STAT2 抗体 (AA 1-178)
(5 references)-
- 抗原 See all STAT2 抗体
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
-
抗原表位
- AA 1-178
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This STAT2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Stat2 aa. 1-178
- 克隆位点
- 22-Stat2
- 亚型
- IgG2a
- Top Product
- Discover our top product STAT2 Primary Antibody
-
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 151-250) antibody
STAT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 616-849) antibodySTAT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 587-838) antibodySTAT2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (Tyr1221), (Tyr1222) antibodySTAT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (AA 742-851) antibodySTAT2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5G7 unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (C-Term) antibodySTAT2 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (pTyr690) antibodySTAT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) antibodySTAT2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal STAT2-2650 unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) antibodySTAT2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Signal Transducer and Activator of Transcription 2, 113kDa (STAT2) (Internal Region), (pTyr690) antibodySTAT2 适用: 人, 大鼠, 小鼠, 马, Macaque, Pig, Vervet Monkey, Cow, 犬, Chimpanzee WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 说明
-
Related Products: ABIN968586, ABIN967389
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
-
-
: "Regulation of STAT protein synthesis by c-Cbl." in: Oncogene, Vol. 20, Issue 50, pp. 7326-33, (2001) (PubMed).
: "Role of the intracellular domain of the human type I interferon receptor 2 chain (IFNAR2c) in interferon signaling. Expression of IFNAR2c truncation mutants in U5A cells." in: The Journal of biological chemistry, Vol. 275, Issue 31, pp. 23981-5, (2000) (PubMed).
: "Pervanadate mimics IFNgamma-mediated induction of ICAM-1 expression via activation of STAT proteins." in: The Journal of investigative dermatology, Vol. 108, Issue 3, pp. 295-301, (1997) (PubMed).
: "Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei." in: Science (New York, N.Y.), Vol. 261, Issue 5129, pp. 1733-6, (1993) (PubMed).
: "The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 16, pp. 7840-3, (1992) (PubMed).
-
: "Regulation of STAT protein synthesis by c-Cbl." in: Oncogene, Vol. 20, Issue 50, pp. 7326-33, (2001) (PubMed).
-
- 抗原
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- 别名
- Stat2 (STAT2 产品)
- 别名
- wu:fj84d07 antibody, p113 antibody, stat2 antibody, 1600010G07Rik antibody, AW496480 antibody, ISGF-3 antibody, P113 antibody, STAT113 antibody, signal transducer and activator of transcription 2 antibody, AGAP000099-PA antibody, stat2 antibody, STAT2 antibody, Stat2 antibody
- 背景
- The Stat proteins function as both cytoplasmic signal transducers and activators of transcription. Stat91/84 (the two proteins are the result of alternate splicing-Stat91 has an additional 38 C-terminal amino acids) and Stat113 were the first identified members of this protein family. These three polypeptides contain both SH2 and SH3 domains and have also been described as members of the ISGF3 (interferon-stimulated gene factor 3) complex. With the discovery of additional members of the Stat family (Stats3 & 4), the nomenclature has been revised to indicate the Stat family members in the order of their discovery. Stat 91, 84, and 113 have become Stat1alpha, Stat1beta, and Stat2, respectively. In response to IFN-alpha treatment, Stat1alpha, Stat1beta, and Stat2 become tyrosine-phosphorylated and migrate to the nucleus where they join a 48 kDa DNA binding protein and subsequently direct the transcription at IFN-alpha responsive elements. The genes encoding Stat2 and Stat1 are closely related. An extended acidic C-terminal region exclusive to Stat2 implicates a potential role in gene activation. Stat2 phosphorylation can occur independently of Stat1alpha, but phosphorylated Stat2 does appear to be dependent on its interaction with Stat1alpha for efficient nuclear localization and/or stability.
- 分子量
- 113 kDa
- 途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
-
