anti-HCLS1 (HCLS1) 抗体产品概述

Full name:
anti-Hematopoietic Cell-Specific Lyn Substrate 1 抗体 (HCLS1)
在www.antibodies-online.cn可供130 Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) 抗体的20不同的供货商。 再加上,我们可以发HCLS1 试剂盒 (8)HCLS1 蛋白 (7)和数多这个蛋白质的别的产品。 总共151 HCLS1产品已列进来了。
别名:
AW213261, CTTNL, GW128, hcls1, HS1, KCIP-1, si:dkey-9a20.6, wu:fk96b08, YWHAA, zgc:154014
列出全部抗体 基因 基因ID UniProt
HCLS1 15163 P49710
HCLS1 288077  
HCLS1 3059 P14317

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引用最多的anti-HCLS1 抗体

  1. Human Monoclonal HCLS1 Primary Antibody for IF, IP - ABIN968026 : Fukuda, Kitamura, Taniuchi, Maekawa, Benhamou, Sarthou, Watanabe: Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate. in Proceedings of the National Academy of Sciences of the United States of America 1995 (PubMed)
    Show all 3 references for 968026

  2. Cow (Bovine) Polyclonal HCLS1 Primary Antibody for IHC, WB - ABIN2777502 : Ruzzene, Penzo, Pinna: Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. in The Biochemical journal 2002 (PubMed)
    Show all 2 references for 2777502

  3. Cow (Bovine) Polyclonal HCLS1 Primary Antibody for WB - ABIN2779751 : Barcroft: The Oxygen Tension in the Submaxillary Glands and certain other tissues. in The Biochemical journal 2006 (PubMed)
    Show all 2 references for 2779751

  4. Human Polyclonal HCLS1 Primary Antibody for IHC (p), WB - ABIN657959 : Muzio, Scielzo, Frenquelli, Bachi, De Palma, Alessio, Ghia, Caligaris-Cappio: HS1 complexes with cytoskeleton adapters in normal and malignant chronic lymphocytic leukemia B cells. in Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007 (PubMed)
    Show all 2 references for 657959

  5. Human Monoclonal HCLS1 Primary Antibody for IF, ELISA - ABIN561238 : Kan, Wen, Pasquier, Jankowski, Chang, Richards, Kavallaris, MacKenzie: Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization. in Oncogene 2012 (PubMed)

更多抗HCLS1的相互作用对抗体

Mouse (Murine) Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) interaction partners

  1. HS1 as an important regulator of proper Rac1 and Rap1 activation and neutrophil extravasation.

  2. Results identified two proteins P23 (显示 CDK5R1 抗体) and HCLS1, which were not known as RNA-binding proteins, exhibiting RNA-binding activity.

  3. Phosphoproteome analyses reveal specific implications of Hcls1, p21-activated kinase 1 (显示 PAK1 抗体) and Ezrin (显示 EZR 抗体) in proliferation of a myeloid progenitor cell line downstream of wild-type and ITD mutant Fms-like tyrosine kinase 3 (显示 FLT3 抗体) receptors.

  4. studies show that HS1 promotes an early step in the endocytic pathway that is required for efficient Ag presentation of exogenous Ag by dendritic cells

  5. Studies show that HS1 functions in concert with WASp (显示 WASL 抗体) to fine-tune DC cytoarchitecture and direct cell migration.

  6. In vivo, immunodeficient Rag2 (显示 RAG2 抗体)(-/-)gamma(c)(-/-) mice injected with HS1-silenced CLL B cells showed a decreased organ infiltration with the notable exception of the bone marrow.

  7. Hematopoietic lineage cell specific protein 1 (显示 SP1 抗体) plays a significant functional role in platelet activation downstream of glycoprotein VI and protease-activated receptors[Hematopoietic lineage cell specific protein 1 (显示 SP1 抗体)]

  8. data indicate that Syk (显示 SYK 抗体) kinase plays an important role in the translocation of hematopoietic lineage cell-specific protein 1 (显示 SP1 抗体) (HS1) into lipid rafts

  9. This study concludes that HS1 does not play a major role in platelet function. It is possible that a role for HS1 is masked by the presence of cortactin (显示 CTTN 抗体).

  10. tyrosine phosphorylation of HS1 occurs downstream of both PAR-1 (显示 MARK2 抗体) and PAR-4 (显示 F2RL3 抗体). HS1 phosphorylation is a Gq mediated response regulated by Src (显示 SRC 抗体) kinases

Human Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1) interaction partners

  1. Data show that 14-3-3beta protein augmented the expression of matrix metalloproteinasea MMP2 (显示 MMP2 抗体) and MMP9 (显示 MMP9 抗体) through PI3 kinase (显示 PIK3CA 抗体)/Akt (显示 AKT1 抗体) protein/NF-kappaappa B pathway, thereby enhancing the invasiveness of hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) cells.

  2. These findings indicate that 14-3-3beta and gamma are novel PPARgamma2 (显示 PPARG 抗体) regulators and are involved in hepatic lipid metabolism. 14-3-3b and gamma can be therapeutic target molecules to treat non-alcoholic fatty liver disease.

  3. SDF1alpha-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells.

  4. miR (显示 MLXIP 抗体)-152 controls both the expression of 14-3-3beta and HLA-G (显示 HLAG 抗体) and exerts a dual role in tumor cells by both altering the immunogenicity and the tumorigenicity

  5. Data suggest that serum 14-3-3beta concentrations may constitute a useful marker for blood brain barrier damage severity and follow up in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis.

  6. Using gene reporter assays, we show that promoter variations in 11 intrinsic apoptosis genes, including ADPRT (显示 PARP1 抗体), APAF1 (显示 APAF1 抗体), BCL2 (显示 BCL2 抗体), BAD, BID (显示 BID 抗体), MCL1 (显示 MCL1 抗体), BIRC4 (显示 XIAP 抗体), BCL2L1 (显示 BCL2L1 抗体), ENDOG (显示 ENDOG 抗体), YWHAB (显示 YWHAB 抗体), and YWHAQ (显示 YWHAQ 抗体), influence promoter activity in an allele-specific manner.

  7. Crystal structure of Myo1c (显示 MYO1C 抗体)/14-3-3beta complex, which has been implicated in the exocytosis of glucose transporter 4 storage vesicles during insulin (显示 INS 抗体)-stimulated glucose uptake.

  8. Data identified three classes of 14-3-3 (显示 YWHAQ 抗体) targets that all have two binding sites, but displayed synergistic interaction between converging signalling pathways for different ranges of parameter values.

  9. Phosphoproteome analyses reveal specific implications of Hcls1, p21-activated kinase 1 (显示 PAK1 抗体) and Ezrin (显示 EZR 抗体) in proliferation of a myeloid progenitor cell line downstream of wild-type and ITD mutant Fms-like tyrosine kinase 3 (显示 FLT3 抗体) receptors.

  10. These results indicate that the six YWHAB (显示 YWHAB 抗体) polymorphisms are not associated with the genetic susceptibility to sporadic Creutzfeldt-Jakob disease.

HCLS1 抗原简介

Antigen Summary

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

Alternative names and synonyms associated with HCLS1

  • hematopoietic cell-specific Lyn substrate 1 (HCLS1) 抗体
  • hematopoietic cell-specific Lyn substrate 1 (LOC100223649) 抗体
  • hematopoietic cell-specific Lyn substrate 1 (LOC100340933) 抗体
  • Hematopoietic lineage cell-specific protein (hcls1) 抗体
  • hematopoietic cell specific Lyn substrate 1 (Hcls1) 抗体
  • hematopoietic cell-specific Lyn substrate 1 (hcls1) 抗体
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAB) 抗体
  • AW213261 抗体
  • CTTNL 抗体
  • GW128 抗体
  • hcls1 抗体
  • HS1 抗体
  • KCIP-1 抗体
  • si:dkey-9a20.6 抗体
  • wu:fk96b08 抗体
  • YWHAA 抗体
  • zgc:154014 抗体

Protein level used designations for HCLS1

hematopoietic cell-specific Lyn substrate 1 , hematopoietic lineage cell-specific protein , hematopoietic lineage cell-specific protein-like , Hematopoietic lineage cell-specific protein , hematopoietic cell-specific LYN substrate 1 , lckBP1 , p75 , fk96b08 , uncharacterized protein LOC563056 , 14-3-3 alpha , 14-3-3 protein beta/alpha , brain protein 14-3-3, beta isoform , protein 1054 , protein kinase C inhibitor protein 1 , protein kinase C inhibitor protein-1 , tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide

GENE ID SPECIES
460623 Pan troglodytes
714044 Macaca mulatta
100223649 Taeniopygia guttata
100340933 Oryctolagus cuniculus
100411356 Callithrix jacchus
100479773 Ailuropoda melanoleuca
100521992 Sus scrofa
100598393 Nomascus leucogenys
100196789 Salmo salar
15163 Mus musculus
288077 Rattus norvegicus
3059 Homo sapiens
100684969 Canis lupus familiaris
508445 Bos taurus
563056 Danio rerio
426867 Gallus gallus
7529 Homo sapiens
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