anti-人 EIF2AK2 抗体 for Immunoprecipitation

Recommended EIF2AK2 Antibody (supplied by: Log in to see )

抗原
Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) 抗体
  • PKR
  • pkr
  • EIF2AK2
  • DKFZp469K1934
  • EIF2AK1
  • PRKR
  • 2310047A08Rik
  • 4732414G15Rik
  • AI467567
  • AI747578
  • Pkr
  • Prkr
  • Tik
  • eukaryotic translation initiation factor 2-alpha kinase 2
  • EIF2AK2
  • eif2ak2
  • Eif2ak2
抗原表位
AA 117-250
61
54
26
19
18
15
15
13
12
6
5
4
4
4
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用

291
83
43
2
2
2
2
1
1
1
1
宿主
小鼠
249
46
克隆类型
单克隆
标记
This EIF2AK2 antibody is un-conjugated
7
7
6
5
5
4
4
4
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
189
127
99
81
49
45
19
15
4
3
2
1
1
Supplier
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产品编号 ABIN968165
产品在该地区无法提供。
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN210946 IP WB Rabbit IgG AA 1-90 Log in to see Polyclonal
1 ABIN220857 ICC IF IP ELISA WB Rabbit IgG pThr451 Log in to see Polyclonal
1 ABIN4903556 IHC IP WB Rabbit IgG Log in to see

引用最多的anti-EIF2AK2 抗体 for Immunoprecipitation

Similar anti-EIF2AK2 抗体

应用范围 / 适用
Cytometry by Time of Flight (CyTOF) 1 抗体
ELISA 95 抗体
Enzyme Immunoassay (EIA) 4 抗体
Flow Cytometry (FACS) 19 抗体
Immunochromatography (IC) 1 抗体
Immunocytochemistry (ICC) 15 抗体
Immunofluorescence (IF) 46 抗体
Immunofluorescence (fixed cells) (IF/ICC) 2 抗体
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 49 抗体
Immunohistochemistry (IHC) 128 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 81 抗体
Immunoprecipitation (IP) 4 抗体
Western Blotting (WB) 187 抗体

General

抗原 Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) 抗体
抗原表位 AA 117-250
(61), (54), (26), (19), (18), (15), (15), (13), (12), (6), (5), (4), (4), (4), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用
(291), (83), (43), (2), (2), (2), (2), (1), (1), (1), (1)
宿主 小鼠
(249), (46)
克隆类型 (克隆位点)
单克隆   ( )
标记 This EIF2AK2 antibody is un-conjugated
(7), (7), (6), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(189), (127), (99), (81), (49), (45), (19), (15), (4), (3), (2), (1), (1)
Pubmed 4个引用可参考
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EIF2AK2抗体详情

EIF2AK2目标详情 使用细节 贮存及处理 ProductDetails: References for anti-EIF2AK2 antibody (ABIN968165) 图像
产品特性 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
纯化方法 The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
免疫原 Human p68 Kinase aa. 117-250
克隆位点 13-PKR
亚型 IgG1

EIF2AK2目标详情

EIF2AK2抗体详情 使用细节 贮存及处理 ProductDetails: References for anti-EIF2AK2 antibody (ABIN968165) 图像 回页首
抗原
别名 PKR (EIF2AK2 Antibody 摘要)
背景 Double stranded RNA (dsRNA) generated by most viruses during the infectious cycle is a potent stimulator of interferons. Interferons bind to cell surface receptors and stimulate the synthesis of several proteins that interfere with viral replication. One protein, 2'5'-oligo-adenylate synthetase, indirectly activates an endoribonuclease that degrades viral RNA. Another protein, p68 serine/threonine protein kinase (also known as PKR and TIK), is induced following interferon stimulation and activated by autophosphorylation in the presence of dsRNA. Upon activation, p68 phosphorylates the alpha subunit of the eukaryotic initiation factor 2 (eIF-2) resulting in inhibition of protein synthesis and, in turn, inhibition of viral replication. Evidence also suggests that p68 protein kinase inhibits proliferation and potentiates tumor suppressor function. In addition, p68 has been shown to phosphorylate Ikappa-B, thus activating NF-kappaB which induces interferon-beta gene transcription. This antibody is routinely tested by western blot analysis.
Synonyms: Protein Kinase R, p68 Kinase, TIK
分子量 68 kDa
研究领域 Signaling
途径 ER-Nucleus Signaling, Hepatitis C

使用细节

EIF2AK2抗体详情 EIF2AK2目标详情 贮存及处理 ProductDetails: References for anti-EIF2AK2 antibody (ABIN968165) 图像 回页首
说明

Related Products: ABIN968533, ABIN967389

限制 仅限研究用

贮存及处理

EIF2AK2抗体详情 EIF2AK2目标详情 使用细节 ProductDetails: References for anti-EIF2AK2 antibody (ABIN968165) 图像 回页首
状态 Liquid
浓度 250 μg/mL
缓冲液 Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store undiluted at -20° C.

ProductDetails: References for anti-EIF2AK2 antibody (ABIN968165)

EIF2AK2抗体详情 EIF2AK2目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Feng, Chong, Kumar, Williams: "Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 12, pp. 5447-51, 1992

Lee, Tomita, Hovanessian, Katze: "Characterization and regulation of the 58,000-dalton cellular inhibitor of the interferon-induced, dsRNA-activated protein kinase." in: The Journal of biological chemistry, Vol. 267, Issue 20, pp. 14238-43, 1992

Barber, Tomita, Hovanessian, Meurs, Katze: "Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli." in: Biochemistry, Vol. 30, Issue 42, pp. 10356-61, 1991

Meurs, Chong, Galabru, Thomas, Kerr, Williams, Hovanessian: "Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon." in: Cell, Vol. 62, Issue 2, pp. 379-90, 1990

图像

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厂商提供的图像
Western Blotting (WB) image for anti-EIF2AK2 抗体 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2) (AA 117-250) (ABIN968165) Western blot analysis of PKR on a A431 cell lysate (Human epithelial carcinoma, ATCC ...
Immunofluorescence (IF) image for anti-EIF2AK2 抗体 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2) (AA 117-250) (ABIN968165) Immunofluorescence staining of human endothelial cells.
 image for anti-EIF2AK2 抗体 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2) (AA 117-250) (ABIN968165) anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 117-250) antibody (Image 3)
Western Blotting (WB) image for anti-EIF2AK2 抗体 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2) (AA 117-250) (ABIN968165) anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 117-250) antibody (Image 4)