电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

HCLS1 产品

(Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Categories

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured HCLS1 Categories

HCLS1 抗体

High quality antibodies with extensive validation data.

HCLS1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HCLS1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), PLA, RNAi
Validations
  • (7)
Cat. No. ABIN516371
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (1)
  • (9)
Cat. No. ABIN2777503
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (5)
Cat. No. ABIN516375
Quantity 100 μg
Datasheet Datasheet

Recommended HCLS1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1136285
Quantity 96 tests
Datasheet Datasheet

Recommended HCLS1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306431
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306429
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3081211
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HCLS1 Products

Mukherjee, Kim, Mooren, Shahan, Cohan, Cooper: "Role of cortactin homolog HS1 in transendothelial migration of natural killer cells." in: PLoS ONE, Vol. 10, Issue 2, pp. e0118153, (2015) (PubMed).

Lettau, Kabelitz, Janssen: "SDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells." in: European journal of immunology, Vol. 45, Issue 2, pp. 551-61, (2015) (PubMed).

Kan, Wen, Pasquier, Jankowski, Chang, Richards, Kavallaris, MacKenzie: "Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization." in: Oncogene, Vol. 31, Issue 46, pp. 4815-27, (2012) (PubMed).

Ruzzene, Penzo, Pinna: "Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells." in: The Biochemical journal, Vol. 364, Issue Pt 1, pp. 41-7, (2002) (PubMed).

Takemoto, Furuta, Li, Strong-Sparks, Hashimoto: "LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck." in: The EMBO journal, Vol. 14, Issue 14, pp. 3403-14, (1995) (PubMed).

Fukuda, Kitamura, Taniuchi, Maekawa, Benhamou, Sarthou, Watanabe: "Restoration of surface IgM-mediated apoptosis in an anti-IgM-resistant variant of WEHI-231 lymphoma cells by HS1, a protein-tyrosine kinase substrate." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 16, pp. 7302-6, (1995) (PubMed).

Yamanashi, Okada, Semba, Yamori, Umemori, Tsunasawa, Toyoshima, Kitamura, Watanabe, Yamamoto: "Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3631-5, (1993) (PubMed).

Synonyms and alternative names related to HCLS1

hematopoietic cell-specific Lyn substrate 1 (HCLS1), hematopoietic cell specific Lyn substrate 1 (Hcls1), hematopoietic lineage cell-specific protein-like (LOC100223649), hematopoietic cell-specific Lyn substrate 1 (hcls1), hematopoietic cell-specific Lyn substrate 1 (Hcls1), AW213261, CTTNL, HCLS1, hcls1, HS1, si:dkey-9a20.6, wu:fk96b08, zgc:154014

Protein level used designations for HCLS1

  • hematopoietic lineage cell-specific protein
  • lckBP1
  • p75
  • hematopoietic cell-specific LYN substrate 1
  • hematopoietic cell-specific Lyn substrate 1
  • hematopoietic lineage cell-specific protein-like
  • Hematopoietic lineage cell-specific protein
  • fk96b08
  • uncharacterized protein LOC563056
You are here:
客服