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HCN1 产品

(Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

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The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011].

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Featured HCN1 Categories

HCN1 抗体

High quality antibodies with extensive validation data.

HCN1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HCN1 抗体

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Cat. No. ABIN361763
Quantity 100 μg
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Cat. No. ABIN2483966
Quantity 100 μg
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Cat. No. ABIN2483965
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Recommended HCN1 ELISA试剂盒

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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
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Cat. No. ABIN6210510
Quantity 96 tests
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Recommended HCN1 蛋白

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Cat. No. ABIN7123393
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Cat. No. ABIN3081371
Quantity 1 mg
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Reactivity Mouse
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Cat. No. ABIN3132195
Quantity 1 mg
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Latest Publications for our HCN1 Products

Zhou, Lin, Si, Ru, Chen, Xiao, Li: "Downregulation of HCN1 channels in hippocampus and prefrontal cortex in methamphetamine re-exposed mice with enhanced working memory." in: Physiological research, Vol. 68, Issue 1, pp. 107-117, (2019) (PubMed).

Luo, Chen, Lu, Fu, Lu, Xu, Li, He, Guo: "Baclofen ameliorates spatial working memory impairments induced by chronic cerebral hypoperfusion via up-regulation of HCN2 expression in the PFC in rats." in: Behavioural brain research, Vol. 308, pp. 6-13, (2016) (PubMed).

Luo, Lu, Li, Zhou, Chen, Lu, Xu, He, Guo: "Long-lasting spatial learning and memory impairments caused by chronic cerebral hypoperfusion associate with a dynamic change of HCN1/HCN2 expression in hippocampal CA1 region." in: Neurobiology of learning and memory, Vol. 123, pp. 72-83, (2015) (PubMed).

Weltzien, Percival, Martin, Grünert: "Analysis of bipolar and amacrine populations in marmoset retina." in: The Journal of comparative neurology, Vol. 523, Issue 2, pp. 313-34, (2014) (PubMed).

Zhang, Bonnan, Bony, Ferezou, Pietropaolo, Ginger, Sans, Rossier, Oostra, LeMasson, Frick: "Dendritic channelopathies contribute to neocortical and sensory hyperexcitability in Fmr1(-/y) mice." in: Nature neuroscience, Vol. 17, Issue 12, pp. 1701-9, (2014) (PubMed).

Pan, Bhattarai, Modestou, Drack, Chetkovich, Baker: "TRIP8b is required for maximal expression of HCN1 in the mouse retina." in: PLoS ONE, Vol. 9, Issue 1, pp. e85850, (2014) (PubMed).

Liu, Manis, Davis: "I h and HCN channels in murine spiral ganglion neurons: tonotopic variation, local heterogeneity, and kinetic model." in: Journal of the Association for Research in Otolaryngology : JARO, Vol. 15, Issue 4, pp. 585-99, (2014) (PubMed).

Kupferman, Basu, Russo, Guevarra, Cheung, Siegelbaum: "Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment." in: Cell, Vol. 158, Issue 6, pp. 1335-47, (2014) (PubMed).

Li, Lu, Zhou, Zong, Li, Xu, Guo, Lu: "Activation of GABAB receptors ameliorates cognitive impairment via restoring the balance of HCN1/HCN2 surface expression in the hippocampal CA1 area in rats with chronic cerebral hypoperfusion." in: Molecular neurobiology, Vol. 50, Issue 2, pp. 704-20, (2014) (PubMed).

Zhou, Luo, Lu, Li, Wang, Lu, Xu, He, Guo: "Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 56, pp. 207-14, (2014) (PubMed).

Synonyms and alternative names related to HCN1

hyperpolarization activated cyclic nucleotide gated potassium channel 1 (hcn1), hyperpolarization activated cyclic nucleotide gated potassium channel 1 (HCN1), hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 (Hcn1), hyperpolarization-activated, cyclic nucleotide-gated K+ 1 (Hcn1), BCNG-1, BCNG1, Bcng1, C630013B14Rik, HAC-2, HAC2

Protein level used designations for HCN1

  • hyperpolarization activated cyclic nucleotide-gated potassium channel 1
  • brain cyclic nucleotide gated channel 1
  • brain cyclic nucleotide-gated channel 1
  • potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
  • hyperpolarization-activated cyclic nucleotide-gated channel 1
  • rbHCN1
  • BCNG-1
  • HAC-2
  • hyperpolarization-activated cation channel 2
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