JAK3 抗体 (AA 751-800)
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北京 101111
Quick Overview for JAK3 抗体 (AA 751-800) (ABIN1532701)
抗原
See all JAK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 751-800
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原理
- JAK3 Antibody
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特异性
- JAK3 Polyclonal Antibody detects endogenous levels of JAK3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human JAK3. AA range:751-800
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- JAK3 (Janus Kinase 3 (JAK3))
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别名
- JAK3
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背景
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Synonyms: JAK3, Tyrosine-protein kinase JAK3, Janus kinase 3, JAK-3, Leukocyte janus kinase, L-JAK
Background: The protein encoded byThis gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],
Gene Name: JAK3
Protein Name: Tyrosine-protein kinase JAK3
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分子量
- 125 kDa
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基因ID
- 3718
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OMIM
- 600173
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UniProt
- P52333
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
抗原
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