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IRF3 抗体 (C-Term)

IRF3 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2779404
发货至: 中国
  • 抗原 See all IRF3 抗体
    IRF3 (Interferon Regulatory Factor 3 (IRF3))
    抗原表位
    • 18
    • 16
    • 15
    • 14
    • 13
    • 9
    • 8
    • 7
    • 5
    • 5
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    C-Term
    适用
    • 144
    • 91
    • 56
    • 31
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 兔, 绵羊, 豚鼠, 马
    宿主
    • 154
    • 13
    • 2
    克隆类型
    • 136
    • 33
    多克隆
    标记
    • 90
    • 12
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    This IRF3 antibody is un-conjugated
    应用范围
    • 123
    • 69
    • 33
    • 32
    • 29
    • 27
    • 20
    • 12
    • 10
    • 8
    • 6
    • 4
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    Western Blotting (WB)
    序列
    SWPQDQPWTK RLVMVKVVPT CLRALVEMAR VGGASSLENT VDLHISNSHP
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Sheep: 100%
    产品特性
    This is a rabbit polyclonal antibody against IRF3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human IRF3
    Top Product
    Discover our top product IRF3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 427 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    IRF3 (Interferon Regulatory Factor 3 (IRF3))
    别名
    IRF3 (IRF3 产品)
    别名
    irf3 antibody, IRF3 antibody, C920001K05Rik antibody, IRF-3 antibody, interferon regulatory factor 3 antibody, interferon regulatory factor 7 antibody, irf3 antibody, IRF3 antibody, irf-3 antibody, Irf3 antibody, IRF7 antibody
    背景
    IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
    Protein Interaction Partner: IRF3, UBC, TMEM173, POLR2A, DEAF1, CREBBP, MAFB, vIRF-3, SMAD4, SMAD2, FOXO1, vIRF-1, EP300, SGTA, PEX19, HSP90AA1, PIAS4, TBK1, TOMM70A, TLR2, MAPK9, MAPK8, MAVS, DDX58, TRAF3, ISG15, TRIM21, PIN1, IRF7, HERC5, IKBKE, CUL1, SUMO2, XIAP, HDAC3, SOCS1, RBL
    Protein Size: 427
    分子量
    47 kDa
    基因ID
    3661
    NCBI登录号
    NM_001571, NP_001562
    UniProt
    Q14653
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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