TNFRSF13C 抗体 (FITC)
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- 抗原 See all TNFRSF13C 抗体
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF13C antibody is conjugated to FITC
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Functional Studies (Func), Intracellular Flow Cytometry (ICFC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
- 克隆位点
- 11C1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNFRSF13C Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
- 别名
- CD268 (TNFRSF13C 产品)
- 别名
- RGD1560810 antibody, TNFRSF13C antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, TNF receptor superfamily member 13C antibody, uncharacterized LOC746611 antibody, tumor necrosis factor receptor superfamily, member 13c antibody, TNFRSF13C antibody, Tnfrsf13c antibody, LOC746611 antibody
- 背景
- B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κB activation.
- 途径
- NF-kappaB Signaling
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