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CCR5 抗体 (Middle Region)

The 兔 多克隆 anti-CCR5 antibody (ABIN2779385) specifically detects CCR5 in WB. The antibody is reactive with 人, Cow 和 Pig samples.
产品编号 ABIN2779385
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCR5 抗体 (Middle Region) (ABIN2779385)

抗原

See all CCR5 抗体
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

  • 227
  • 80
  • 61
  • 12
  • 2
  • 2
  • 2
  • 1
  • 1
人, Cow, Pig

宿主

  • 179
  • 46
  • 12
  • 11
  • 1
  • 1
兔

克隆类型

  • 176
  • 65
  • 5
多克隆

标记

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This CCR5 antibody is un-conjugated

应用范围

  • 162
  • 86
  • 84
  • 37
  • 28
  • 19
  • 14
  • 14
  • 11
  • 10
  • 9
  • 4
  • 2
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  • 1
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Western Blotting (WB)
  • 抗原表位

    • 35
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    • 12
    • 9
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    • 6
    • 5
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    • 2
    • 1
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    Middle Region

    原理

    CCR5 Antibody - middle region

    序列

    SHFPYSQYQF WKNFQTLKIV ILGLVLPLLV MVICYSGILK TLLRCRNEKK

    预测反应

    Cow: 92%, Human: 100%, Pig: 100%

    产品特性

    This is a rabbit polyclonal antibody against CCR5. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CCR5
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30788-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CCR5

    背景

    Background Information: CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this protein was also detected in a promyeloblastic cell line, suggesting that CCR5 may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.

    Gene Name: Chemokine (C-C motif) receptor 5 (gene/pseudogene)

    Alternative Symbols: CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5

    Protein Name: C-C chemokine receptor type 5

    分子量

    41kDa

    基因ID

    1234

    NCBI登录号

    NP_000570

    UniProt

    P51681

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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