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TYROBP 抗体 (C-Term)

TYROBP 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN955408
发货至: 中国
  • 抗原 See all TYROBP 抗体
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    抗原表位
    • 16
    • 15
    • 15
    • 10
    • 1
    • 1
    • 1
    AA 84-113, C-Term
    适用
    • 48
    • 20
    • 4
    宿主
    • 65
    • 1
    • 1
    克隆类型
    • 58
    • 9
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TYROBP antibody is un-conjugated
    应用范围
    • 40
    • 29
    • 26
    • 26
    • 21
    • 18
    • 11
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects TYROBP / DAP12 (C-term).
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein A column followed by peptide affinity purification
    免疫原
    KLH conjugated synthetic peptide between 84~113 amino acids from the C-terminal region of human TYROBP
    亚型
    Ig Fraction
    Top Product
    Discover our top product TYROBP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    TYROBP / DAP12 (TYROBP 产品)
    背景
    TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL.Synonyms: DNAX-activation protein 12, KARAP, Killer-activating receptor-associated protein, TYRO protein tyrosine kinase-binding protein
    基因ID
    7305
    NCBI登录号
    NP_003323
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