anti-CCR5 (CCR5) 抗体产品概述

Full name:
anti-C-C Chemokine Receptor Type 5 抗体 (CCR5)
在www.antibodies-online.cn可供510 C-C Chemokine Receptor Type 5 (CCR5) 抗体的35不同的供货商。 再加上,我们可以发CCR5 试剂盒 (38)CCR5 蛋白 (12)和数多这个蛋白质的别的产品。 总共571 CCR5产品已列进来了。
别名:
AM4-7, CC-CKR-5, CCCKR5, CCR-5, CCR1-L, CCR5, CCR5-L, CD195, CKR-5, Ckr5, Cmkbr5, GPCR, IDDM22

所有可销售的anti-CCR5 抗体

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引用最多的anti-CCR5 抗体

  1. Human Monoclonal CCR5 Primary Antibody for FACS, ICC - ABIN4899075 : Alonzo, Kozhaya, Rawlings, Reyes-Robles, DuMont, Myszka, Landau, Unutmaz, Torres: CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. in Nature 2013 (PubMed)
    Show all 17 references for 4899075

  2. Human Monoclonal CCR5 Primary Antibody for FACS - ABIN4895435 : Hartl, Krauss-Etschmann, Koller, Hordijk, Kuijpers, Hoffmann, Hector, Eber, Marcos, Bittmann, Eickelberg, Griese, Roos: Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 6 references for 4895435

  3. Human Monoclonal CCR5 Primary Antibody for FACS - ABIN1449163 : Nimura, Zhang, Okuma, Tanaka, Sunakawa, Yamamoto, Tanaka: Cross-linking cell surface chemokine receptors leads to isolation, activation, and differentiation of monocytes into potent dendritic cells. in Experimental biology and medicine (Maywood, N.J.) 2006 (PubMed)
    Show all 5 references for 1449163

  4. Human Monoclonal CCR5 Primary Antibody for FACS - ABIN2853594 : Ichiyama, Yokoyama-Kumakura, Tanaka, Tanaka, Hirose, Bannai, Edamatsu, Yanaka, Niitani, Miyano-Kurosaki, Takaku, Koyanagi, Yamamoto: A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 5 references for 2853594

  5. Human Monoclonal CCR5 Primary Antibody for FACS - ABIN4895433 : Maeda, Das, Yin, Tsuchiya, Ogata-Aoki, Nakata, Norman, Hackney, Takaoka, Mitsuya: Involvement of the second extracellular loop and transmembrane residues of CCR5 in inhibitor binding and HIV-1 fusion: insights into the mechanism of allosteric inhibition. in Journal of molecular biology 2008 (PubMed)
    Show all 4 references for 4895433

  6. Human Polyclonal CCR5 Primary Antibody for EIA, IF - ABIN372756 : Tan, Goedegebuure, Belt, Flaherty, Sankpal, Gillanders, Eberlein, Hsieh, Linehan: Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Show all 2 references for 372756

  7. Human Polyclonal CCR5 Primary Antibody for IF (p), IHC (p) - ABIN741375 : Ochoa-Callejero, Pérez-Martínez, Rubio-Mediavilla, Oteo, Martínez, Blanco: Maraviroc, a CCR5 antagonist, prevents development of hepatocellular carcinoma in a mouse model. in PLoS ONE 2013 (PubMed)

  8. Cow (Bovine) Polyclonal CCR5 Primary Antibody for WB - ABIN2779385 : Catano, Agan, Kulkarni, Telles, Marconi, Dolan, Ahuja: Independent effects of genetic variations in mannose-binding lectin influence the course of HIV disease: the advantage of heterozygosity for coding mutations. in The Journal of infectious diseases 2008 (PubMed)

  9. Human Polyclonal CCR5 Primary Antibody for IHC, ELISA - ABIN1532235 : Samson, Labbe, Mollereau, Vassart, Parmentier: Molecular cloning and functional expression of a new human CC-chemokine receptor gene. in Biochemistry 1996 (PubMed)

  10. Human Monoclonal CCR5 Primary Antibody for FACS - ABIN119679 : Mueller, Kelly, Strange: Pathways for internalization and recycling of the chemokine receptor CCR5. in Blood 2002 (PubMed)

更多抗CCR5的相互作用对抗体

Mouse (Murine) C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. this review discusses the role of CCR5 in recruitment and activation of myeloid-derived suppressor cells in melanoma

  2. These results suggested that CCR5 signaling is involved in embryo loss in Toxoplasma gondii infection during early pregnancy and that apoptosis is associated with embryo loss rather than direct damage to the fetoplacental tissues.

  3. The upregulation of CCR5 on the surface of the CD8 (显示 CD8A 抗体)(+) T cells increases the number of contacts with Ag-bearing dendritic cells, which ultimately results in increased CD8 (显示 CD8A 抗体)(+) T cell response to Ag rechallenge.

  4. CCL4 (显示 CCL4 抗体)-CCR5 axis can contribute to breast cancer metastasis to bone by mediating the interaction between cancer cells and fibroblasts in bone cavity.

  5. Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling.

  6. this study shows that diosgenin-mediated anti-allergic effects are associated with increased number of Foxp3 (显示 FOXP3 抗体)+ Treg cells expressing CCR5

  7. CCR5 deficiency increased the production of TNF-alpha (显示 TNF 抗体) following LPS (显示 TLR4 抗体) treatment through increased activation of the p38 (显示 CRK 抗体) pathway in the kidney, resulting in renal apoptosis and leukocyte infiltration and led to exacerbation of LPS (显示 TLR4 抗体)-induced acute kidney injury.

  8. In West Nile virus infection of the central nervous system, CCR5 activity is required to limit viral burden in the cerebral cortex.

  9. CCR5 blockade suppresses B16 melanoma growth by inhibiting of IL-6 (显示 IL6 抗体)-Stat3 (显示 STAT3 抗体) signaling pathway via upregulation of SOCS3 (显示 SOCS3 抗体).

  10. Data show that the activation of mammalian target of rapamycin (显示 FRAP1 抗体) complex mTORC1 during encephalomyocarditis virus infection is chemokine (C-C) receptor 5-dependent and promotes the translation of inducible NO synthase (iNOS (显示 NOS2 抗体)) and cyclooxygenase (COX)-2 (显示 COX2 抗体).

Cow (Bovine) C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CCR5 expression.

Rhesus Monkey C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. CCR5 inhibition may provide a cardioprotective benefit in SIV infection by preventing cardiomyocyte CCR5 signaling.

  2. A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251.

  3. CCR5 downregulation on CD4(+) T cells by TCR activation has no measurable effect on susceptibility to SAIDS.

  4. CD4 and CD8 T cells are more vulnerable to SIV infection, indicating the the ability to express CCR5 may activate and hassten T cell death by SIV infection in vitro.

  5. Results estimate the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut (显示 GUSB 抗体).

  6. observed a significantly higher loss of CCR5(+) CD45RA(-) CD4 (显示 CD4 抗体)(+) T cells in CD8 (显示 CD8A 抗体)(+) lymphocyte-depleted macaques than in controls

  7. Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 and CXCR4 (显示 CXCR4 抗体) for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 (显示 CXCR4 抗体) almost exclusively

Human C-C Chemokine Receptor Type 5 (CCR5) interaction partners

  1. this review discusses the role of CCR5 in recruitment and activation of myeloid-derived suppressor cells in melanoma

  2. CCR5 is highly expressed in active inflammatory bowel disease, and it has positive correlation with lymphocyte grade and negative correlation with expression of beta-arrestin2 (显示 ARRB2 抗体).

  3. this study shows that the dominant signature of resistance to HIV infection in this cohort of exposed but uninfected individuals was lower T-cell CCR5 expression

  4. the level of IFNAR1 (显示 IFNAR1 抗体), IFNAR2 (显示 IFNAR2 抗体), and CCR5 mRNA expression was found to be significantly lower in the responders than nonresponders.Our results highlighted the significance of IFNAR (显示 IFNAR1 抗体) and CCR5 genes in multiple sclerosis risk and the response to IFN-b therapy.

  5. Env (显示 ERVW-1 抗体) regions that respond to CCR5 binding was located in the gp120 (显示 ITIH4 抗体) alpha1 helix and in the gp41 HR1 heptad repeat and membrane-proximal external region.

  6. A frameshift mutation in CCR5 was associated, but not significantly, with sporadic inclusion body myositis.

  7. study revealed that while HIV-1 gp120 (显示 ITIH4 抗体) and Staph aureus LukED both target CCR5, they bind to different regions of the receptor, highlighting the divergence of the pathogens

  8. Genetic variation of CCR5 gene demonstrates a possible association with hypertension, diabetes mellitus and atherosclerosis comorbidity in patient treated with hemodialysis.

  9. Findings indicate the importance of chemokine (CC motif) ligand 5 (CCL5 (显示 CCL5 抗体)) genetic variability and CCL5 (显示 CCL5 抗体)-CCR5 (CC chemokine receptor 5) axis on the susceptibility to HCV.

  10. The transferred nuclear Overhauser effect (TRNOE) crosspeaks in the ternary complex were assigned to the specific Tyr (显示 TYR 抗体) protons in the human C-C chemokine receptor 5 (CCR5) chemokine receptor (显示 CCR1 抗体) peptide and to methyl protons, predominantly of isoleucine residues, and also of leucine and/or valine residues of HIV-1 gp120 (显示 ITIH4 抗体) envelope protein.

CCR5 抗原简介

Antigen Summary

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with CCR5

  • chemokine (C-C motif) receptor 5 (gene/pseudogene) (CCR5) 抗体
  • chemokine (C-C motif) receptor 5 (Ccr5) 抗体
  • chemokine (C-C motif) receptor 5 (CCR5) 抗体
  • chemokine (C-C motif) receptor 2 (CCR2) 抗体
  • C-C chemokine receptor type 5-like (LOC100399144) 抗体
  • AM4-7 抗体
  • CC-CKR-5 抗体
  • CCCKR5 抗体
  • CCR-5 抗体
  • CCR1-L 抗体
  • CCR5 抗体
  • CCR5-L 抗体
  • CD195 抗体
  • CKR-5 抗体
  • Ckr5 抗体
  • Cmkbr5 抗体
  • GPCR 抗体
  • IDDM22 抗体

Protein level used designations for CCR5

C-C chemokine receptor type 5 , C-C motif chemokine receptor 5 A159A , HIV-1 fusion coreceptor , chemokine receptor CCR5 , chemr13 , C-C CKR-5 , CC-CKR-5 , CCR-5 , MIP-1 alpha receptor , chemokine (C-C) receptor 5 , chemokine C-C motif receptor 5 , C-C chemokine receptor 11 like , CC chemokine receptor 5 , chemokine receptor 5 , CC chemokine receptor type 5 , C-C chemokine receptor 5 , chemokine (C-C motif) receptor 5 , C-C chemokine receptor 5 like , C-C chemokine receptor type 2 , C-C chemokine receptor type 5-like

GENE ID SPECIES
1234 Homo sapiens
117029 Rattus norvegicus
414371 Sus scrofa
420695 Gallus gallus
450128 Pan troglodytes
484789 Canis lupus familiaris
493769 Felis catus
497017 Bos taurus
735311 Macaca mulatta
100048935 Equus caballus
100101579 Oryctolagus cuniculus
100126710 Papio anubis
100190809 Pongo abelii
12774 Mus musculus
420696 Gallus gallus
100399144 Callithrix jacchus
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