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MAP3K7 抗体 (pThr187, Thr187)

MAP3K7 适用: 人 EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358291
发货至: 中国
  • 抗原 See all MAP3K7 抗体
    MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
    抗原表位
    • 17
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr187, Thr187
    适用
    • 102
    • 40
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 96
    • 6
    • 1
    克隆类型
    • 94
    • 9
    多克隆
    标记
    • 67
    • 7
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP3K7 antibody is un-conjugated
    应用范围
    • 80
    • 60
    • 41
    • 16
    • 10
    • 8
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    特异性
    This antibody detects MAP3K7 pThr187. Predicted to cross react with Mouse (100 % Antigen Homology).
    纯化方法
    Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Thr187 of human MAP3K7.
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAP3K7 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Dot Blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
    别名
    TAK1 / MAP3K7 (MAP3K7 产品)
    别名
    si:ch211-225h9.1 antibody, zgc:110612 antibody, Tak1 antibody, MEKK7 antibody, TAK1 antibody, TGF1a antibody, B430101B05 antibody, C87327 antibody, mitogen-activated protein kinase kinase kinase 7 antibody, mitogen activated protein kinase kinase kinase 7 antibody, map3k7 antibody, Map3k7 antibody, MAP3K7 antibody
    背景
    MAP3K7 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.Synonyms: Mitogen-activated protein kinase kinase kinase 7, TAK-1, TAK1, TGF-beta-activated kinase 1, Transforming growth factor-beta-activated kinase 1
    分子量
    64099 Da
    基因ID
    6885, 9606
    UniProt
    O43318
    途径
    NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
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