JAK3 抗体 (Middle Region)
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- 抗原 See all JAK3 抗体
- JAK3 (Janus Kinase 3 (JAK3))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 马, Pig, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JAK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KLLPLDKDYY VVREPGQSPI FWYAPESLSD NIFSRQSDVW SFGVVLYELF
- 预测反应
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against JAK3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human JAK3
- Top Product
- Discover our top product JAK3 Primary Antibody
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anti-Janus Kinase 3 (JAK3) (AA 716-967) antibody
JAK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) antibodyJAK3 适用: 人, 小鼠 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5H2 unconjugated
anti-Janus Kinase 3 (JAK3) (AA 601-700) antibodyJAK3 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) antibodyJAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) (Tyr785) antibodyJAK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) (AA 750-850) antibodyJAK3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) (AA 751-800) antibodyJAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) antibodyJAK3 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 1C7 unconjugated Recombinant Antibody
anti-Janus Kinase 3 (JAK3) (pTyr785) antibodyJAK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 3 (JAK3) (pTyr980), (pTyr981) antibodyJAK3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1124 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- JAK3 (Janus Kinase 3 (JAK3))
- 别名
- JAK3 (JAK3 产品)
- 别名
- JAK-3 antibody, JAK3_HUMAN antibody, JAKL antibody, L-JAK antibody, LJAK antibody, fae antibody, wil antibody, RATJAK3 antibody, JAK antibody, Janus kinase 3 antibody, JAK3 antibody, Jak3 antibody
- 背景
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JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases, which is involved in cytokine receptor-mediated intracellular signal transduction. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in JAK3 are associated with autosomal SCID (severe combined immunodeficiency disease).The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Protein Interaction Partner: Socs5, KIT, IL7R, TYK2, STAT6, STAT3, JAK2, JAK1, IL4R, GTF2B, ERBB3, CDK1, CD81, APOA1, UBC, SOCS3, UHRF2, STAT5A, IKBKG, ALK, SH2B2, TIAF1, INPP5D, PTPN2, STAM2, PRMT5, SOCS1, KHDRBS1, STAM, PTK2B, IRS2, SHB, JAK3, IL2RG, VIL1, FES, CD247, PTPN6, PIK3R1
Protein Size: 1124 - 分子量
- 125 kDa
- 基因ID
- 3718
- NCBI登录号
- NM_000215, NP_000206
- UniProt
- P52333
- 途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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