MAP2K3 (MAP2K3) ELISA试剂盒产品概述

Full name:
Mitogen-Activated Protein Kinase Kinase 3 ELISA试剂盒 (MAP2K3)
在www.antibodies-online.cn可供12 Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) ELISA试剂盒的4不同的供货商。 再加上,我们可以发MAP2K3 抗体 (312)MAP2K3 蛋白 (15)和数多这个蛋白质的别的产品。 总共357 MAP2K3产品已列进来了。
别名:
AW212142, map2k3, MAPKK3, MEK3, MKK3, mMKK3b, Prkmk3, SAPKK-2, SAPKK2, zMKK3
list all ELISA KIts 基因 基因ID UniProt
MAP2K3 303200  
MAP2K3 5606 P46734
MAP2K3 26397 O09110

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MAP2K3 (MAP2K3) ELISA试剂盒 by Reactivity

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适于 MAP2K3 相互作用对的更多 ELISA 试剂盒

Human Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) interaction partners

  1. The results revealed upregulation of MEK3, as well as phosphorylated MEK3 and phosphorylated p38 MAPK (显示 MAPK14 ELISA试剂盒), in CMM patients. These results provide a "fingerprint" for mechanistic studies of CMM in the future and highlight the importance of MEK3-p38 MAPK (显示 MAPK14 ELISA试剂盒) activation in CMM.

  2. miR (显示 MLXIP ELISA试剂盒)-21 targets MKK3 in vivo and in vitro, inhibiting the downstream factors IL-6 (显示 IL6 ELISA试剂盒) and TNF-alpha (显示 TNF ELISA试剂盒), in ischemia pretreatment protection from ischemia-reperfusion induced kidney injury.

  3. MKK3 overexpression upregulated the cyclin-dependent kinase (显示 CDK1 ELISA试剂盒) inhibitors, p16 INK4A and p15 INK4B (显示 CDKN2B ELISA试剂盒) in hepatocellular carcinoma cells was Bim1, was downregulated following MKK3 overexpression.

  4. Our results suggest that asthma is associated with MKK3 over-expression in CD8 (显示 CD8A ELISA试剂盒)+ cells; we have also demonstrated that MKK3 may be critical for airway neutrophilia

  5. MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3.

  6. study detected higher MKK3 activation in isolated peripheral blood mononuclear cells from septic patients compared with nonseptic controls

  7. study concludes MAP2K3 is a reproducible obesity locus that may affect body weight via complex mechanisms involving appetite regulation and hypothalamic inflammation

  8. miR-20a acts in a feedback loop to repress the expression of MKK3 and to negatively regulate the p38 pathway-mediated VEGF-induced endothelial cell migration and angiogenesis

  9. Data suggest aberrant MAP2K protein (MKK3, MKK4 (显示 MAP2K4 ELISA试剂盒), MKK6 (显示 MAP2K6 ELISA试剂盒), and MKK7 (显示 MAP2K7 ELISA试剂盒)) expression indicates that altered cellular signal transduction mediated via JNK (显示 MAPK8 ELISA试剂盒) and p38 (显示 CRK ELISA试剂盒) may be common in bladder cancer.

  10. the balance between MKK6 (显示 MAP2K6 ELISA试剂盒) and MKK3 mediates p38 MAPK (显示 MAPK14 ELISA试剂盒) associated resistance to cisplatin in NSCLC

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) interaction partners

  1. ATF3 (显示 ATF3 ELISA试剂盒) upregulation in cardiac fibroblasts in response to hypertensive stimuli protects the heart by suppressing Map2K3 expression and subsequent p38 (显示 CRK ELISA试剂盒)-transforming growth factor-beta signaling.

  2. miR (显示 MLXIP ELISA试剂盒)-21 targets MKK3 in vivo and in vitro, inhibiting the downstream factors IL-6 (显示 IL6 ELISA试剂盒) and TNF-alpha (显示 TNF ELISA试剂盒), in ischemia pretreatment protection from ischemia-reperfusion induced kidney injury.

  3. miR (显示 MLXIP ELISA试剂盒)-21a-5p inhibited BPA (显示 DST ELISA试剂盒) induced adipocyte differentiation by targeting map2k3 through MKK3/p38/MAPK (显示 MAPK14 ELISA试剂盒) in 3T3-L1 cells

  4. this study demonstrates that MKK3 influences mitochondrial quality by affecting the expression of mitochondrial proteins, including TCA cycle enzymes, and mitophagy, which consequently regulates the inflammatory response.

  5. Exendin-4 treatment improves cardiac function, attenuates cardiac remodeling, and promotes angiogenesis in the infarcted myocardium through MKK3 and Akt-1 (显示 AKT1 ELISA试剂盒) pathway.

  6. Our results suggest that asthma is associated with MKK3 over-expression in CD8 (显示 CD8A ELISA试剂盒)+ cells; we have also demonstrated that MKK3 may be critical for airway neutrophilia

  7. MKK3 and MKK6 (显示 MAP2K6 ELISA试剂盒) differentially regulate bone loss due to estrogen withdrawal. MKK3 directly mediates osteoclastogenesis while MKK6 (显示 MAP2K6 ELISA试剂盒) likely contributes to pro-inflammatory cytokine production that promotes osteoclast formation.

  8. results designate MKK3 as a novel, positive regulator of SCF (显示 KITLG ELISA试剂盒)-induced mast cell proliferation and a critical signaling protein for AP-1 (显示 JUN ELISA试剂盒)-dependent IL-6 (显示 IL6 ELISA试剂盒) production

  9. findings demonstrate a critical role for mitochondria in the pathogenesis of sepsis that involves a previously unrecognized function of MKK3 in mitochondrial quality control

  10. Endothelial MKK3 is neede for inflammatory cell recruitment to the lungs, mitochondrial oxidant-mediated AP-1 (显示 JUN ELISA试剂盒), NF-kappaB (显示 NFKB1 ELISA试剂盒) activation, & ICAM-1 (显示 ICAM1 ELISA试剂盒) expression during LPS (显示 TLR4 ELISA试剂盒) challenge.

MAP2K3 抗原简介

Antigen Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.

Alternative names and synonyms associated with MAP2K3

  • MAP kinase activator XMEK3 (map2k3) Elisa Kit
  • mitogen activated protein kinase kinase 3 (Map2k3) Elisa Kit
  • mitogen-activated protein kinase kinase 3 (MAP2K3) Elisa Kit
  • mitogen-activated protein kinase kinase 3 (Map2k3) Elisa Kit
  • mitogen-activated protein kinase kinase 6 (map2k6) Elisa Kit
  • AW212142 Elisa Kit
  • map2k3 Elisa Kit
  • MAPKK3 Elisa Kit
  • MEK3 Elisa Kit
  • MKK3 Elisa Kit
  • mMKK3b Elisa Kit
  • Prkmk3 Elisa Kit
  • SAPKK-2 Elisa Kit
  • SAPKK2 Elisa Kit
  • zMKK3 Elisa Kit

Protein level used designations for MAP2K3

MAP kinase kinase 3 , MAPK/ERK kinase 3 , MAPKK 3 , MEK 3 , SAPK kinase 2 , dual specificity mitogen-activated protein kinase kinase 3 , stress-activated protein kinase kinase 2 , mitogen activated protein kinase kinase 3 , protein kinase, mitogen-activated, kinase 3 , MAP kinase kinase 6 , MAPKK 6 , dual specificity mitogen-activated protein kinase kinase 6 , mitogen-activated protein kinase kinase 3

GENE ID SPECIES
399150 Xenopus laevis
303200 Rattus norvegicus
5606 Homo sapiens
489547 Canis lupus familiaris
26397 Mus musculus
516039 Bos taurus
416496 Gallus gallus
65239 Danio rerio
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