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TYROBP 抗体

TYROBP 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265057
发货至: 中国
  • 抗原 See all TYROBP 抗体
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    适用
    • 48
    • 19
    • 4
    人, 小鼠
    宿主
    • 65
    • 1
    • 1
    克隆类型
    • 58
    • 9
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TYROBP antibody is un-conjugated
    应用范围
    • 40
    • 30
    • 26
    • 26
    • 21
    • 18
    • 12
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    This antibody is specific to DAP12.
    纯化方法
    Purified
    免疫原
    Recombinant DAP12 protein.
    Top Product
    Discover our top product TYROBP Primary Antibody
  • 应用备注
    Western Blot. Immunoprecipitation: Use 2-4 μg/mL of protein lysate. Positive Control: NKp44 positive cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS, 0.08 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    TYROBP / DAP12 (TYROBP 产品)
    别名
    TYROBP antibody, DAP12 antibody, tyrpbp antibody, Karap antibody, KARAP antibody, PLOSL antibody, Ly83 antibody, dap12 antibody, TYRO protein tyrosine kinase binding protein antibody, Tyro protein tyrosine kinase binding protein antibody, TYROBP antibody, tyrobp antibody, Tyrobp antibody
    背景
    DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells (1,2). DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction (3). Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice (4,5), as well as presenile dementia and bone cysts in humans (6).Synonyms: DNAX-activation protein 12, KARAP, Killer-activating receptor-associated protein, TYRO protein tyrosine kinase-binding protein
    基因ID
    7305
    NCBI登录号
    NP_003323
    UniProt
    O43914
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