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TIA1 抗体 (C-Term)

TIA1 适用: 人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN310093
发货至: 中国
  • 抗原 See all TIA1 抗体
    TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
    抗原表位
    • 15
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 71
    • 36
    • 33
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 兔, Cow, 豚鼠, 马
    宿主
    • 55
    • 15
    • 1
    克隆类型
    • 48
    • 23
    多克隆
    标记
    • 33
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIA1 antibody is un-conjugated
    应用范围
    • 41
    • 21
    • 16
    • 16
    • 14
    • 13
    • 11
    • 9
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    QAWNQQGFNQ TQSSAPWMGP NYGVQPPQGQ NGSMLPNQPS GYRVAGYETQ
    预测反应
    Cow: 82%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against TIA1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human TIA1
    Top Product
    Discover our top product TIA1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 375 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
    别名
    TIA1 (TIA1 产品)
    别名
    tia1 antibody, 2310050N03Rik antibody, AI256674 antibody, TIA-1 antibody, mTIA-1 antibody, WDM antibody, TIAL1 antibody, TIAR antibody, tia-1 antibody, nucleolysin TIA-1 isoform p40 antibody, hypothetical protein antibody, nucleolysin TIAR antibody, nucleolysin tia-1 antibody, nucleolysin TIA-1 antibody, cytotoxic granule-associated RNA binding protein 1 antibody, TIA1 cytotoxic granule associated RNA binding protein antibody, TIA1 cytotoxic granule-associated RNA binding protein antibody, TIA1 cytotoxic granule-associated RNA binding protein L homeolog antibody, PTRG_10065 antibody, PGTG_08590 antibody, LOC5568274 antibody, CpipJ_CPIJ013665 antibody, VDBG_07004 antibody, MGYG_03339 antibody, Tsp_15456 antibody, tia1 antibody, Tia1 antibody, TIA1 antibody, tia1.L antibody
    背景
    TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing.The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
    Alias Symbols: TIA-1
    Protein Interaction Partner: NEDD8, BMI1, SOX2, VCAM1, ITGA4, FN1, FMNL1, WDR6, SRSF3, CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL5, Rc3h1, UBC, RICTOR, FASTK,
    Protein Size: 375
    分子量
    42 kDa
    基因ID
    7072
    NCBI登录号
    NM_022037, NP_071320
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