PTK2B 抗体 (pTyr402)
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- 抗原 See all PTK2B 抗体
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
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抗原表位
- pTyr402
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTK2B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- This antibody detects endogenous levels of Pyk2 only when phosphorylated at Tyrosine 402.
- 纯化方法
- Immunoaffinity Chromatography using epitope-specific phosphopeptide.
- 免疫原
- The antiserum was produced against synthesized phosphopeptide derived from human Pyk2 around the phosphorylation site of tyrosine 402 (D-I-YP-A-E).
- Top Product
- Discover our top product PTK2B Primary Antibody
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anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody
PTK2B 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 1-1009) antibodyPTK2B 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibodyPTK2B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1F9 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibodyPTK2B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 805-838), (C-Term) antibodyPTK2B 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB50594 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) antibodyPTK2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibodyPTK2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal X1 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 812-861) antibodyPTK2B 适用: 人, 小鼠, 大鼠, 犬, 兔, Pig, 马, 猴, 豚鼠, Cow, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 815-997) antibodyPTK2B 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 5E2D5 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (Tyr579) antibodyPTK2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- 别名
- FAK2 / PTK2B (PTK2B 产品)
- 别名
- CADTK antibody, CAKB antibody, FADK2 antibody, FAK2 antibody, PKB antibody, PTK antibody, PYK2 antibody, RAFTK antibody, CAKbeta antibody, E430023O05Rik antibody, Raftk antibody, Pyk2 antibody, fak1b antibody, ptk2.2 antibody, ptk2b antibody, si:ch1073-355e8.1 antibody, protein tyrosine kinase 2 beta antibody, PTK2 protein tyrosine kinase 2 beta antibody, protein tyrosine kinase 2aa antibody, PTK2B antibody, Ptk2b antibody, ptk2aa antibody
- 背景
- PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. PYK2 activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity.Synonyms: CADTK, CAK-beta, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, PYK2, Proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, RAFTK, Related adhesion focal tyrosine kinase
- 基因ID
- 2185
- NCBI登录号
- NP_004094
- UniProt
- Q14289
- 途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
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