MAP3K3抗体详情 MAP3K3目标详情 贮存及处理 ProductDetails: References for anti-MAP3K3 antibody (ABIN968366) 图像 回页首
说明

Related Products: ABIN967389, ABIN968535

限制 仅限研究用

贮存及处理

MAP3K3抗体详情 MAP3K3目标详情 使用细节 ProductDetails: References for anti-MAP3K3 antibody (ABIN968366) 图像 回页首
状态 Liquid
浓度 250 μg/mL
缓冲液 Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store undiluted at -20°C.

ProductDetails: References for anti-MAP3K3 antibody (ABIN968366)

MAP3K3抗体详情 MAP3K3目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Yang, Lai, Lai, Hsu, Kuo, Yu, Lin, Yang, Kuo, Wu, Chung: "Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways." in: Anticancer research, Vol. 30, Issue 6, pp. 2135-43, 2010

Ellinger-Ziegelbauer, Brown, Kelly, Siebenlist et al.: "Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 ..." in: The Journal of biological chemistry, Vol. 272, Issue 5, pp. 2668-74, 1997

图像

MAP3K3抗体详情 MAP3K3目标详情 使用细节 贮存及处理 ProductDetails: References for anti-MAP3K3 antibody (ABIN968366) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-MAP3K3 抗体 (Mitogen-Activated Protein Kinase Kinase Kinase 3) (AA 27-135) (ABIN968366) Western blot analysis of MEKK3 on a HeLa cell lysate (Human cervical epitheloid carci...
Immunofluorescence (IF) image for anti-MAP3K3 抗体 (Mitogen-Activated Protein Kinase Kinase Kinase 3) (AA 27-135) (ABIN968366) Immunofluorescence staining of RSV-3T3 cells.
 image for anti-MAP3K3 抗体 (Mitogen-Activated Protein Kinase Kinase Kinase 3) (AA 27-135) (ABIN968366) anti-Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3) (AA 27-135) antibody (Image 3)