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Integrin beta 2 抗体 (Biotin)

ITGB2 适用: 大鼠 FACS, IHC (fro) 宿主: 小鼠 Monoclonal WT-3 Biotin
产品编号 ABIN120418
发货至: 中国
  • 抗原 See all Integrin beta 2 (ITGB2) 抗体
    Integrin beta 2 (ITGB2)
    适用
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    大鼠
    宿主
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    小鼠
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    单克隆
    标记
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    This Integrin beta 2 antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This Antibody is specific for the β subunit of LFA-1. This antibody also recognizes MAC-1 and p150, 95 as well as LFA-1, since they all contain the same β subunit. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1
    克隆位点
    WT-3
    亚型
    IgG1
    Top Product
    Discover our top product ITGB2 Primary Antibody
  • 应用备注
    Immunoprecipitation. Flow cytometry. Immunohistochemistry on cryostat sections. Functional studies: in vivo/in vitro.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, pH 7.2, with 0.09 % NaN3 and 0.5 % BSA.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Integrin beta 2 (ITGB2)
    别名
    CD18 / ITGB2 (ITGB2 产品)
    背景
    LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of α and β subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
    基因ID
    25021
    NCBI登录号
    NP_036843
    UniProt
    Q9JI30
    途径
    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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