anti-BAD (BAD) 抗体产品概述

Full name:
anti-BCL2-Associated Agonist of Cell Death 抗体 (BAD)
在www.antibodies-online.cn可供993 BCL2-Associated Agonist of Cell Death (BAD) 抗体的32不同的供货商。 再加上,我们可以发BAD 试剂盒 (52)BAD 蛋白 (11)和数多这个蛋白质的别的产品。 总共1132 BAD产品已列进来了。
AI325008, BAD, Bbc2, BCL2L8, fa01b12, wu:fa01b12, wu:fa96d04

最受欢迎的抗anti-BAD (BAD) 抗体


抗Human BAD 抗体:

抗Mouse (Murine) BAD 抗体:

抗Rat (Rattus) BAD 抗体:

所有可销售的anti-BAD 抗体


引用最多的anti-BAD 抗体

  1. Human Polyclonal BAD Primary Antibody for EIA, IHC (p) - ABIN358087 : Hurbin, Coll, Dubrez-Daloz, Mari, Auberger, Brambilla, Favrot: Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for 358087

  2. Human Polyclonal BAD Primary Antibody for FACS, IHC (p) - ABIN388118 : Won, Kim, La, Kim, Meadows, Joe: Cleavage of 14-3-3 protein by caspase-3 facilitates bad interaction with Bcl-x(L) during apoptosis. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for 388118

  3. Human Polyclonal BAD Primary Antibody for IHC (p), WB - ABIN389520 : Antignani, Youle: A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad. in Biochemistry 2005 (PubMed)
    Show all 2 references for 389520

  4. Human Polyclonal BAD Primary Antibody for IF, IHC - ABIN1531524 : Wang, Rapp, Reed: Bcl-2 targets the protein kinase Raf-1 to mitochondria. in Cell 1997 (PubMed)

  5. Cow (Bovine) Polyclonal BAD Primary Antibody for WB - ABIN2779324 : Xia, Zhang, Du, Pan, Zhao, Sun, Hong, Liu, Fan: miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. in International journal of cancer. Journal international du cancer 2008 (PubMed)


Zebrafish BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bad functions as an essential sensitizer and Puma (显示 BBC3 抗体) as an essential activator of IR-induced mitochondrial apoptosis specifically in embryonic neural tissue.

  2. Stage-specific expression of TNFalpha (显示 TNF 抗体) regulates bad/bid (显示 BID 抗体)-mediated apoptosis and RIP1 (显示 RALBP1 抗体)/ROS (显示 ROS1 抗体)-mediated secondary necrosis in Birnavirus-infected fish cells.

  3. Results indicate that zebrafish BH3-only (显示 BBC3 抗体) proapoptotic protein (BAD) could induce apoptosis in vitro and in vivo and may have biological implications in apoptosis during zebrafish development.

Human BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. The long unstructured region of Bcl-xl (显示 BCL2L1 抗体) modulates its structural dynamics.

  2. Short-term treatment of nascent melanoma tumors with PAK inhibitors that block RhoJ (显示 RHOJ 抗体) signaling halts the growth of BRAF (显示 BRAF 抗体) mutant melanoma tumors in vivo and induces apoptosis in melanoma cells in vitro via a BAD-dependent mechanism. As up to 50% of BRAF (显示 BRAF 抗体) mutant human melanomas express high levels of RhoJ (显示 RHOJ 抗体), these studies nominate the RhoJ (显示 RHOJ 抗体)-BAD signaling network as a therapeutic vulnerability for fledgling BRAF (显示 BRAF 抗体) mutant human tumor

  3. Recent studies that combine experiments in yeast and in mammalian cells have shown the unexpected effect of the anti-apoptotic protein Bcl-xL (显示 BCL2L1 抗体) on the priming of Bax (显示 BAX 抗体). As demonstrated with the BH3-mimetic molecule ABT-737, this property of Bcl-xL (显示 BCL2L1 抗体), and of Bcl-2 (显示 BCL2 抗体), is crucial to elaborate about how apoptosis could be reactivated in tumoral cells.

  4. the accumulation of reactive oxygen species (ROS (显示 ROS1 抗体)) in cells expressing JAK2V617F compromises the NHE-1 (显示 SLC9A1 抗体)/Bcl-xL (显示 BCL2L1 抗体) deamidation pathway by repressing NHE-1 (显示 SLC9A1 抗体) upregulation in response to DNA damage. hematopoietic stem cells (HSCs), FOXO3A (显示 FOXO3 抗体) is largely localized within the nuclei despite the presence of JAK2V617F mutation, suggesting that JAK2 (显示 JAK2 抗体)-FOXO (显示 FOXO3 抗体) signaling has a different effect on progenitors compared with stem cells.

  5. These results identify beta3 integrin (显示 ITGB3 抗体) signaling via repression of BAD as an important survival pathway used by breast cancer cells to evade chemotherapy induced stress.

  6. miR (显示 MLXIP 抗体)-377 was markedly downregulated in HCC (显示 FAM126A 抗体) cell lines and primary human HCC (显示 FAM126A 抗体) tissues. The decreased expression of miR (显示 MLXIP 抗体)-377 contributes to the upregulation of Bcl-xL (显示 BCL2L1 抗体) expression by targeting its 3'-untranslated region (3'-UTR (显示 UTS2R 抗体)).

  7. By the pharmacologic targeting of BCL2 (显示 BCL2 抗体), MCL1 (显示 MCL1 抗体), and BCL-XL (显示 BCL2L1 抗体), we demonstrated that diffuse large B-cell lymphoma can be divided into BCL2 (显示 BCL2 抗体)-dependent and MCL1 (显示 MCL1 抗体)-dependent subgroups with a less pronounced role left for BCL-XL (显示 BCL2L1 抗体).

  8. increased platelet apoptosis and activation as well as reduced expression of Bcl-xL (显示 BCL2L1 抗体), increased expression of Bax (显示 BAX 抗体) and caspase-3 (显示 CASP3 抗体) activity were found in platelets after treated with ITP (显示 ITPA 抗体) plasma in comparison with control plasma.

  9. These findings demonstrated that Akt (显示 AKT1 抗体) is related to NF-kappaB (显示 NFKB1 抗体) and Bad signaling pathway possibly playing a direct role in the progression of liver cancer. Thus, Akt (显示 AKT1 抗体) might be an important and potential treatment choice for the clinical diagnosis and treatment in the future.

  10. Bh3 domain induced conformational changes in Bcl-Xl (显示 BCL2L1 抗体) revealed by crystal structure and comparative analysis.

Mouse (Murine) BCL2-Associated Agonist of Cell Death (BAD) interaction partners

  1. Bad is dispensable for TNF (显示 TNF 抗体)-mediated cell death.

  2. Results indicate the downstream targets of insulin (显示 INS 抗体), cyclin D1 (显示 CCND1 抗体), BAD, alpha-MHC (显示 MYH6 抗体), and GATA-4 (显示 GATA4 抗体), elucidate a molecular mechanism of insulin (显示 INS 抗体) in promoting cell proliferation and differentiation.

  3. our study suggests that Bad and Bmf (显示 BMF 抗体) co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis.

  4. Results reveal that IKK (显示 CHUK 抗体) inhibits TNFalpha (显示 TNF 抗体)-induced apoptosis through two distinct but cooperative mechanisms: activation of the survival factor NF-kappaB (显示 NFKB1 抗体) and inactivation of the proapoptotic BH3-only (显示 BBC3 抗体) BAD protein.

  5. RNAi-mediated silencing of STAT1 (显示 STAT1 抗体) in soft tissue sarcoma (STS (显示 STS 抗体)) cells was sufficient to increase expression of the apoptotic mediators Fas (显示 FAS 抗体) and Bad and to elevate the sensitivity of STS (显示 STS 抗体) cells to Fas (显示 FAS 抗体)-mediated apoptosis

  6. Tonicity-induced COX-2 (显示 COX2 抗体) expression and PGE2 synthesis in the renal medulla entails phosphorylation and inactivation of the pro-apoptotic protein Bad, thereby counteracting apoptosis in renal medullary epithelial cells.

  7. Caspase-3 (显示 CASP3 抗体) is activated by the BAD-BAX (显示 BAX 抗体) cascade resulting in long term depression induction in the hippocampus.

  8. JNK1 (显示 MAPK8 抗体) is required for erythropoietin (显示 EPO 抗体)-mediated cell survival through phosphorylation and inactivation of the pro-apoptotic, Bcl-2 (显示 BCL2 抗体) homology domain 3 (BH3)-only (显示 BBC3 抗体) Bcl-associated death protein (Bad).

  9. Bad protein cooperate with bim (显示 BCL2L11 抗体) protein in certain apoptotic responses and in the suppression of g-irradiation-induced thymic lymphoma.(Bad protein)

  10. Data show that loss of Bmf (显示 BMF 抗体) reduced the pressure to inactivate p53 (显示 TP53 抗体), whereas Bad deficiency did not, identifying Bmf (显示 BMF 抗体) as a novel component of the p53 (显示 TP53 抗体)-independent tumor suppressor pathway triggered by c-Myc (显示 MYC 抗体).

Cow (Bovine) BCL2-Associated Agonist of Cell Death (BAD) interaction partners

BAD 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Alternative names and synonyms associated with BAD

  • BCL2-antagonist of cell death b (badb) 抗体
  • BCL2-associated agonist of cell death (BAD) 抗体
  • BCL2-associated agonist of cell death (Bad) 抗体
  • AI325008 抗体
  • BAD 抗体
  • Bbc2 抗体
  • BCL2L8 抗体
  • fa01b12 抗体
  • wu:fa01b12 抗体
  • wu:fa96d04 抗体

Protein level used designations for BAD

proapoptotic BH3-only protein , BCL2-antagonist of cell death , BCL2-associated agonist of cell death , BCL-X/BCL-2 binding protein , BCL2-antagonist of cell death protein , BCL2-binding component 6 , BCL2-binding protein , bcl-2-binding component 6 , bcl-2-like protein 8 , bcl-XL/Bcl-2-associated death promoter , bcl2 antagonist of cell death , bcl2-L-8 , Bcl-associated death promoter , bcl-xL/Bcl-2-associated death promoter , Bcl2-antagonist of cell death , bcl-2 associated death agonist , bcl2-associated death promoter

58100 Danio rerio
768269 Felis catus
780444 Ovis aries
572 Homo sapiens
12015 Mus musculus
64639 Rattus norvegicus
483763 Canis lupus familiaris
615013 Bos taurus
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