ADAMTS4 抗体 (C-Term)
(2 references)-
- 抗原 See all ADAMTS4 抗体
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
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抗原表位
- AA 813-837, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAMTS4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) detection. Tested with WB, IHC-P, ELISA in Human.
- 序列
- TPQDWLHRRA QILEILRRRP WAGRK
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif, 4
Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 4 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS4 (813-837aa TPQDWLHRRAQILEILRRRPWAGRK), different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ADAMTS4 Primary Antibody
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anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) antibody
ADAMTS4 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (AA 213-319) antibodyADAMTS4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (Internal Region) antibodyADAMTS4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (AA 705-736), (C-Term) antibodyADAMTS4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB18037 unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (N-Term) antibodyADAMTS4 适用: 人, 小鼠, 大鼠, 马, 犬, Cow, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (AA 501-839) antibodyADAMTS4 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (AA 437-575) antibodyADAMTS4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (Metalloprotease Domain) antibodyADAMTS4 适用: 人, 马, 犬, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (C-Term) antibodyADAMTS4 适用: 人, 马, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) (Disintegrin-like Domain) antibodyADAMTS4 适用: 人, 小鼠, 马, 犬, 猴, Cow, 豚鼠, Bat, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "Protective effect of calcitonin on lumbar fusion-induced adjacent-segment disc degeneration in ovariectomized rat." in: BMC musculoskeletal disorders, Vol. 16, pp. 342, (2016) (PubMed).
: "Electrospun poly(L-lactide)/poly(?-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71265, (2013) (PubMed).
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: "Protective effect of calcitonin on lumbar fusion-induced adjacent-segment disc degeneration in ovariectomized rat." in: BMC musculoskeletal disorders, Vol. 16, pp. 342, (2016) (PubMed).
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- 抗原
- ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
- 别名
- ADAMTS4 (ADAMTS4 产品)
- 别名
- 3830423K05 antibody, ADAM-TS4 antibody, ADAMTS-2 antibody, ADMP-1 antibody, mKIAA0688 antibody, ADAMTS-4 antibody, ADAMTS4 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antibody, Adamts4 antibody, ADAMTS4 antibody
- 背景
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ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4, is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
Synonyms: ADAM TS4 | ADAM-TS4 | ADAMTS4 protein | ADMP1 | ADMP-1 | Aggrecanase 1 | Aggrecanase1 | Aggrecanase-1 | ATS4 | KIAA 0688 | KIAA0688 | O75173 - 基因ID
- 9507
- UniProt
- O75173
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